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Axert (Generic Almotriptan)

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Why is this medication prescribed?

Almotriptan is used to treat migraine headache symptoms (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Almotriptan is a member of the selective serotonin receptor agonists drug family. It functions by constricting blood arteries surrounding the brain, preventing pain signals from reaching the brain, and preventing the production of several naturally occurring compounds that produce pain, nausea, and other migraine symptoms. Almotriptan does not lessen the frequency of headaches or stop migraine attacks.

How should this medicine be used?

Almotriptan is available as an oral tablet. It is typically given as soon as a migraine headache appears. Take a second tablet if necessary if your symptoms subside after taking almotriptan but return in two hours or more. Don’t take a second tablet of almotriptan before calling your doctor, though, if your symptoms do not get better after taking the medication. The maximum amount of pills you can take in a day will be specified by your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Almotriptan should only be used as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Your first dose of almotriptan may be administered in a doctor’s office or another healthcare facility where you can be watched closely for negative reactions.

If your headaches do not improve or become more frequent after taking almotriptan, contact your doctor right away.

Your headaches may worsen or become more frequent if you use almotriptan more frequently or for a longer duration than is advised. Almotriptan and other headache medications shouldn’t be taken more than ten days a month. If you need to take almotriptan to cure more than four headaches in a month, call your doctor right away.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking almotriptan,

  • If you have an allergy to almotriptan, any other drugs, or any of the substances in almotriptan tablets, let your doctor and pharmacist know right once. Request a list of the components from your pharmacist.
  • If you have taken any of the following medications within the previous 24 hours, you should not take almotriptan: other selective serotonin receptor agonists like eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), or zolmitriptan (Zomig); or ergot- (Permax).
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, herbal items, and nutritional supplements you are now taking, have recently stopped taking, or intend to take. Mention any of the following: acetaminophen (Tylenol), aspirin, and nonsteroidal anti-inflammatory drugs (NSAIDS), such as ibuprofen (Advil, Motrin), naproxen (Aleve), and indinavir (Crixivan). nefazodone (Serzone); selective serotonin reuptake inhibitors (SSRIs) like fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax); Troleandomycin (TAO), zafirlukast, and selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), sibutramine (Meridia), and venlafaxine (Effexor) (Accolate). Tell your doctor or pharmacist if you take, or have recently discontinued taking, any of the following medications: erythromycin (E.E.S., E-Mycin, Erythrocin), itraconazole (Sporanox), ketoconazole (Nizoral), or ritonavir (Norvir). Additionally, let your physician or pharmacist know if you are currently taking any of the following drugs, or if you have just stopped taking them: monoamine oxidase (MAO) inhibitors, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your physician if you currently have or have ever had any of the following conditions: ischemic bowel disease, varicose veins, blood clots in the legs, Raynaud’s disease (problems with blood flow to the fingers, toes, ears, and nose), angina (chest pain), heart attack, irregular heartbeats, or angina. You can be advised by your doctor not to take almotriptan.
  • Inform your doctor if you smoke, are obese, have ever had high blood pressure, high cholesterol, diabetes, kidney disease, or liver disease; have recently experienced menopause (a change in your hormonal balance); or if any members of your family currently have, or have ever had, heart disease or a stroke.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. If you intend to engage in sexual activity while taking this medicine, discuss birth control options with your doctor. Call your doctor if you become pregnant while taking almotriptan.
  • You need to be aware that almotriptan might make you feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
  • To determine whether a migraine is to blame for your headaches, discuss them with your physician. Hemiplegic or basilar migraine, as well as headaches brought on by other disorders, should not be treated with almotriptan (such as cluster headaches).

What special dietary instructions should I follow?

If you plan to consume grapefruit juice while taking this medication, consult your doctor.

What side effects can this medication cause?

Almotriptan might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Uneasy stomach
  • Nausea
  • Drowsiness
  • Headache
  • Mouth ache
  • Dizziness

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
  • Hoarseness
  • Hives
  • Rash
  • Itching
  • Chest, throat, neck, or jaw tightness, pain, pressure, or weight
  • Slow or challenging speech
  • Faintness
  • Arm or leg weakness or numbness
  • Strong or sudden stomach discomfort
  • Bloody stools
  • Irregular, hammering, or quick heartbeat
  • Breathing difficulty
  • I started to get a cold sweat.
  • Breathing or swallowing challenges
  • Finger and toe colour being pale or blue
  • Having tingling, burning, or pain in your hands or feet

Other negative effects of almotriptan are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your doctor’s appointments. Regular blood pressure checks are advised.

Keep track of your headaches and when you take almotriptan by keeping a headache journal.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Axert®
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