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Aralen (Generic Chloroquine)

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Why is this medication prescribed?

Aralen (generic name: chloroquine) is primarily prescribed for malaria. Aralen is used to prevent and treat malaria caused by Plasmodium falciparum and Plasmodium vivax. It’s also used for treating other types of malaria. It can treat infections caused by Entamoeba histolytica, which can lead to severe diarrhea. Sometimes used off-label for autoimmune diseases like rheumatoid arthritis and lupus erythematosus due to its anti-inflammatory effects.

How should this medicine be used?

Here’s how it should be used:

  • Dosage: The dosage depends on the condition being treated and is typically prescribed by a healthcare provider. For malaria prevention, the dose might be taken weekly starting 1-2 weeks before travel to a malaria-endemic area and continuing for 4 weeks after leaving. For treatment, it might be given as a higher dose initially followed by a lower dose.
  • Administration: Aralen is usually taken orally in the form of tablets. It should be taken with food to reduce stomach upset.
  • Consistency: Follow the prescribed schedule exactly and complete the full course of treatment even if symptoms improve before finishing the medication.
  • Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose; do not double up to make up for a missed dose.
  • Storage: Store Aralen at room temperature, away from moisture and heat.

Always consult your healthcare provider for specific instructions tailored to your condition and treatment plan.

Other uses for this medicine

In addition to its primary uses, Aralen (chloroquine) has been investigated for other conditions, though these uses are less common:

  • Rheumatoid Arthritis: Used to reduce inflammation and pain.
  • Systemic Lupus Erythematosus (SLE): Helps manage symptoms and reduce flare-ups.
  • Porphyria Cutanea Tarda: Sometimes used to manage this condition affecting the skin.

What special precautions should I follow?

When using Aralen, consider the following precautions:

  • Allergies: Inform your healthcare provider if you have any allergies to chloroquine or similar medications.
  • Medical History: Share your complete medical history, especially if you have liver disease, vision problems, or have previously had a serious allergic reaction to chloroquine.
  • Vision Monitoring: Long-term use can lead to retinal damage. Regular eye exams are recommended.
  • Kidney and Liver Function: Chloroquine can affect liver and kidney function. Regular monitoring may be needed, especially if you have existing liver or kidney issues.
  • Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant or breastfeeding, as chloroquine can affect the fetus or infant.
  • Interactions: Inform your provider of all other medications, including over-the-counter drugs and supplements, as chloroquine can interact with other drugs.
  • Dosage Adjustments: Follow the prescribed dosage carefully. Overuse or misuse can lead to toxicity.
  • Alcohol: Limit alcohol intake, as it can increase the risk of side effects.
  • Side Effects: Watch for and report any unusual symptoms, such as vision changes, severe headache, or allergic reactions.

Always follow your healthcare provider’s instructions and consult them if you have concerns or questions about using Aralen.

What special dietary instructions should I follow?

  • Food Intake: Take Aralen with food to minimize stomach upset. Avoid taking it on an empty stomach unless instructed otherwise by your healthcare provider.
  • Alcohol: Limit or avoid alcohol, as it can increase the risk of side effects or affect the medication’s efficacy.

What should I do if I forget a dose?

  • Timing: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose; do not double up to make up for a missed dose.
  • Consultation: If you’re unsure about what to do or have missed multiple doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Aralen (chloroquine) can cause a range of side effects, some of which might be serious. Here’s a summary:

Common Side Effects:

  • Nausea: Feeling sick to your stomach.
  • Diarrhea: Loose or frequent bowel movements.
  • Headache: General pain in the head.
  • Dizziness: Feeling lightheaded or unsteady.
  • Loss of Appetite: Reduced desire to eat.
  • Skin Rash: Itching or rash on the skin.
  • Abdominal Pain: Discomfort or pain in the stomach area.
  • Hair Loss: Thinning or loss of hair.

Serious Side Effects:

  • Vision Changes: Blurred vision or changes in color vision, which could indicate retinal damage.
  • Hearing Loss: Ringing in the ears or hearing problems.
  • Severe Allergic Reactions: Swelling of the face, lips, or throat; severe itching or rash; trouble breathing.
  • Seizures: Convulsions or fits.
  • Severe Skin Reactions: Severe rash, peeling skin, or blistering.
  • Heart Issues: Irregular heartbeats or palpitations.
  • Liver Damage: Symptoms such as jaundice (yellowing of the skin or eyes), dark urine, or severe abdominal pain.
  • Mental Health Effects: Severe mood changes, confusion, or hallucinations.

If you experience any of these serious side effects or have concerns about how you’re feeling, contact your healthcare provider immediately. For less serious side effects, it’s still a good idea to discuss them with your doctor to ensure they’re managed appropriately.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aralen:

Storage:

  • Store Aralen at room temperature, typically between 68°F to 77°F (20°C to 25°C).
  • Keep it away from moisture and heat. Do not store in the bathroom or near a sink.
  • Keep the medication in its original container with the lid tightly closed.

Disposal:

  • Do not flush Aralen down the toilet or pour it into a drain unless instructed to do so by a disposal program.
  • Check if there are any local take-back programs or drug disposal kiosks in your area.
  • If no take-back programs are available, dispose of the medication in the household trash by mixing it with an undesirable substance (like used coffee grounds) and placing it in a sealed bag or container to prevent leakage.

In case of emergency/overdose

  • Immediate Action: Call emergency services or go to the nearest emergency room if you suspect an overdose.
  • Symptoms of Overdose: Symptoms may include severe headache, dizziness, seizures, confusion, visual disturbances, and abdominal pain.
  • Provide Information: When seeking medical help, provide information about the amount of Aralen taken and the time of ingestion if possible.

What other information should I know?

  • Regular Monitoring: If you are on long-term Aralen therapy, regular eye exams and liver function tests may be necessary.
  • Medical Follow-Up: Regular follow-ups with your healthcare provider are important to monitor for side effects and ensure the medication is working effectively.
  • Interactions: Be aware of potential drug interactions and inform your healthcare provider about all other medications and supplements you are taking.
  • Travel: If traveling to malaria-endemic areas, adhere strictly to the dosage and timing instructions for malaria prevention.

Always follow your healthcare provider’s specific instructions and contact them if you have any questions or concerns about Aralen.

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