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Basaglar (Generic Insulin Glargine (rDNA origin) Injection)

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Why is this medication prescribed?

Products containing insulin glargine are used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). People who require insulin to regulate their type 2 diabetes (a condition in which the body does not utilise insulin normally and cannot control the quantity of sugar in the blood) can also be treated with insulin glargine products. Products containing insulin glargine must be used with another insulin type in patients with type 1 diabetes (a short-acting insulin). Products containing insulin glargine may also be combined with another type of insulin or with oral diabetic medications in persons with type 2 diabetes. A synthetic, long-acting alternative to human insulin is insulin glargine. Products containing insulin glargine function by substituting for the insulin that the body typically produces and by assisting in the transfer of blood sugar to other body tissues where it is utilised as an energy source. The liver’s ability to produce additional sugar is likewise inhibited.

People with diabetes and high blood sugar over time may experience serious or fatal complications, such as heart disease, stroke, kidney issues, nerve damage, and vision issues. It may be possible to control your diabetes and enhance your health by using medication(s), making lifestyle changes (such as diet, exercise, and quitting smoking), and routinely checking your blood sugar. This treatment may also lower your risk of heart attack, stroke, kidney failure, nerve damage (resulting in numb, cold legs or feet and diminished sex capacity in both men and women), eye issues, such as changes in eyesight or blindness, or gum disease, which are all symptoms of diabetes. The optimal strategy to manage your diabetes will be discussed with you by your doctor and other healthcare professionals.

How should this medicine be used?

Products containing insulin glargine are available as liquid solutions to inject subcutaneously (under the skin). Each day, they receive an injection. Products containing insulin glargine should be taken at the same time each day. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Use goods containing insulin glargine exactly as instructed. Use it only as directed by your doctor, neither more nor less often.

When experiencing hypoglycemia (low blood sugar) symptoms or after checking your blood sugar and finding it to be low, never use insulin glargine products.

Diabetes cannot be cured, but insulin glargine products can manage it. Even if you feel good, keep using insulin glargine products. Without consulting your doctor, never discontinue using insulin glargine products. Without first seeing your doctor, never modify the dose of any type of insulin you are now receiving or switch to a different brand. Make sure you always read the insulin label to ensure you got the proper kind of insulin from the pharmacy.

Products for administering insulin glargine are offered in vials and dosing pens with medicine cartridges. Make sure you are aware of the sort of container your insulin glargine product comes in as well as any additional equipment, such as needles, syringes, or injection pens, that may be required.

You will need syringes to administer your dose if the insulin glargine product you are using is packaged in vials. Request instruction on using a syringe to administer insulin glargine from your physician or pharmacist. If you have any concerns about the kind of syringe you ought to use, consult your physician or pharmacist.

Make sure you read and comprehend the manufacturer’s instructions if the insulin glargine product you’re using comes in pens. You can get the pen’s instructions from your doctor or pharmacist. Always carry out the safety test before use, and pay close attention to the instructions.

Never share needles, syringes, or pens, and never reuse needles or syringes. Always take out the needle from an insulin pen as soon as you’ve finished injecting your dose. Put used needles and syringes in a container that won’t puncture. For disposal instructions on the puncture-resistant container, consult your doctor or pharmacist.

Products containing insulin glargine should not be diluted or used with any other insulin.

Insulin glargine injection sites include the upper arm, thigh, and stomach. Never administer glargine insulin into a vein or muscle. Avoid injecting into areas of skin that are thick, lumpy, painful, bruised, scaly, or hard, or where there are scars or other signs of skin injury. With each dose, switch (rotate) the injection site within the targeted area; avoid using the same location more frequently than once every one to two weeks.

To ensure you are taking the right insulin, always read the label on your insulin glargine product and inspect it before injecting. It need to be transparent and colourless. If the insulin glargine product has beyond its expiration date, is coloured, foggy, or includes solid particles, do not use it.

