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Avelox I.V. (Generic Moxifloxacin Injection)

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Having a tendon rupture (tearing of the fibrous tissue connecting a bone to a muscle) or tendinitis (swelling of the fibrous tissue that links a bone to a muscle) during therapy or for up to many months later increases the risk of using moxifloxacin injection. These issues could impact the tendons in your shoulder, hand, ankle’s back, or other portions of your body. Any age can get tendinitis or a ruptured tendon, although adults over 60 have the highest risk. Inform your physician if you have or have ever had kidney, heart, or lung illness; Rheumatoid arthritis, a condition in which the body attacks its own joints and results in pain, swelling, and loss of function, or if you engage in regular physical activity, are examples of joint or tendon disorders. If you are using oral or injectable steroids like dexamethasone, methylprednisolone (Medrol), or prednisone, let your doctor and pharmacist know (Rayos). Call your doctor right once, stop using moxifloxacin injection, and rest if you suffer any of the following tendinitis symptoms: A muscle may experience discomfort, edoema, soreness, rigidity, or trouble moving. Get immediate medical attention and discontinue using moxifloxacin injection if you suffer any of the following tendon rupture symptoms: hearing or feeling a snap or pop in a tendon area, bruising where a tendon area has been injured, or being unable to bear weight on the injured area are all signs of tendon injury.

Moxifloxacin injection use can result in nerve damage and sensory abnormalities that may persist even after you stop using the medication. As soon as you start using moxifloxacin injection, this injury could happen. If you have ever experienced peripheral neuropathy, let your doctor know (a type of nerve damage that causes tingling, numbness, and pain in the hands and feet). Call your doctor right away and stop using moxifloxacin injectable if you have any of the following signs: inability to feel light touch, vibrations, pain, heat, or cold; or numbness, tingling, discomfort, burning, or weakness in the arms or legs.

Use of moxifloxacin injections might cause sensory anomalies and nerve damage that may last long after you stop using the medication. This harm could occur as soon as you start using moxifloxacin injection. Inform your physician if you have ever developed peripheral neuropathy (a type of nerve damage that causes tingling, numbness, and pain in the hands and feet). If you have any of the following symptoms, call your doctor immediately and stop using moxifloxacin injectable: inability to feel light touch, vibrations, pain, heat, or cold; or numbness, tingling, discomfort, burning, or weakness in the arms or legs. lacking trust in people or believing that people are out to get you; hallucinations (hearing voices or seeing things that are not there); self-harming or suicide thoughts or actions; feeling uneasy, apprehensive, or melancholy; having memory loss or confusion; or displaying other changes in your mood or behaviour.

Myasthenia gravis is a nervous system ailment that causes significant muscle weakening. Using moxifloxacin injection may make this condition worse and perhaps result in death. If you have myasthenia gravis, tell your doctor. Your physician could advise against using moxifloxacin injectable. If your doctor prescribes moxifloxacin injection for your myasthenia gravis and you have muscle weakness or have trouble breathing while taking it, call your doctor right away.

Discuss the dangers of using moxifloxacin injection with your doctor.

When you start therapy with moxifloxacin injectable, your doctor or pharmacist will give you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the Food and Drug Administration (FDA) website ( or the manufacturer’s website.

Why is this medication prescribed?

Injections of moxifloxacin are used to treat skin infections, abdominal (stomach area) infections, and some bacterial infections like pneumonia. Injections of moxifloxacin are also used to prevent and cure plague, a deadly illness that can be intentionally disseminated as part of a bioterrorist strike. Although bronchitis and sinus infections can be treated with moxifloxacin injection, these disorders shouldn’t be treated with it if there are other accessible treatments. Fluoroquinolones are a class of antibiotics that includes moxifloxacin injectable. It functions by eradicating the infection-causing germs.

Colds, the flu, or other viral diseases cannot be treated with antibiotics such as moxifloxacin injection. Antibiotic overuse raises the likelihood that you’ll get an infection later on that is resistant to antibiotic therapy.

How should this medicine be used?

The moxifloxacin injection is a solution (liquid) that is administered via vein puncture using a needle or catheter. It is often intravenously (into a vein) administered over the course of at least 60 minutes, once every day for a period of five to twenty-one days. The type of infection being treated determines how long the treatment will last. How long to take moxifloxacin injectable is something your doctor will advise you on.

Both receiving and using moxifloxacin injection are options available to you. Your doctor will demonstrate how to administer the drug to you if you will be administering moxifloxacin injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional. If you experience any difficulties administering moxifloxacin injection, consult your healthcare practitioner for advice.

During the initial days of treatment with moxifloxacin injection, you should start to feel better. Call your doctor if your symptoms do not disappear or worsen.

