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Avycaz (Generic Ceftazidime and Avibactam Injection)

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Why is this medication prescribed?

To treat abdominal (stomach area) infections, ceftazidime and avibactam injection is used with metronidazole (Flagyl). Additionally, it is used to treat renal and urinary tract infections as well as pneumonia that developed in patients who were hospitalised or on ventilators. Ceftazidime belongs to the group of drugs known as cephalosporin antibiotics. It eliminates bacteria to operate. The drug avibactam belongs to the group of drugs known as beta-lactamase inhibitors. It functions by stopping bacteria from metabolising ceftazidime.

Colds, the flu, and other viral infections cannot be treated with antibiotics like ceftazidime and avibactam. Antibiotic overuse increases the likelihood that you’ll develop an infection later on that is resistant to antibiotic treatment.

How should this medicine be used?

Ceftazidime with avibactam injection is available as a powder to mix with liquids and administer intravenously (into a vein). It is often intravenously administered (given slowly) over a period of two hours every eight hours. Your general health, the sort of infection you have, and how well you respond to therapy will all influence how long it takes. How long to use ceftazidime and avibactam injection is something your doctor will advise you on. Ceftazidime with avibactam injection can be administered at home or in a medical facility. Your doctor will instruct you on how to administer the ceftazidime and avibactam injection if you will be receiving it at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

During the first several days of treatment with ceftazidime and avibactam injection, you should start to feel better. Inform your doctor if your symptoms do not get better or worsen. After finishing the ceftazidime and avibactam injection, let your doctor know if you continue to experience signs of infection.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using ceftazidime and avibactam injection,

  • Inform your doctor and pharmacist if you have any allergies to ceftazidime and avibactam injection, carbapenem antibiotics like doripenem (Doribax), imipenem and cilastatin (Primaxin), or meropenem (Merrem); cephalosporin antibiotics like cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefdinir, cef Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention any of the following, if applicable: probenecid Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you have kidney disease now or ever have, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking ceftazidime and avibactam injection.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

There may be negative effects from using ceftazidime and avibactam injection. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Vomiting
  • Nausea
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Dizziness
  • Headache

Some adverse effects can be very harmful. Call your doctor right away if you experience any of these symptoms, or seek emergency care:

  • Trouble breathing or swallowing, hives, and a rash
  • Severe diarrhoea and faeces that are red or watery (up to 2 months after your treatment)
  • Seizures
  • Confusion
  • Sudden, uncontrollable twitching or jerking of your muscles
  • Hand trembling
  • Hearing voices or perceiving nonexistent objects
  • Coma (loss of consciousness for a period of time)

Other side effects could be brought on by avibactam injection and ceftazidime. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how your body is responding to the ceftazidime and avibactam injection, your doctor may request specific lab tests.

Ceftazidime and avibactam injection can skew the results of some urine glucose tests if you have diabetes. Discuss with your doctor which glucose tests you can use while receiving ceftazidime and avibactam injection treatment.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Avycaz®
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