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Benzamycin (Generic Erythromycin and Benzoyl Peroxide Topical)

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Why is this medication prescribed?

Erythromycin and Benzoyl Peroxide Topical is typically prescribed for the treatment of acne. Erythromycin is an antibiotic that helps to kill the bacteria associated with acne, while benzoyl peroxide works as an antimicrobial agent and also helps to reduce inflammation.

How should this medicine be used?

Here’s how it’s generally used:

  • Clean the affected area: Wash the affected skin area with a mild cleanser and pat it dry before applying the medication. This helps to remove excess oil, dirt, and impurities from the skin.
  • Apply a thin layer: Apply a thin layer of the Erythromycin and Benzoyl Peroxide Topical medication to the affected areas. Be sure to apply it evenly, covering the entire affected area, not just individual pimples.
  • Frequency of application: The frequency of application will depend on your doctor’s instructions and the severity of your acne. It’s typically applied once or twice daily.
  • Avoid contact with eyes, mouth, and mucous membranes: Be careful to avoid getting the medication in your eyes, mouth, or other mucous membranes, as it may cause irritation.
  • Follow your doctor’s instructions: It’s important to follow your doctor’s instructions carefully when using this medication. They may adjust the dosage or frequency of application based on your individual needs and response to treatment.
  • Be patient: Acne treatments often take time to show results, so be patient and consistent with your application of Erythromycin and Benzoyl Peroxide Topical. It may take several weeks to see improvement in your acne.
  • Monitor for side effects: Keep an eye out for any potential side effects such as redness, irritation, or dryness of the skin. If you experience any severe or persistent side effects, be sure to consult your doctor.

Remember, while Erythromycin and Benzoyl Peroxide Topical can be effective for treating acne, it’s important to use it as directed and to follow up with your doctor regularly to monitor your progress and adjust your treatment plan as needed.

Other uses for this medicine

Some potential off-label uses may include:

  • Treatment of certain skin infections caused by bacteria sensitive to erythromycin.
  • Management of folliculitis (inflammation of hair follicles).
  • Adjunctive therapy for rosacea.

What special precautions should I follow?

Regarding special precautions, here are some important points to keep in mind when using Erythromycin and Benzoyl Peroxide Topical:

  • Allergy: Inform your doctor if you have a known allergy to erythromycin, benzoyl peroxide, or any other ingredients in the medication. Allergic reactions may include rash, itching, swelling, dizziness, or difficulty breathing, and require immediate medical attention.
  • Avoid sensitive areas: Be cautious when applying the medication near sensitive areas such as the eyes, mouth, nose, and mucous membranes. Avoid contact with these areas, as irritation or adverse effects may occur.
  • Sun sensitivity: Benzoyl peroxide can make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing to minimize sun exposure while using this medication.
  • Avoid excessive use: Using more medication than prescribed or applying it more frequently than directed will not improve your acne faster and may increase the risk of side effects. Follow your doctor’s instructions carefully.
  • Avoid concurrent use of other acne medications: Unless directed by your doctor, avoid using other topical acne medications or products containing high concentrations of alcohol, astringents, or abrasive agents, as they may increase skin irritation.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Erythromycin and Benzoyl Peroxide Topical with your healthcare provider before starting treatment.
  • Consultation with healthcare provider: Always consult your doctor or dermatologist before starting or stopping any medication, including topical treatments for acne. They can provide personalized advice based on your medical history and individual circumstances.

By following these precautions and guidelines, you can maximize the effectiveness of Erythromycin and Benzoyl Peroxide Topical while minimizing the risk of adverse effects.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with using Erythromycin and Benzoyl Peroxide Topical. However, maintaining a healthy diet and staying hydrated can contribute to overall skin health.

What should I do if I forget a dose?

