Why is this medication prescribed?

Bexagliflozin is a medication prescribed to treat type 2 diabetes. It belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. These drugs work by helping the kidneys remove glucose from the bloodstream through the urine, thereby lowering blood sugar levels. Bexagliflozin is typically used in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes. It can help lower A1C levels and reduce the risk of cardiovascular events in diabetic patients. However, like any medication, it’s important to use it as directed by a healthcare professional and to be aware of potential side effects and contraindications.

How should this medicine be used?

Bexagliflozin should be used exactly as prescribed by a healthcare professional. The typical starting dose for Bexagliflozin is 150 mg once daily, taken orally with or without food. However, the dosage may vary depending on individual factors such as kidney function and other medications being taken.

It’s important to follow the instructions provided by the prescribing doctor or pharmacist. Bexagliflozin is often taken in conjunction with other medications for diabetes management, such as metformin or insulin.

Patients should continue to follow a healthy diet and exercise regimen as recommended by their healthcare provider while taking Bexagliflozin.

If a dose of Bexagliflozin is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. Doubling up on doses should be avoided.

If there are any questions or concerns about how to use Bexagliflozin, it’s important to consult a healthcare professional for guidance.

Other uses for this medicine

Bexagliflozin is primarily used for the treatment of type 2 diabetes. While it is primarily indicated for this purpose, there might be some off-label uses that healthcare professionals may consider in certain situations. However, any off-label use should only be undertaken under the guidance and supervision of a qualified healthcare provider.

What special precautions should I follow?

As for special precautions when using Bexagliflozin, here are some important points to consider:

• Kidney function: Bexagliflozin works by increasing the excretion of glucose through the kidneys. Therefore, it’s important to monitor kidney function regularly, especially in patients with pre-existing kidney problems.
• Dehydration: Bexagliflozin can increase the risk of dehydration, particularly in elderly patients or those taking diuretic medications. Patients should be advised to drink plenty of fluids, especially water, and to report any signs of dehydration such as dizziness, weakness, or decreased urine output.
• Hypotension (low blood pressure): Bexagliflozin may cause a decrease in blood pressure, particularly during the initial period of treatment. Patients should be monitored for symptoms of hypotension, such as dizziness or lightheadedness, especially when standing up from a sitting or lying position.
• Genital mycotic infections: Bexagliflozin may increase the risk of genital mycotic (yeast) infections, particularly in women. Patients should be advised to practice good hygiene and report any symptoms of vaginal itching, discharge, or discomfort to their healthcare provider.
• Hypoglycemia: While Bexagliflozin itself does not typically cause hypoglycemia (low blood sugar), it may increase the risk when used in combination with other antidiabetic medications such as insulin or sulfonylureas. Patients should be educated about the signs and symptoms of hypoglycemia and how to treat it.
• Surgical procedures: Patients taking Bexagliflozin should inform their healthcare provider if they are undergoing surgery, as temporary discontinuation of the medication may be necessary, particularly if fasting is required.
• Pregnancy and breastfeeding: The safety of Bexagliflozin during pregnancy and breastfeeding has not been established. Healthcare providers should weigh the potential risks and benefits before prescribing Bexagliflozin to pregnant or breastfeeding women.

These are just some general precautions associated with Bexagliflozin use. It’s important for patients to discuss their medical history and any concerns with their healthcare provider before starting treatment with this medication.

What special dietary instructions should I follow?

• There are no specific dietary restrictions associated with Bexagliflozin use. However, it’s important to maintain a healthy diet as recommended by your healthcare provider for diabetes management.
• Be mindful of carbohydrate intake and aim for a balanced diet rich in fruits, vegetables, lean proteins, and whole grains.

What should I do if I forget a dose?

• If a dose of Bexagliflozin is missed, take it as soon as remembered, unless it’s almost time for the next scheduled dose.
• If it’s nearly time for the next dose, skip the missed one and resume the regular dosing schedule.
• Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Bexagliflozin, like any medication, can cause side effects in some people. Common side effects of Bexagliflozin may include:

• Genital yeast infections: Women may experience vaginal itching, discharge, or discomfort due to an increased risk of genital mycotic (yeast) infections.
• Urinary tract infections: Some individuals may develop urinary tract infections, which can cause symptoms such as pain or burning during urination, frequent urination, or urgency to urinate.
• Increased urination: Bexagliflozin works by increasing glucose excretion through the urine, which can lead to increased urination (polyuria).
• Hypotension (low blood pressure): Bexagliflozin may cause a decrease in blood pressure, particularly during the initial period of treatment, leading to symptoms such as dizziness or lightheadedness.
• Dehydration: Bexagliflozin can increase the risk of dehydration, especially in elderly patients or those taking diuretic medications, resulting in symptoms such as weakness, dizziness, or decreased urine output.
• Hypoglycemia (low blood sugar): While Bexagliflozin itself does not typically cause hypoglycemia, it may increase the risk when used in combination with other antidiabetic medications such as insulin or sulfonylureas.
• Increased cholesterol levels: Some individuals may experience an increase in cholesterol levels while taking Bexagliflozin.
• Ketoacidosis: In rare cases, Bexagliflozin may lead to a serious condition called diabetic ketoacidosis (DKA), characterized by high levels of ketones in the blood.
• Allergic reactions: Allergic reactions to Bexagliflozin are rare but possible and may include symptoms such as rash, itching, swelling, or difficulty breathing.

It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects not listed here. If you experience any unusual or severe side effects while taking Bexagliflozin, it’s essential to contact your healthcare provider promptly.

What should I know about storage and disposal of this medication?

Storage and disposal of Bexagliflozin:

• Storage:
  • Store Bexagliflozin tablets at room temperature away from moisture and heat.
  • Keep the medication in its original container with the lid tightly closed.
  • Avoid storing Bexagliflozin in the bathroom, as moisture and humidity can affect its stability.
• Disposal:
  • Dispose of unused or expired Bexagliflozin tablets properly according to local regulations or guidelines.
  • Do not flush Bexagliflozin down the toilet or pour it into a drain unless instructed to do so.
  • Consult with a pharmacist or healthcare provider for guidance on safe disposal methods.

In case of emergency/overdose

• In case of an emergency or suspected overdose of Bexagliflozin, contact your local poison control center (such as the National Poison Control Center at 1-800-222-1222 in the United States) or seek medical attention immediately.
• Symptoms of overdose may include hypotension (low blood pressure), dehydration, and electrolyte imbalances.

What other information should I know?

• Inform all healthcare providers involved in your care, including doctors, dentists, and pharmacists, that you are taking Bexagliflozin.
• Attend regular follow-up appointments with your healthcare provider to monitor your response to treatment and assess for any potential side effects or complications.
• Keep a list of all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and supplements, and share this information with your healthcare provider.
• Be aware of signs and symptoms of potential complications associated with Bexagliflozin, such as genital yeast infections, urinary tract infections, and dehydration, and promptly report any concerns to your healthcare provider.
• Follow your healthcare provider’s instructions regarding diet, exercise, blood sugar monitoring, and other aspects of diabetes management while taking Bexagliflozin.

By being informed about storage, disposal, emergency procedures, and other important information, you can safely and effectively use Bexagliflozin as part of your diabetes management plan. If you have any questions or concerns, don’t hesitate to discuss them with your healthcare provider.