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Why is this medication prescribed?

Armodafinil is used to treat shift work sleep disorder and narcolepsy, two conditions that cause excessive daytime sleepiness (sleepiness during scheduled waking hours and difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts). In order to avoid the excessive sleepiness brought on by the obstructive sleep apnea/hypopnea syndrome, modafinil is also used in conjunction with breathing apparatuses or other treatments (OSAHS; a sleep disorder in which the patient briefly stops breathing or breathes shallowly many times during sleep and therefore does not get enough restful sleep). Armodafinil belongs to a group of drugs known as wakefulness-promoting agents. It functions by altering the concentrations of a few natural chemicals in the region of the brain that regulates sleep and wakefulness.

How should this medicine be used?

Armodafinil is available as an oral tablet. Typically, it is given once day. You will probably take armodafinil in the morning if you are using it to treat OSAHS or narcolepsy. You will most likely take armodafinil one hour before to the start of your shift if you are using it to treat shift work sleep disturbance. Take your daily dose of armodafinil about the same time. Without consulting your doctor, don’t alter the time of day you take your armodafinil. If your work shift doesn’t start at the same time every day, consult your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you do not understand, and carefully follow their instructions. Follow the medication’s directions precisely.

Armodafinil might lead to habit formation. Don’t take the medication in excess of what your doctor has suggested in terms of dosage, frequency, or duration.

Although armodafinil may make you feel less sleepy, it cannot treat your sleep issue. Even if you feel rested, keep taking armodafinil. Without consulting your doctor, do not discontinue taking armodafinil.

Using modafinil instead of obtaining enough sleep is not recommended. Obey your doctor’s recommendations for sound sleeping practises. If you have OSAHS, in particular, continue to utilise any breathing aids or other therapies that your doctor has advised.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking armodafinil,

  • If you have an allergy to modafinil (Provigil), armodafinil, or any other drugs, tell your doctor right away.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: Warfarin (Coumadin), clomipramine (Anafranil), cyclosporine (Gengraf, Neoral, Sandimmune), diazepam (Valium), erythromycin (E.E.S., E-Mycin, Erythrocin), and others are anticoagulants (also known as “blood thinners”). Midazolam; monoamine oxidase (MAO) inhibitors like isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); propranolol (Inderal); rifampin (Rifadin, Rimactane, in Rifamate); and triazolam. Keto (Halcion). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medications you are taking, even any not on this list, since many other drugs may also interact with armodafinil.
  • Inform your physician if you currently use or have previously used excessive amounts of street drugs, alcohol, or prescription medications. A heart attack, chest pain, high blood pressure, a mental illness like depression, mania (frenzied, abnormally excited mood), or psychosis (difficulty thinking clearly, communicating, understanding reality, and behaving appropriately), as well as heart, liver, or kidney disease should also be disclosed to your doctor.
  • Armodafinil may reduce the efficacy of hormonal contraceptives, so you should be aware of that (birth control pills, patches, rings, implants, injections, and intrauterine devices). While taking armodafinil and for a month after stopping, use another method of birth control. Discuss with your doctor the birth control methods that will be effective for you before, during, and after your armodafinil therapy.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking armodafinil.
  • Inform your doctor or dentist that you are taking armodafinil if you are having surgery, including dental surgery.
  • You should be aware that armodafinil may impair your decision-making, reasoning, and movement, and that it might not entirely alleviate the sleepiness brought on by your disorder. Prior to understanding how this drug affects you, avoid using machinery or driving a car. Even if you feel more alert, avoid driving and other risky activities if you avoided them due to your sleep disorder without first consulting your doctor.
  • Be warned that you should refrain from consuming alcohol while using this medication.

What special dietary instructions should I follow?

If you plan to consume grapefruits or grapefruit juice while taking this medication, consult your doctor.

What should I do if I forget a dose?

Ignore the missed dose and carry on with my normal dosing routine. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Armodafinil might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Dizziness
  • Having trouble falling or staying asleep
  • Having trouble focusing or paying attention
  • Body part shaking that is uncontrollable
  • Tingling, burning, or numbness in the hands or feet
  • Nausea
  • Vomiting
  • Heartburn
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Reduced appetite
  • Thirst
  • Mouth ache
  • Sweating
  • Often urinating

Some adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

  • Rash
  • Blisters
  • Skin shedding
  • Oral sores
  • Hives
  • Itching
  • Swelling of the lower legs, hands, arms, feet, ankles, lips, tongue, or eyes
  • Hoarseness
  • Breathing or swallowing challenges
  • Weakness
  • Chest pain
  • Erratic or pounding heartbeat
  • Agitated and unusually aroused mood
  • Hallucinating (seeing things or hearing sounds and voices that do not exist)
  • Anxiety
  • Depression
  • Consideration of suicide or self-harm

Other negative effects of modafinil are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Armodafinil should be kept in a secure location to prevent accidental or intentional consumption by others. Count the remaining tablets so you’ll know if any are missing.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

  • Agitation
  • Having trouble falling or staying asleep
  • Restlessness
  • Disorientation
  • Confusion
  • Hallucinating (seeing things or hearing sounds and voices that do not exist)
  • Nausea
  • Diarrhea
  • A quick or slow heartbeat
  • chest pain

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Armodafinil is illegal to sell or distribute. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Nuvigil®
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