Why is this medication prescribed?

Asacol (generic name: mesalamine) is primarily prescribed for the treatment of inflammatory bowel diseases such as ulcerative colitis and sometimes Crohn’s disease. It helps reduce inflammation in the colon and rectum, which can alleviate symptoms like diarrhea, abdominal pain, and rectal bleeding. Mesalamine works by acting topically on the lining of the intestines to suppress inflammation.

How should this medicine be used?

Asacol should be used according to your doctor’s instructions. Here are general guidelines for its use:

• Dosage: Take Asacol exactly as prescribed. The usual dosage is 400 mg or 800 mg tablets, depending on your condition and doctor’s recommendation. Typically, it’s taken 2 to 4 times a day.
• Administration: Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets as this can affect how the medication is released in the body.
• Consistency: Try to take the medication at the same times each day to help you remember.
• Food: It can be taken with or without food. However, if it upsets your stomach, taking it with food might help.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up to make up for a missed dose.
• Hydration: Drink plenty of fluids while on this medication, unless otherwise directed by your healthcare provider.
• Follow-up: Regular follow-up appointments with your healthcare provider may be necessary to monitor your condition and adjust the dosage if needed.

Always follow your healthcare provider’s specific instructions and consult them if you have any questions or experience side effects.

Other uses for this medicine

In addition to treating ulcerative colitis and Crohn’s disease, Asacol may also be used for:

• Proctitis: Inflammation of the rectum.
• Maintenance Therapy: To help maintain remission in ulcerative colitis or Crohn’s disease.

What special precautions should I follow?

Special Precautions for Asacol:

• Allergies: Inform your doctor if you are allergic to mesalamine or any other medications. Allergic reactions can include rash, itching, or swelling.
• Kidney Function: Mesalamine can affect kidney function. Your doctor may monitor your kidney function regularly, especially if you have a history of kidney problems.
• Liver Function: Regular liver function tests may be needed, particularly if you have a liver condition.
• Gastrointestinal Issues: If you have a history of gastrointestinal problems, such as ulcers or gastrointestinal bleeding, let your doctor know. Mesalamine can sometimes exacerbate these conditions.
• Interactions: Be cautious with other medications you are taking, including over-the-counter drugs and supplements. Inform your doctor about all medications you use to avoid potential interactions.
• Pregnancy and Breastfeeding: If you are pregnant, plan to become pregnant, or are breastfeeding, consult your doctor to weigh the benefits and risks of using Asacol.
• Symptoms of Inflammation: Monitor for symptoms such as severe abdominal pain, persistent diarrhea, or fever, and report them to your doctor promptly.
• Hydration: Ensure adequate hydration as mesalamine can affect fluid balance.

Always follow your healthcare provider’s advice and report any unusual symptoms or concerns while using Asacol.

What special dietary instructions should I follow?

• Hydration: Maintain adequate hydration by drinking plenty of fluids. This helps to prevent dehydration, especially if you experience gastrointestinal symptoms.
• Food Tolerance: Asacol can be taken with or without food. If you experience stomach upset, consider taking it with food to reduce discomfort.
• Dietary Adjustments: There are no specific dietary restrictions associated with Asacol, but maintaining a balanced diet and avoiding known triggers for your condition may help manage symptoms.

What should I do if I forget a dose?

• Take It ASAP: If you remember a missed dose shortly after the scheduled time, take it as soon as possible.
• Skip If Close to Next Dose: If it’s almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
• Consult Your Doctor: If you frequently miss doses or are unsure about what to do, consult your healthcare provider for advice.

What side effects can this medication cause?

Asacol (mesalamine) can cause various side effects. While many people tolerate the medication well, here are some potential side effects to be aware of:

Common Side Effects:

• Headache
• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Constipation
• Gas
• Rash

Less Common but Serious Side Effects:

• Kidney Issues: Symptoms like reduced urine output, swelling in the legs or feet, or weight gain could indicate kidney problems.
• Liver Issues: Symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or severe abdominal pain may signal liver problems.
• Severe Allergic Reactions: Symptoms like rash, itching, swelling, severe dizziness, or trouble breathing.
• Severe Gastrointestinal Issues: Persistent abdominal pain, severe diarrhea, or signs of gastrointestinal bleeding such as black or bloody stools.
• Pancreatitis: Symptoms include severe abdominal pain, nausea, vomiting, or fever.
• Blood Disorders: Symptoms like unusual bruising or bleeding, pale skin, or frequent infections could indicate blood-related issues.
• Lung Issues: Symptoms such as persistent cough, difficulty breathing, or chest pain.

If you experience any severe or persistent side effects, contact your healthcare provider immediately. Regular monitoring and communication with your doctor can help manage side effects effectively.

What should I know about storage and disposal of this medication?

Storage of Asacol:

• Store Asacol at room temperature, away from moisture and heat. Typically, this means keeping it in a dry place at a temperature between 68°F and 77°F (20°C to 25°C).
• Keep the medication in its original container with the lid tightly closed to protect it from moisture.
• Store it out of reach of children and pets to prevent accidental ingestion.

Disposal of Asacol:

• Do not flush Asacol down the toilet or pour it into a drain unless instructed to do so by specific disposal guidelines.
• Use a medication take-back program or a drug disposal kiosk if available in your area. Many pharmacies and community centers have programs for safe disposal of unused medications.
• If no take-back programs are available, mix the medication with an undesirable substance (like used coffee grounds or cat litter) and place it in a sealed plastic bag before throwing it away with your household trash.

In case of emergency/overdose

• Contact Emergency Services: If you suspect an overdose or experience severe symptoms, call emergency services or go to the nearest emergency room immediately.
• Symptoms of Overdose: Symptoms might include severe abdominal pain, persistent nausea or vomiting, or any other unusual symptoms.
• Information for Medical Personnel: Provide them with information about the amount of Asacol taken, the time of ingestion, and any other relevant details.

What other information should I know?

• Regular Monitoring: Regular follow-ups with your healthcare provider are important to monitor your response to the medication and any potential side effects.
• Medication List: Keep a current list of all medications you are taking and share it with your healthcare provider to avoid interactions and ensure effective treatment.
• Consultation: Always consult your healthcare provider before making any changes to your medication regimen or if you have concerns about your treatment.
• Emergency Contacts: Have emergency contact information readily available, including your doctor’s contact details and local poison control.

By following these guidelines, you can help ensure the effective and safe use of Asacol.