If you forget to apply a dose of Erythromycin and Benzoyl Peroxide Topical, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for the missed dose, as this can increase the risk of side effects. If you have any concerns or questions about missed doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Erythromycin and Benzoyl Peroxide Topical, like any medication, can cause side effects, although not everyone experiences them. Common side effects may include:

  • Skin irritation: This is the most common side effect and may include redness, dryness, itching, burning, or peeling of the skin at the application site.
  • Allergic reactions: Some individuals may experience allergic reactions to either erythromycin or benzoyl peroxide, which can manifest as rash, hives, itching, swelling, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.
  • Discoloration of skin or hair: Benzoyl peroxide may cause temporary discoloration of the skin or hair, especially in individuals with darker skin tones.
  • Sun sensitivity: Benzoyl peroxide can increase the skin’s sensitivity to sunlight, leading to a greater risk of sunburn. It’s important to use sunscreen and protective clothing while using this medication.
  • Dryness: Benzoyl peroxide can cause dryness of the skin, particularly during the initial stages of treatment.
  • Peeling: Some individuals may experience mild peeling of the skin, especially in areas where the medication is applied.
  • Erythema: Redness of the skin, particularly at the site of application, may occur in some individuals.
  • Contact dermatitis: Rarely, individuals may develop contact dermatitis, which is characterized by redness, itching, and inflammation of the skin due to a reaction to the medication.

It’s essential to monitor your skin for any signs of irritation or adverse reactions while using Erythromycin and Benzoyl Peroxide Topical. If you experience severe or persistent side effects, or if you have any concerns, contact your healthcare provider for further guidance. They may recommend adjusting your treatment regimen or prescribing alternative medications.

What should I know about storage and disposal of this medication?

When it comes to storing and disposing of Erythromycin and Benzoyl Peroxide Topical, here’s what you should know:


  • Store at room temperature: Keep Erythromycin and Benzoyl Peroxide Topical at room temperature, away from moisture and heat. Avoid storing it in the bathroom, as moisture can affect the medication’s stability.
  • Keep out of reach of children: Store the medication in a secure location where children and pets cannot access it.
  • Protect from light: Some medications may degrade when exposed to light, so it’s best to store Erythromycin and Benzoyl Peroxide Topical in its original container, away from direct sunlight or bright light.
  • Do not freeze: Avoid freezing the medication, as this can alter its effectiveness.


  • Follow disposal instructions: Dispose of any unused or expired Erythromycin and Benzoyl Peroxide Topical according to your local regulations or the instructions provided by your healthcare provider or pharmacist.
  • Do not flush: Do not flush unused medication down the toilet or pour it down the drain unless instructed to do so. This helps to prevent environmental contamination.
  • Use medication disposal programs: Some communities offer medication disposal programs or take-back events where you can safely dispose of unused medications. Check with your local pharmacy or health department for information on disposal options in your area.

In case of emergency/overdose

In case of emergency or accidental ingestion of Erythromycin and Benzoyl Peroxide Topical, contact your local poison control center (in the United States, call 1-800-222-1222) or seek emergency medical attention immediately. Be prepared to provide information about the medication ingested, the amount taken, and any symptoms experienced.

What other information should I know?

  • Follow instructions: Always use Erythromycin and Benzoyl Peroxide Topical exactly as prescribed by your healthcare provider. Do not use more or less of it or use it more frequently than directed.
  • Avoid sharing: Do not share Erythromycin and Benzoyl Peroxide Topical with others, even if they have similar symptoms. This medication is prescribed based on individual needs and should not be used by anyone else.
  • Regular follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your progress and adjust your treatment plan as needed.
  • Inform healthcare providers: Inform all healthcare providers involved in your care, including doctors, dentists, and pharmacists, about all the medications you are taking, including prescription, over-the-counter, and herbal supplements.

By following these guidelines, you can ensure the safe and effective use of Erythromycin and Benzoyl Peroxide Topical for the treatment of acne. If you have any questions or concerns, don’t hesitate to consult your healthcare provider or pharmacist for guidance.

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