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Azactam (Generic Aztreonam Injection)

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Why is this medication prescribed?

Aztreonam injection is used to treat bacterial infections in the urinary system, blood, skin, gynaecological, abdominal (stomach area), respiratory tract (including pneumonia and bronchitis), and abdominal (stomach area). Aztreonam injection can be used to prevent infection in the patient before, during, and occasionally for a short while after surgery. Additionally, it is used to stop infections after colorectal surgery. Aztreonam belongs to the group of drugs known as monobactam antibiotics. It eliminates bacteria to work.

Colds, the flu, and other viral infections cannot be treated with antibiotics like aztreonam injection. Antibiotic use that is not necessary increases the likelihood of developing a later infection that is resistant to antibiotic treatment.

How should this medicine be used?

A mixture of liquid and powder is used to administer aztreonam injection intravenously (into a vein) or intramuscularly (into a muscle). Aztreonam is typically infused (slowly injected) over the course of 20 to 1 hour when administered intravenously. Aztreonam is injected intramuscularly into the muscles of the thighs or buttocks. The type of infection you have and how your body reacts to the drug determine how frequently you receive aztreonam injections and how long your therapy will last. How long to administer aztreonam injection will be determined by your doctor. Your doctor can change you to another oral antibiotic after your condition becomes better to finish your therapy.

Aztreonam injection can be obtained in a hospital, or you can take the medicine at home. Your doctor will demonstrate how to administer aztreonam injection if you choose to do so at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

During the first few days of receiving aztreonam injectable therapy, you should start to feel better. Call your doctor if your symptoms do not disappear or worsen.

Even if you feel better, keep using the aztreonam injection until the prescription is finished. Your illness could not be entirely treated if you stop using aztreonam injection too soon or if you miss doses, and the bacteria might develop an antibiotic resistance.

Other uses for this medicine

Aztreonam injection is occasionally used to treat patients with fever who are also at high risk for infection due to low white blood cell counts. The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using aztreonam injection,

  • If you have an allergy to aztreonam, beta-lactam antibiotics like penicillin or amoxicillin (Amoxil, Trimox, Wymox), carbapenem antibiotics like doripenem (Doribax), ertapenem (Invanz), or meropenem (Merrem), any other medications, or any of the ingredients in aztreonam injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are currently taking or intend to take.
  • If you have or have previously had liver or kidney disease, let your doctor know.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you get pregnant while taking aztreonam injection.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

The missed dose should be taken as soon as you remember. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

The injection of aztreonam may have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Bruising, swelling, or redness at the injection site

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Severe diarrhoea (watery or bloody stools), which may or may not be accompanied by fever and cramps in the stomach
  • Hives
  • Itching
  • Rash
  • Breathing or swallowing challenges
  • Skin, mouth, nose, and eye blisters

Other negative effects of aztreonam injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor how your body is responding to the aztreonam injection, your doctor might request specific lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Azactam®
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