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Avelox (Generic Moxifloxacin)

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During therapy or for up to several months afterward, taking moxifloxacin increases your risk of experiencing tendinitis (swelling of the fibrous tissue connecting a bone to a muscle) or a tendon rupture (tearing of the fibrous tissue connecting a bone to a muscle). These issues could impact the tendons in your shoulder, hand, ankle’s back, or other portions of your body. Any age can get tendinitis or a ruptured tendon, although adults over 60 have the highest risk. Inform your physician if you have or have ever had kidney, heart, or lung illness; Rheumatoid arthritis, a condition in which the body attacks its own joints and results in pain, swelling, and loss of function, or if you engage in regular physical activity, are examples of joint or tendon disorders. If you are using oral or injectable steroids like dexamethasone, methylprednisolone (Medrol), or prednisone, let your doctor and pharmacist know (Rayos). As soon as you notice any of the following tendinitis symptoms, stop taking moxifloxacin, get some rest, and contact your doctor right away: A muscle may experience discomfort, edoema, soreness, rigidity, or trouble moving. Stop taking moxifloxacin and seek emergency medical attention if you suffer any of the following tendon rupture symptoms: hearing or feeling a snap or pop in a tendon area; bruising following an injury to a tendon area; or being unable to move to or bear weight on the affected area.

When you use moxifloxacin, it may result in nerve damage and sensory abnormalities that may persist even after you stop using it. You might experience this damage quickly after starting to take moxifloxacin. If you have ever experienced peripheral neuropathy, let your doctor know (a type of nerve damage that causes tingling, numbness, and pain in the hands and feet). Call your doctor right away and stop taking moxifloxacin if you have any of the following symptoms: inability to feel light touch, vibrations, pain, heat, or cold; or numbness, tingling, discomfort, burning, or weakness in the arms or legs.

You may experience severe adverse effects from moxifloxacin use if it affects your neurological system or brain. Following the initial dose of moxifloxacin, this is possible. Inform your doctor if you currently have or previously had kidney illness, seizures, epilepsy, cerebral arteriosclerosis (narrowing of blood arteries in or around the brain that can cause a stroke or ministroke), stroke, or any other condition. Call your doctor right away and stop taking moxifloxacin if you have any of the following symptoms:seizures, tremors, lightheadedness, dizziness, headaches that won’t go away, trouble getting or keeping asleep, nightmares, a lack of confidence in people, or the impression that people are out to get you; Hallucinations (seeing or hearing objects or voices that are not there); suicidal thoughts or behaviours; memory issues; feelings of agitation, anxiety, nervousness, depression, or confusion; or other changes in your attitude or behaviour.

People who have myasthenia gravis, a neurological system illness that causes muscle weakness, may experience worsening muscle weakness after taking moxifloxacin, which could result in serious breathing problems or even death. If you have myasthenia gravis, tell your doctor. You can be advised by your doctor not to take moxifloxacin. If your doctor prescribes moxifloxacin for your myasthenia gravis and you have muscle weakness or have trouble breathing while taking the medication, call your doctor right away.

The dangers of using moxifloxacin should be discussed with your doctor.

When you start your moxifloxacin treatment, your doctor or pharmacist will provide you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. To access the Medication Guide, you can also check the manufacturer’s website or the Food and Drug Administration (FDA) website (

Why is this medication prescribed?

Moxifloxacin is used to treat several bacterial infections such pneumonia, skin, abdominal (stomach area), and abdominal infections. Additionally, plague—a deadly infection that may be intentionally spread as part of a bioterror attack—is prevented and treated using moxifloxacin. Although bronchitis and sinus infections can be treated with moxifloxacin, these disorders shouldn’t be treated with it if there are alternative accessible treatments. Moxifloxacin belongs to the fluoroquinolone family of antibiotics. It functions by eradicating the infection-causing germs.

Colds, the flu, or other viral diseases cannot be treated with antibiotics like moxifloxacin. Antibiotic overuse raises the likelihood that you’ll get an infection later on that is resistant to antibiotic therapy.

How should this medicine be used?

Moxifloxacin is available as an oral tablet. It is typically taken once day, with or without food, for 5 to 21 days. The type of infection being treated determines how long the treatment will last. How long to take moxifloxacin will be determined by your physician. Take moxifloxacin every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take moxifloxacin as prescribed by your doctor. Never take it in larger or less amounts or more frequently than directed by your doctor.

During the first several days of moxifloxacin therapy, you should start to feel better. Call your doctor if your symptoms do not disappear or worsen.

Even if you feel better, continue taking moxifloxacin until the prescription is finished. If you develop any of the serious adverse effects indicated in the IMPORTANT WARNING and SIDE EFFECTS sections, stop taking moxifloxacin immediately and consult your doctor. Your illness could not be entirely treated if you stop taking moxifloxacin too soon or if you skip doses, and the bacteria might develop an antibiotic resistance.