Products containing insulin glargine shouldn’t be used in external insulin pumps.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using insulin glargine products,

  • Inform your doctor and pharmacist if you have any allergies to any of the substances in insulin glargine products, including insulin (Humulin, Novolin, and other brands). Request a list of the components from your pharmacist.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking. Make careful to specify rosiglitazone and pioglitazone (Actos, in Actoplus Met, in Duetact, in Oseni) (Avandia). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your physician if you have or have ever had nerve damage brought on by diabetes, heart failure, low potassium levels in the blood, eyesight issues, or any other health issues with the heart, liver, or kidney disease.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while using an insulin glargine product.
  • Inform the surgeon or dentist that you are using an insulin glargine product if you are having surgery, including dental surgery.
  • Alcohol may alter blood sugar levels. Consult your doctor about whether drinking alcohol is safe while taking an insulin glargine medication.
  • In the event that you become ill, encounter extraordinary stress, or alter your diet, exercise routine, or daily schedule, consult your doctor for advice. Your blood sugar levels and the amount of insulin you may require may be impacted by these changes.
  • Find out from your physician how frequently you should check your blood sugar. You should be aware that hypoglycemia can impair your ability to do activities like driving, so check with your doctor if you need to check your blood sugar before you drive or operate machinery.

What special dietary instructions should I follow?

Make sure to abide by all dietary and exercise advice given to you by your physician or nutritionist. It is crucial to follow a healthy diet and eat around the same portions of the same foods at roughly the same times every day. Your ability to control your blood sugar levels may suffer if you skip or delay meals, change the quantity or type of food you eat, or all three.

What should I do if I forget a dose?

Ask your doctor what to do if you mistakenly use an additional dose of insulin glargine or forget to take a dose before you begin using the medication. To remember these instructions later, write them down.

What side effects can this medication cause?

Your blood sugar levels may alter as a result of this drug. You should be aware of the signs of low and high blood sugar as well as what to do if you experience these signs.

Products containing insulin glargine may have adverse effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • An injection site with redness, swelling, discomfort, or itching
  • Alterations in how your skin feels, skin thickening (due to fat buildup), or a slight skin depression (fat breakdown)
  • Fever, cough, sore throat, or other infection-related symptoms

Some adverse effects can be very harmful. Call your doctor right away if you encounter these symptoms, or seek emergency care:

  • Body itching, hives, or a rash everywhere
  • Wheezing
  • Breathing or swallowing challenges
  • Rapid heartbeat
  • Sweating
  • Enlargement of the throat, lips, tongue, eyes, or face
  • Hoarseness
  • Weakness
  • Muscular pain
  • Irregular heartbeat
  • Unexpected weight gain
  • Edoema in the foot or ankles
  • Breathing difficulty
  • Vision alterations

Other adverse effects from insulin glargine products are possible. If you experience any strange issues while taking this drug, call your doctor right away.

What should I know about storage and disposal of this medication?

Keep this medication out of the reach of children and in the original container. Vials and pens for insulin glargine products should be kept in the refrigerator until use. Never let items containing insulin glargine freeze, and never use thawed-frozen insulin glargine. Refrigerated insulin glargine goods that have not been opened can be kept until the date printed on the manufacturer’s label.

Keep the vials or pens at room temperature, away from strong sunlight, and from high heat if a refrigerator is not accessible (as might be the case when on vacation). Vials or pens that are not refrigerated can only be used for a total of 28 days before being thrown. Vials that have been opened can be kept for 28 days in the refrigerator or at room temperature. After the first usage, opened pens can be used for up to 28 days if they are kept at room temperature. Any insulin that has been subjected to excessive cold or heat should be disposed of.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Insulin glargine overload can happen if you use too much of it, the proper dosage, but consume less food than normal or exercise more than usual. Hypoglycemia may result from an overdose of insulin glargine. Follow your doctor’s recommendations on what to do if you experience hypoglycemia if you have symptoms. Other overdose signs include:

  • Loss of consciousness
  • Seizures

What other information should I know?

Keep all of your appointments with your physician and the lab. You should check your blood sugar and glycosylated haemoglobin (HbA1c) frequently to see how well you’re responding to insulin glargine. Your doctor will also instruct you on how to measure your blood sugar levels at home in order to monitor your reaction to this medicine. Pay close attention to these directions.

Wearing a diabetes identity bracelet will ensure that you receive the right care in an emergency.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Basaglar®
  • Lantus®
  • Rezvoglar® (Insulin Glargine-aglr)
  • Semglee® (Insulin Glargine-yfgn)
  • Toujeo®
  • Soliqua® (as a combination product containing Insulin Glargine and Lixisenatide),
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