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Bactroban Nasal (Generic Mupirocin)

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Why is this medication prescribed?

Bactroban Nasal is prescribed for the eradication of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA), a type of bacteria that is resistant to certain antibiotics and can cause infections. It’s commonly used in patients undergoing elective surgery or in healthcare workers who may be at higher risk of MRSA colonization.

How should this medicine be used?

Here’s how Bactroban Nasal is typically used:

  • Wash Hands: Before applying Bactroban Nasal, it’s important to wash your hands thoroughly with soap and water.
  • Prepare the Tube: Remove the protective cap from the Bactroban Nasal tube. Squeeze the sides of the tube gently to apply a small amount of the ointment onto a cotton-tipped applicator.
  • Apply to Nostrils: Using the cotton-tipped applicator, apply a small amount of the ointment inside each nostril. It’s usually applied twice daily for five days.
  • Avoid Contact: Try to avoid touching the inside of your nose with your fingers to prevent spreading bacteria or infection.
  • Finish the Course: Even if symptoms improve before the five-day treatment period is over, it’s important to complete the full course of treatment as prescribed by your healthcare provider.
  • Dispose of Applicator: After each use, dispose of the cotton-tipped applicator properly.
  • Storage: Store Bactroban Nasal at room temperature, away from moisture and heat.

Always follow your healthcare provider’s instructions and read the patient information leaflet provided with the medication for specific guidance on its use and any potential side effects. If you have any questions or concerns about using Bactroban Nasal, don’t hesitate to consult your doctor or pharmacist.

Other uses for this medicine

Some off-label uses may include:

  • Prevention of infections: Bactroban Nasal might be used to prevent infections in certain high-risk individuals, such as those undergoing surgery.
  • Treatment of nasal infections: In some cases, healthcare providers may prescribe Bactroban Nasal to treat nasal infections caused by susceptible bacteria.

What special precautions should I follow?

As for special precautions when using Bactroban Nasal:

  • Allergies: Inform your healthcare provider if you have any known allergies to mupirocin, polyethylene glycol (an ingredient in the ointment), or any other medications.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Bactroban Nasal with your healthcare provider.
  • Medical conditions: Inform your healthcare provider about any medical conditions you have, especially if you have kidney problems or any other underlying health issues.
  • Avoiding contact with eyes: Bactroban Nasal is for use inside the nostrils only. Avoid getting it into your eyes, mouth, or on mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Resistance: Prolonged or repeated use of Bactroban Nasal may result in the growth of resistant bacteria. Follow your healthcare provider’s instructions carefully and do not use it longer than prescribed.
  • Sharing: Do not share Bactroban Nasal with others, even if they have similar symptoms. It’s prescribed specifically for individual use.

Always adhere to your healthcare provider’s recommendations and consult them if you have any questions or concerns about using Bactroban Nasal. They can provide personalized guidance based on your medical history and current health status.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are typically no specific dietary restrictions associated with Bactroban Nasal. However, it’s always a good idea to follow a balanced diet and stay hydrated, as maintaining overall health can support the effectiveness of any treatment.

What should I do if I forget a dose?

If you forget to apply a dose of Bactroban Nasal, apply it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Don’t apply extra doses to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Bactroban Nasal, like any medication, may cause side effects, although not everyone experiences them. Common side effects associated with Bactroban Nasal include:

  • Nasal discomfort: This may include irritation, burning, stinging, itching, dryness, or redness in the nose.
  • Headache: Some individuals may experience mild to moderate headaches while using Bactroban Nasal.
  • Unpleasant taste or smell: Bactroban Nasal may cause a temporary change in taste or smell, often described as an unpleasant or metallic taste or smell.
  • Nausea: Some people may feel nauseous while using Bactroban Nasal, although this is less common.
  • Skin reactions: In rare cases, Bactroban Nasal may cause skin reactions, such as rash or itching, especially if the ointment comes into contact with the skin around the nose.
  • Allergic reactions: Although rare, some individuals may experience allergic reactions to Bactroban Nasal, characterized by symptoms such as swelling, itching, redness, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.

It’s essential to report any unusual or persistent side effects to your healthcare provider. They can provide guidance on managing side effects or adjust your treatment plan if necessary. If you have concerns about potential side effects, discuss them with your doctor or pharmacist before starting Bactroban Nasal.

What should I know about storage and disposal of this medication?

Here’s what you should know about the storage and disposal of Bactroban Nasal:


  • Keep Bactroban Nasal at room temperature, away from moisture and heat.
  • Store it in a safe place, out of reach of children and pets.
  • Avoid storing it in the bathroom or near the kitchen sink, where it might be exposed to moisture.


  • Dispose of Bactroban Nasal properly according to local regulations or as instructed by your healthcare provider or pharmacist.
  • Do not flush it down the toilet or pour it down the drain unless instructed to do so.
  • If you have any unused or expired Bactroban Nasal, consult your pharmacist or local waste disposal facility for guidance on safe disposal methods.

In case of emergency/overdose

  • If you suspect an overdose or accidentally ingest Bactroban Nasal, seek emergency medical attention or contact your local poison control center immediately.
  • Be prepared to provide information about the medication, including its name, strength, and how much was ingested or applied.
  • If possible, take the medication packaging or label with you to the emergency room or when contacting poison control.

What other information should I know?

  • Bactroban Nasal is for nasal use only and should not be applied to other parts of the body.
  • Follow your healthcare provider’s instructions carefully regarding the dosage and duration of treatment.
  • Do not use Bactroban Nasal for longer than prescribed or share it with others, as it may lead to antibiotic resistance.
  • Inform your healthcare provider about any other medications, supplements, or herbal products you are taking, as they may interact with Bactroban Nasal.
  • If your symptoms worsen or do not improve after using Bactroban Nasal, contact your healthcare provider for further evaluation and advice.

By following these guidelines, you can safely store, use, and dispose of Bactroban Nasal, and know what to do in case of an emergency or overdose.

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