Even if you feel better, continue taking the moxifloxacin injectable until the prescription is finished. Unless you encounter some of the major side effects indicated in the IMPORTANT WARNING and SIDE EFFECTS sections, do not discontinue taking moxifloxacin injectable without first consulting your doctor. Your illness could not be entirely treated if you stop using moxifloxacin injection too soon or if you miss doses, and the bacteria might develop an antibiotic resistance.

Other uses for this medicine

When other treatments are ineffective, moxifloxacin injection is also occasionally used to treat endocarditis (infection of the heart lining and valves), certain sexually transmitted illnesses, and tuberculosis (TB). If other medications are not available for this usage, moxifloxacin may also be used to treat or prevent anthrax (a dangerous infection that may be intentionally transmitted as part of a bioterror assault) in people who may have been exposed to anthrax bacteria in the air. Salmonella (an infection that causes severe diarrhoea) and shigella (an infection that causes severe diarrhoea) are other infections that can be treated with moxifloxacin injection in people who have HIV infection. The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using moxifloxacin injection,

  • If you are allergic to moxifloxacin, other quinolone or fluoroquinolone antibiotics like ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), or ofloxacin, any other medications, or any of the chemicals in moxifloxacin injection, let your doctor and pharmacist know right away. For a list of the ingredients, ask your doctor or pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention the drugs in the IMPORTANT WARNING section as well as any of the following: antidepressants, some antipsychotics, nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin, others), naproxen (Aleve, Naprosyn, others), cisapride (Propulsid) (not available in the U.S.), diuretics (‘water pills’), and some antidepressants; anticoagulants (‘blood thinners’) such as warfarin (Coumadin, Jantoven); erythromycin (E.E.S., Eryc, Erythrocin, among others); insulin or other drugs for diabetes management, such as chlorpropamide, glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta), tolazamide, and tolbutamide; and some drugs for irregular heartbeat, such as amiodarone (Nexterone, Pacerone), disopyr (Betapace, Betapace AF, Sorine, Sotylize). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you or anybody in your family currently has or has ever had a prolonged QT interval, let your doctor know (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death). Inform your doctor if you have or have ever had Marfan syndrome, high blood pressure, an aortic aneurysm (swelling of the big artery that transports blood from the heart to the body), an irregular or slow pulse, a heart attack, or any of these conditions (a genetic condition that can affect the heart, eyes, blood vessels and bones), If you have Ehlers-Danlos syndrome, a genetic disorder that can impact your skin, joints, or blood vessels, or if your blood potassium or magnesium levels are low. Additionally, let your doctor know if you now or ever had liver illness, diabetes, or low blood sugar issues.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you become pregnant while taking moxifloxacin injectable.
  • Until you are aware of how moxifloxacin injection affects you, avoid operating machinery, operating a vehicle, or engaging in other activities that call for attentiveness or coordination.
  • Plan to use protective clothes, sunglasses, and sunscreen and to avoid unnecessary or prolonged exposure to sunlight or UV radiation (tanning beds and sunlamps). Your skin may become photosensitive after receiving a moxifloxacin injection. If you get skin redness or blisters while receiving an injection of moxifloxacin, contact your doctor right once.

What special dietary instructions should I follow?

Throughout your moxifloxacin injectable treatment, be sure to regularly consume a lot of water or other liquids.

What should I do if I forget a dose?

The missed dose should be taken as soon as you remember. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from moxifloxacin injection are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Heartburn
  • At the injection site, there may be irritation, discomfort, tenderness, redness, warmth, or swelling

Stop using moxifloxacin injection and call your doctor right away, or seek emergency medical attention if you have any of the following symptoms, or any of the symptoms listed in the IMPORTANT WARNING section:

  • Severe diarrhoea (watery or bloody faeces), which may or may not be accompanied by fever and cramping in the stomach (may occur up to 2 months or more after your treatment)
  • Rash
  • Hives
  • Itching
  • Skin that is peeling or blistering
  • Fever
  • Swelling of the hands, feet, ankles, throat, eyes, cheeks, lips, tongue, and lower legs
  • Throat constriction or hoarseness
  • Breathing or swallowing challenges
  • Ongoing or getting worse cough
  • Skin or eye yellowing, paleness, dark urine, or light-colored stools
  • Extreme hunger or thirst, pale complexion, shaking, a racing or fluttering heartbeat, excessive sweating, frequent urination, trembling, blurred eyesight, or unusual anxiety
  • Loss of awareness or fainting
  • Abnormal bleeding or bruising
  • Unexpected discomfort in the back, stomach, or chest
  • Children who receive a moxifloxacin injection may experience complications with their bones, joints, and surrounding tissues. Children under the age of 18 should not receive a moxifloxacin injection.

Other negative effects of moxifloxacin injection are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Avelox® I.V.
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