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Basiliximab Injection

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Basiliximab injection should only be administered in a hospital or clinic under the guidance of a physician with experience managing transplant patients and writing prescriptions for drugs that suppress the immune system.

Why is this medication prescribed?

When getting kidney transplants, basiliximab injection is used with other drugs to prevent early transplant rejection (the immune system of the recipient’s body attacking the donated organ). Immunosuppressants are a family of medicines that includes basiliximab injection. It functions by lowering immune system activity so that the body won’t fight the transplanted organ.

How should this medicine be used?

In a hospital or other medical facility, a doctor or nurse will provide basiliximab injection intravenously (into a vein) using a powder that has been combined with water. Usually, 2 dosages are administered. The first dose is typically administered two hours prior to the transplant operation, and the second dose is typically administered four days later.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving basiliximab injection,

  • If you have any allergies, including to basiliximab injection, other drugs, or any of the chemicals in basiliximab injection, notify your doctor right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you currently have, or have previously had, any medical conditions, and if you have ever received basiliximab injectable treatment.
  • If you are pregnant or plan to become pregnant, let your doctor know. Getting pregnant while getting basiliximab injections is not advised. Before starting your therapy, during your treatment, and for four months after your treatment, discuss birth control options with your doctor.
  • Inform your doctor if you are nursing a baby.
  • Avoid getting any shots without first consulting your doctor.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

The injection of basiliximab may have unwanted effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Heartburn
  • Edoema of the lower legs, ankles, feet, or hands
  • Clogged nose
  • Headache
  • Region of your body that you are unable to control shakes
  • Having trouble falling or staying asleep
  • Suffering from discomfort at the injection site

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

  • Hives
  • Rash
  • Itching
  • Sneezing
  • Cough
  • Wheezing
  • Breathing or swallowing challenges
  • Rapid heart rate
  • Muscular pain
  • Fatigue
  • Dizziness, lightheadedness, or fainting
  • Edoema throughout the body and increased weight
  • Fever, chills, or other symptoms of illness in addition to a sore throat
  • Uncomfortable or challenging urinating
  • Less urinations

The chance of contracting an infection or cancer may rise after receiving a basiliximab injection. The dangers of using this drug should be discussed with your doctor.

Other negative effects from basiliximab injection could also occur. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Inquire about basiliximab injection with your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Simulect®
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