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Benazepril and Hydrochlorothiazide

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If you are pregnant, avoid using hydrochlorothiazide and benazepril. Call your doctor right away if you get pregnant while taking hydrochlorothiazide and benazepril. The foetus may be harmed by benazepril and hydrochlorothiazide.

Why is this medication prescribed?

Benazepril and hydrochlorothiazide are taken together to treat high blood pressure. Benazepril belongs to the angiotensin-converting enzyme (ACE) inhibitors drug class. It functions by lowering specific molecules that stiffen blood arteries, allowing blood to flow more freely. Diuretics, also known as “water pills,” are a class of drugs that includes hydrochlorothiazide. It functions by causing the kidneys to excrete salt and water from the body through the urine.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

Benazepril and hydrochlorothiazide are packaged as a tablet for oral use. Typically, it is given once day. Benazepril and hydrochlorothiazide should be taken at roughly the same time each day to help you remember to take them. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Benazepril and hydrochlorothiazide should be taken exactly as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Although they can help manage high blood pressure, benazepril and hydrochlorothiazide do not cure it. Even if you feel better, keep taking hydrochlorothiazide and benazepril. Without consulting your doctor, never discontinue taking hydrochlorothiazide or benazepril.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking benazepril and hydrochlorothiazide,

  • Angiotensin-converting enzyme (ACE) inhibitors such as captopril (Capoten), enalapril (Vasotec, in Vaseretic), fosinopril (Monopril), and lisinopril should be avoided if you are allergic to benazepril (Lotensin), hydrochlorothiazide (HCTZ, Microzide, Oretic), or benazepril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); sulfa drugs; any other medicines; any other medicines; or any components of the tablets containing benazepril and hydrochlorothiazide Request a list of the components from your pharmacist.
  • If you are currently using valsartan and sacubitril (Entresto), or if you have just stopped taking it, let your doctor or pharmacist know. If you are also taking valsartan and sacubitril, your doctor will likely advise you to avoid taking benazepril and hydrochlorothiazide. Additionally, let your physician know if you have diabetes and are on aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). If you have diabetes and are also on aliskiren, your doctor generally won’t let you take benazepril plus hydrochlorothiazide.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Mention any of the following: aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), cholestyramine (Prevalite), colestipol (Colestid), insulin, lithium (Lithobid), oral steroids like dexamethasone, methylprednisolone (Medrol), and prednisone (Ray Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • In addition, let your doctor know if you have or have previously had allergies, asthma, heart failure, diabetes, gout, high cholesterol, lupus, scleroderma, renal disease, or liver illness.
  • Describe to your doctor if you are nursing a baby.
  • Inform the surgeon or dentist that you are taking hydrochlorothiazide and benazepril if you are having surgery, including dental surgery.
  • You should be aware that a reduction in blood pressure might result from diarrhoea, vomiting, dehydration, and excessive perspiration, which can make you feel faint and dizzy.

What special dietary instructions should I follow?

Before using potassium-containing salt replacements, consult your doctor. If your doctor advises a low-salt or low-sodium diet or an exercise regimen, pay close attention to the instructions.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Both hydrochlorothiazide and benazepril may have negative side effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Cough
  • Dizziness
  • Extreme exhaustion
  • Drowsiness

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

  • Edoema of the hands, feet, ankles, lower legs, cheeks, neck, tongue, lips, and eyes
  • Hoarseness
  • Breathing or swallowing challenges
  • Rash
  • Lightheadedness
  • Fainting
  • Infection symptoms such a fever, sore throat, chills, and others
  • Eyes or skin that have a yellow tint
  • Mouth ache
  • Thirst
  • Weakness
  • Not enough energy
  • Restlessness
  • Cramping or aching muscles
  • Sporadic urination
  • Uneasy stomach
  • Vomiting
  • Irregular, hammering, or quick heartbeat

Other adverse effects from benazepril and hydrochlorothiazide are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. You should monitor your blood pressure frequently to see how benazepril and hydrochlorothiazide affect you. To determine how your body is responding to benazepril and hydrochlorothiazide, your doctor may request specific lab tests.

Inform the lab staff and your doctor that you are taking hydrochlorothiazide and benazepril prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Lotensin® HCT
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