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Baxdela (Generic Delafloxacin Injection)

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Delafloxacin injection is an antibiotic used to treat certain bacterial infections. Like all medications, it carries risks and potential side effects. Some common risks associated with delafloxacin injection include:

  • Allergic reactions: Some people may experience allergic reactions, ranging from mild rash to severe allergic reactions that can be life-threatening.
  • Gastrointestinal effects: Delafloxacin may cause nausea, vomiting, diarrhea, or abdominal pain in some individuals.
  • Central nervous system effects: Headache, dizziness, and confusion are potential side effects of delafloxacin injection.
  • Tendon effects: There is a risk of tendonitis or tendon rupture, particularly in older adults or those who are on corticosteroid therapy.
  • Photosensitivity: Delafloxacin may increase sensitivity to sunlight, leading to sunburn more easily.
  • Clostridium difficile infection: Antibiotic use can disrupt the balance of bacteria in the gut and increase the risk of Clostridium difficile infection, which can cause severe diarrhea and colitis.
  • Liver effects: In some cases, delafloxacin can cause liver damage or abnormal liver function tests.

It’s important to discuss any concerns or potential risks with your healthcare provider before starting delafloxacin injection or any other medication.

Why is this medication prescribed?

Delafloxacin injection is typically prescribed to treat acute bacterial skin and skin structure infections (ABSSSI), including those caused by methicillin-resistant Staphylococcus aureus (MRSA). It’s an antibiotic medication that belongs to the fluoroquinolone class.

How should this medicine be used?

The dosage and administration of delafloxacin injection can vary depending on the severity of the infection, the patient’s age, weight, and overall health. Generally, it’s administered intravenously (IV) over a specified period as directed by a healthcare professional.

It’s important to follow the dosage and administration instructions provided by your healthcare provider or pharmacist carefully. Additionally, it’s crucial to complete the full course of treatment, even if symptoms improve before the medication is finished, to prevent the recurrence of infection and the development of antibiotic resistance.

As with any medication, it’s essential to discuss any questions or concerns about delafloxacin injection with your healthcare provider. They can provide personalized advice based on your specific medical condition and history

Other uses for this medicine

Delafloxacin is primarily indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible bacteria. However, healthcare providers may sometimes prescribe it for other bacterial infections if they believe it is appropriate and effective. Always follow your doctor’s instructions regarding the use of Delafloxacin Injection.

What special precautions should I follow?

As for special precautions when using delafloxacin injection, it’s essential to consider the following:

  • Allergies: Inform your healthcare provider if you have any known allergies to delafloxacin or other fluoroquinolone antibiotics.
  • Pregnancy and breastfeeding: Consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They can weigh the potential risks and benefits of delafloxacin injection for you and your baby.
  • Drug interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, as they may interact with delafloxacin and affect its effectiveness or increase the risk of side effects.
  • Tendon damage: Fluoroquinolone antibiotics, including delafloxacin, have been associated with an increased risk of tendonitis and tendon rupture, particularly in older adults, those taking corticosteroids, and those with a history of tendon disorders. Exercise caution and inform your healthcare provider if you experience any tendon pain or swelling during treatment.
  • Central nervous system effects: Delafloxacin may cause central nervous system side effects such as dizziness, headache, and confusion. Use caution when driving or operating machinery until you know how the medication affects you.
  • Clostridium difficile-associated diarrhea: Antibiotic use, including delafloxacin, may lead to the overgrowth of bacteria called Clostridium difficile, which can cause severe diarrhea and colitis. Inform your healthcare provider if you experience persistent diarrhea during or after treatment.

Always follow your healthcare provider’s instructions and advice regarding the use of delafloxacin injection, and do not hesitate to ask any questions or express concerns you may have about the medication.

What special dietary instructions should I follow?

Regarding special dietary instructions for delafloxacin injection, it can generally be taken with or without food. However, it’s essential to follow your healthcare provider’s specific instructions regarding food and drink while using this medication, as they may provide personalized advice based on your individual needs and medical condition.

What should I do if I forget a dose?

If you forget to take a dose of delafloxacin injection, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. If you have any questions or concerns about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Delafloxacin injection, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Some common side effects of delafloxacin injection may include:

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Vomiting
  • Injection site reactions (such as pain, redness, or swelling)
  • Rash or itching

Less common but more serious side effects may also occur. These can include:

  • Allergic reactions, including anaphylaxis (a severe allergic reaction that requires immediate medical attention)
  • Tendonitis or tendon rupture
  • Clostridium difficile-associated diarrhea (potentially severe diarrhea caused by a bacterial infection)
  • Central nervous system effects, such as confusion, hallucinations, or seizures
  • Changes in blood sugar levels (especially in patients with diabetes)
  • Liver problems, including abnormal liver function tests or liver failure
  • Photosensitivity (increased sensitivity to sunlight)

If you experience any severe or persistent side effects while using delafloxacin injection, contact your healthcare provider immediately. It’s important to report any side effects to your healthcare provider or pharmacist, as they can provide guidance and determine whether any adjustments to your treatment plan are necessary. If you experience a medical emergency, such as difficulty breathing or severe allergic reactions, seek immediate medical attention.

Additionally, it’s essential to discuss your medical history and any potential risk factors with your healthcare provider before starting treatment with delafloxacin injection. This can help minimize the risk of side effects and ensure the safe and effective use of the medication.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of delafloxacin injection, here’s what you should know:


  • Store delafloxacin injection at room temperature, away from moisture and heat.
  • Do not freeze the medication.
  • Keep it out of the reach of children and pets.
  • Follow any specific storage instructions provided by your healthcare provider or pharmacist.


  • Dispose of any unused delafloxacin injection properly according to local regulations or guidelines.
  • Do not flush the medication down the toilet or pour it down the drain unless instructed to do so.
  • Consult your pharmacist or local waste disposal facility for information on how to dispose of delafloxacin injection safely.

In case of emergency/overdose

In case of emergency or overdose of delafloxacin injection, it’s important to seek immediate medical attention or contact a poison control center (such as the National Poison Control Center at 1-800-222-1222 in the United States). Be prepared to provide information about the medication, the dosage taken (if known), and any symptoms experienced.

What other information should I know?

  • Keep all appointments with your healthcare provider for follow-up evaluations during and after treatment.
  • Do not share delafloxacin injection with others, even if they have similar symptoms, as it may not be suitable for their condition.
  • Complete the full course of treatment prescribed by your healthcare provider, even if you start to feel better before the medication is finished.
  • Avoid prolonged exposure to sunlight or artificial UV rays while using delafloxacin injection, as it may increase the risk of sunburn or skin reactions.
  • Inform your healthcare provider if you develop any new or worsening symptoms while using delafloxacin injection, as they may indicate a potential complication or adverse reaction.

By following these guidelines and staying informed about delafloxacin injection, you can help ensure its safe and effective use for the treatment of bacterial infections.

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