Other uses for this medicine

When other treatments are ineffective, moxifloxacin may also be used to treat endocarditis (infection of the heart lining and valves), some sexually transmitted illnesses, and tuberculosis (TB). If other medications are not available for this usage, moxifloxacin may also be used to treat or prevent anthrax (a dangerous infection that may be intentionally transmitted as part of a bioterror assault) in people who may have been exposed to anthrax bacteria in the air. Shigella and salmonella infections, both of which result in severe diarrhoea, are occasionally treated with moxifloxacin in individuals who simultaneously have an infection with the human immunodeficiency virus (HIV). The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking moxifloxacin,

  • If you are allergic to moxifloxacin, other quinolone or fluoroquinolone antibiotics like ciprofloxacin (Cipro), delafloxacin (Baxdela), gemifloxacin (Factive), levofloxacin (Levaquin), or ofloxacin; any other medications; or any of the ingredients in moxifloxacin tablets, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention the drugs in the IMPORTANT WARNING section as well as any of the following: Warfarin (Coumadin, Jantoven) and other anticoagulants (also known as “blood thinners”), as well as some antidepressants, antipsychotics (medications used to treat mental illness), nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin, etc.) and naproxen (Aleve, Naprosyn, etc.), cisapride (Propulsid); Several drugs for irregular heartbeats, such as amiodarone (Nexterone, Pacerone), disopyramide (Norpace), procainamide, quinidine (in Nuedexta), and sotalol; insulin or other medications to treat diabetes, such as chlorpropamide, glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta), tolazamide, and (Betapace, Betapace AF, Sorine, Sotylize). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Take moxifloxacin at least 4 hours before or at least 8 hours after taking any antacids that contain magnesium or aluminium (such as Maalox, Mylanta, or similar products), certain drugs like didanosine (Videx) solution, sucralfate (Carafate), or vitamin supplements that contain iron or zinc.
  • If you or anybody in your family currently has or has ever had a prolonged QT interval, let your doctor know (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death). Additionally, let your doctor know if you have or have ever experienced a slow or irregular heartbeat, a heart attack, an aortic aneurysm (swelling of the large artery that transports blood from the heart to the body), high blood pressure, peripheral vascular disease (poor blood circulation in the vessels), Marfan syndrome (a genetic condition that can affect the heart, eyes, blood vessels, and bones), Ehlers-Danlos syndrome (a genetic condition that can affect the skin or liver disease.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you become pregnant while taking moxifloxacin.
  • Until you are aware of how moxifloxacin affects you, avoid operating machinery, driving a car, or engaging in other tasks that call for attentiveness or coordination.
  • Plan to use protective clothes, sunglasses, and sunscreen and to avoid unnecessary or prolonged exposure to sunlight or UV radiation (tanning beds and sunlamps). Your skin could become photosensitive if you take roxifloxacin. If you get skin redness or blisters while taking moxifloxacin, contact your doctor right once.

What special dietary instructions should I follow?

Throughout your moxifloxacin therapy, be sure to regularly consume a lot of water or other liquids.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects with roxifloxacin are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Heartburn

Call your doctor right away or seek emergency medical assistance if you have any of the following symptoms while taking moxifloxacin, or any of the symptoms listed in the IMPORTANT WARNING section:

  • Severe diarrhoea (watery or bloody faeces), which may or may not be accompanied by fever and cramping in the stomach (may occur up to 2 months or more after your treatment)
  • Rash
  • Hives
  • Itching
  • Skin that is flaking or blistering
  • Fever
  • Swelling of the hands, feet, ankles, throat, eyes, cheeks, lips, tongue, and lower legs
  • Throat constriction or hoarseness
  • Breathing or swallowing challenges
  • Skin or eye yellowing, paleness, dark urine, or light-colored stools
  • Extreme hunger or thirst, pale complexion, shaking, a racing or fluttering heartbeat, excessive sweating, frequent urination, trembling, blurred eyesight, or unusual anxiety
  • Loss of awareness or fainting
  • Less urinations
  • Abnormal bleeding or bruising
  • Unexpected discomfort in the back, stomach, or chest

Children who take roxifloxacin may experience complications with their bones, joints, and tissues around their joints. Children under the age of 18 should not receive moxifloxacin.

Children who take roxifloxacin may experience complications with their bones, joints, and tissues around their joints. Children under the age of 18 should not receive moxifloxacin.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to moxifloxacin, your doctor could request specific lab tests. Your doctor might advise you to monitor your blood sugar more frequently if you have diabetes while using moxifloxacin.

No one else should take your medication. It’s likely that your prescription cannot be renewed. After you stop taking moxifloxacin, consult your doctor if you continue to experience infection-related symptoms.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Avelox®
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