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Beovu (Generic Brolucizumab-dbll Injection)

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Why is this medication prescribed?

Beovu (brolucizumab) is a prescription medication used to treat wet age-related macular degeneration (AMD). Wet AMD is a progressive eye disease that can cause vision loss over time. Beovu works by inhibiting vascular endothelial growth factor (VEGF), a protein that contributes to the growth of abnormal blood vessels in the retina, which are characteristic of wet AMD. By blocking VEGF, Beovu helps to reduce the growth of these abnormal blood vessels and prevent further damage to the retina, ultimately preserving vision in patients with wet AMD.

How should this medicine be used?

Beovu (brolucizumab) is typically administered as an injection into the eye by a healthcare professional. Here’s how it’s typically used:

  • Preparation: The healthcare provider will first prepare the injection and sterilize the area around your eye to reduce the risk of infection.
  • Administration: You will be seated comfortably, and the healthcare provider will use a specialized tool to hold your eyelids open. They will then carefully administer the Beovu injection into the eye. This process is usually quick and relatively painless.
  • Post-injection care: After the injection, your eye may be sensitive or irritated for a short time. You may be given eye drops or other medications to help alleviate any discomfort and prevent infection. It’s essential to follow any post-injection care instructions provided by your healthcare provider.
  • Follow-up appointments: Depending on your treatment plan, you may need to return for additional Beovu injections at regular intervals. Your doctor will monitor your progress and adjust your treatment as needed.

It’s crucial to follow your doctor’s instructions carefully regarding the use of Beovu. Never attempt to administer the injection yourself unless you have been trained to do so by a healthcare professional. If you have any questions or concerns about how to use Beovu or its potential side effects, be sure to discuss them with your doctor.

Other uses for this medicine

Beovu (brolucizumab) is primarily used for the treatment of wet age-related macular degeneration (AMD). While its primary use is for this condition, there may be ongoing research exploring its potential effectiveness for other eye diseases or conditions involving abnormal blood vessel growth in the eye.

What special precautions should I follow?

Regarding special precautions for using Beovu, it’s crucial to follow your doctor’s guidance closely. Here are some general precautions to keep in mind:

  • Inform your doctor about your medical history: Before starting Beovu treatment, inform your doctor about any medical conditions you have, especially if you have a history of eye infections or inflammation.
  • Allergic reactions: Beovu can cause allergic reactions in some people. Inform your doctor if you have had any allergic reactions to Beovu or any other medications in the past.
  • Eye infections: Beovu injections carry a risk of eye infections. Inform your doctor if you have any signs of an eye infection, such as redness, swelling, or discharge, after receiving an injection.
  • Monitoring: Your doctor will monitor your eye health closely during Beovu treatment. Regular eye examinations are essential to monitor for any changes in your vision or the health of your eye.
  • Pregnancy and breastfeeding: It’s essential to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Beovu during pregnancy and breastfeeding has not been established.
  • Other medications: Inform your doctor about any other medications, supplements, or herbal remedies you are taking, as they may interact with Beovu.
  • Driving and operating machinery: Beovu may cause temporary changes in vision, so it’s essential to use caution when driving or operating machinery until you know how it affects you.

Always follow your doctor’s instructions carefully and report any unusual symptoms or side effects promptly. Your doctor can provide personalized guidance based on your individual health status and medical history.

What special dietary instructions should I follow?

There are typically no specific dietary instructions associated with Beovu. However, maintaining a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support overall health and may contribute to eye health.

What should I do if I forget a dose?

If you miss a scheduled dose of Beovu, contact your healthcare provider to reschedule the appointment. It’s essential to maintain the recommended dosing schedule to ensure the effectiveness of treatment. Do not attempt to administer the injection yourself or adjust the dosing schedule without consulting your healthcare provider.

What side effects can this medication cause?

Beovu (brolucizumab) can cause side effects, some of which may be serious. It’s essential to be aware of these potential side effects and to contact your healthcare provider if you experience any symptoms. Common side effects of Beovu may include:

  • Eye Irritation: After receiving an injection, you may experience temporary irritation, redness, or discomfort in the eye.
  • Floaters: Some people may notice the appearance of floaters or specks in their vision after Beovu treatment.
  • Blurry Vision: Temporary changes in vision, including blurry vision, may occur after receiving Beovu injections.
  • Eye Pain: Some individuals may experience mild to moderate eye pain or discomfort after treatment.
  • Increased Eye Pressure: Beovu injections may lead to an increase in intraocular pressure (pressure inside the eye) in some individuals.
  • Conjunctival Hemorrhage: Redness or bleeding on the white part of the eye (conjunctiva) may occur in some cases.
  • Eye Inflammation: Beovu can cause inflammation in the eye, leading to symptoms such as redness, swelling, and pain.
  • Eye Infections: There is a risk of developing eye infections, including endophthalmitis, after Beovu injections. Symptoms of eye infection may include pain, redness, discharge, and vision changes.
  • Allergic Reactions: In rare cases, Beovu can cause allergic reactions, which may manifest as rash, itching, swelling, severe dizziness, or difficulty breathing.
  • Retinal Detachment: Although uncommon, retinal detachment can occur as a complication of Beovu treatment.

It’s essential to report any side effects or symptoms to your healthcare provider promptly. They can assess your condition and provide appropriate management or adjustment of your treatment plan. Additionally, if you experience severe or concerning symptoms, seek medical attention immediately.

What should I know about storage and disposal of this medication?

Storage and Disposal:

  • Storage: Beovu should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Keep the medication in its original carton to protect it from light. Do not freeze Beovu. Once removed from the refrigerator, Beovu can be kept at room temperature (up to 25°C or 77°F) for up to 8 hours. If not used within 8 hours, discard the medication.
  • Disposal: Unused or expired Beovu should be disposed of properly according to local regulations. Do not dispose of Beovu in household trash or wastewater. Consult your healthcare provider or pharmacist for guidance on proper disposal methods.

In case of emergency/overdose

In case of an emergency or overdose involving Beovu, seek medical attention immediately. Symptoms of an overdose may include severe eye pain, vision changes, or other serious adverse reactions. It’s essential to contact your healthcare provider or local poison control center for guidance in managing the overdose situation.

What other information should I know?

  • Injection Site Reactions: After receiving Beovu injections, you may experience temporary discomfort or irritation at the injection site. This is normal and typically resolves on its own. However, if you experience persistent or severe pain, redness, or swelling at the injection site, notify your healthcare provider.
  • Follow-Up Care: Attend all scheduled follow-up appointments with your healthcare provider for monitoring of your eye health and response to treatment. Your doctor may recommend additional tests or examinations to assess the effectiveness of Beovu therapy.
  • Travel: If you need to travel with Beovu, ensure proper storage of the medication to maintain its efficacy. Consider using a portable cooler or insulated bag to keep Beovu at the appropriate temperature during travel.
  • Patient Information Leaflet: Be sure to read and understand the patient information leaflet provided with Beovu. It contains important instructions and safety information about the medication.
  • Communication: Keep an open line of communication with your healthcare provider regarding any questions, concerns, or changes in your health status while using Beovu. They can provide personalized guidance and support throughout your treatment journey.

By adhering to these guidelines and staying informed about Beovu, you can maximize the benefits of treatment while minimizing the risks associated with its use.

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