WARNING

Aptensio XR (extended-release methylphenidate) is a medication commonly used to treat attention deficit hyperactivity disorder (ADHD). It is a stimulant that affects chemicals in the brain and nerves contributing to hyperactivity and impulse control. Here are some detailed risks and considerations associated with taking Aptensio XR:

• Increased Heart Rate and Blood Pressure: Stimulants like Aptensio XR can raise heart rate and blood pressure, which may be a concern for individuals with pre-existing cardiovascular conditions.
• Potential for Serious Heart Problems: In rare cases, stimulants can lead to severe cardiovascular events such as heart attack or stroke.
• Psychiatric Symptoms: Some individuals may experience worsening of existing psychiatric disorders or new symptoms like hallucinations, delusions, or paranoia.
• Mood Changes: Anxiety, agitation, or mood swings may occur.
• Risk of Abuse: Methylphenidate is a controlled substance due to its potential for abuse and dependence. Misuse can lead to addiction.
• Tolerance Development: Over time, some individuals may develop tolerance, requiring higher doses for the same effect.
• Impact on Growth: Long-term use of stimulants in children can lead to a reduction in growth rate. Regular monitoring is advised.
• Seizures: There is a potential risk of seizures, particularly in individuals with a history of seizures or other neurological conditions.
• Appetite Suppression: Aptensio XR can lead to reduced appetite, which might result in weight loss or nutritional deficiencies.
• Abdominal Pain: Some individuals may experience stomach pain or discomfort.
• Insomnia: Difficulty sleeping is a common side effect, which can affect overall health and quality of life.
• Dizziness: Some users may feel lightheaded or dizzy.
• Headaches: Headaches can occur as a side effect of the medication.
• Pre-existing Conditions: Individuals with a history of cardiovascular disease, mental health disorders, or substance abuse should use Aptensio XR with caution.
• Interactions with Other Medications: Aptensio XR can interact with other medications, including certain antidepressants and blood pressure medications.
• Regular Check-ups: Regular follow-ups with a healthcare provider are important to monitor for adverse effects and effectiveness.
• Dosage Adjustments: The dose may need to be adjusted based on response and side effects.

Always consult with a healthcare professional before starting or adjusting any medication. They can provide personalized advice and monitor for potential side effects based on individual health conditions and needs.

Why is this medication prescribed?

Aptensio XR is prescribed primarily for the treatment of attention deficit hyperactivity disorder (ADHD). It helps manage symptoms of ADHD, such as:

• Inattention: Difficulty focusing on tasks and sustaining attention.
• Hyperactivity: Excessive restlessness and an inability to stay still.
• Impulsivity: Acting without thinking and difficulty controlling impulses.

By increasing the levels of certain neurotransmitters in the brain, Aptensio XR helps improve concentration, reduce impulsivity, and enhance overall behavioral control in individuals with ADHD.

How should this medicine be used?

Aptensio XR (methylphenidate extended-release) is used to treat attention deficit hyperactivity disorder (ADHD). Here are some general guidelines for its use:

• Dosage: Follow your healthcare provider’s instructions for the dosage. Typically, Aptensio XR is taken once daily in the morning. The dosage can be adjusted based on your response and tolerability.
• Administration: Take Aptensio XR with or without food. Swallow the capsule whole; do not chew or crush it. If you have difficulty swallowing capsules, consult your healthcare provider for alternative options.
• Consistency: Try to take it at the same time each day to help with routine and effectiveness.
• Missed Dose: If you miss a dose, skip it and take your next dose at the regular time. Do not take two doses at once to make up for a missed dose.
• Alcohol and Drug Interactions: Avoid alcohol and inform your healthcare provider about all other medications or supplements you are taking, as there may be interactions.
• Storage: Store Aptensio XR at room temperature, away from moisture and heat.

Always follow your healthcare provider’s specific instructions for your treatment plan and consult them if you have any questions or concerns about using Aptensio XR.

Other uses for this medicine

Aptensio XR is primarily used for managing ADHD. However, its use outside of ADHD is not commonly established or approved. Off-label uses are possible but should be discussed with a healthcare provider.

What special precautions should I follow?

Special Precautions for Aptensio XR:

• Cardiovascular Conditions: If you have a history of heart disease, high blood pressure, or other cardiovascular conditions, your healthcare provider should monitor you closely for potential effects on heart rate and blood pressure.
• Mental Health: Be aware of any changes in mood, new psychiatric symptoms, or worsening of existing mental health conditions. Report any unusual symptoms to your healthcare provider.
• Substance Abuse: Aptensio XR is a controlled substance due to its potential for abuse. Use it only as prescribed and keep it out of reach of others.
• Growth Monitoring: Regularly monitor growth in children taking Aptensio XR, as long-term use can impact growth rate.
• Seizure History: If you have a history of seizures or neurological conditions, discuss the risks with your healthcare provider, as stimulants can increase the risk of seizures.
• Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential drug interactions, including antidepressants and blood pressure medications.
• Pregnancy and Breastfeeding: If you are pregnant or planning to become pregnant, or if you are breastfeeding, discuss the potential risks and benefits with your healthcare provider.
• Missed Dose Management: Do not take a double dose if you miss one. Follow your provider’s instructions for managing missed doses.

Following these precautions and maintaining open communication with your healthcare provider can help manage the risks associated with Aptensio XR and ensure its effective and safe use.

What special dietary instructions should I follow?

Aptensio XR does not require specific dietary instructions. However, maintaining a balanced diet can help manage any potential appetite suppression and ensure overall health.

What should I do if I forget a dose?

• Take as Soon as Possible: If you remember within a few hours of the missed dose, take it as soon as you can.
• Avoid Double Dosing: If it’s almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once to make up for a missed dose.
• Seek Guidance: If you are unsure about what to do or have missed multiple doses, consult your healthcare provider for advice.

What side effects can this medication cause?

Aptensio XR can cause a range of side effects, which can vary in severity. Common side effects include:

Common Side Effects:

• Appetite Loss: Decreased appetite leading to potential weight loss.
• Insomnia: Difficulty sleeping or disrupted sleep patterns.
• Headache: Pain or discomfort in the head.
• Stomach Pain: Abdominal discomfort or pain.
• Nausea: Feeling of queasiness or the urge to vomit.
• Dry Mouth: Reduced saliva production leading to a dry mouth.
• Dizziness: Feeling lightheaded or unsteady.

Less Common but Serious Side Effects:

• Cardiovascular Issues: Increased heart rate, elevated blood pressure, and, in rare cases, serious events such as heart attack or stroke.
• Psychiatric Symptoms: New or worsening symptoms such as anxiety, agitation, mood swings, hallucinations, or delusions.
• Seizures: Risk of seizures, especially in individuals with a history of neurological conditions.
• Growth Suppression: Potential reduction in growth rate in children with long-term use.
• Allergic Reactions: Symptoms such as rash, itching, swelling, or trouble breathing.
• Report Side Effects: Contact your healthcare provider if you experience any severe or concerning side effects.
• Seek Immediate Help: For serious reactions like chest pain, severe allergic reactions, or signs of a stroke (e.g., sudden weakness, confusion, difficulty speaking), seek emergency medical attention immediately.

Regular monitoring by a healthcare provider can help manage side effects and ensure the medication is used safely and effectively.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aptensio XR:

• Storage:
  • Store Aptensio XR at room temperature, typically between 68°F to 77°F (20°C to 25°C).
  • Keep it away from moisture, heat, and direct sunlight.
  • Store the medication in a secure place, out of reach of children and pets.
• Disposal:
  • If you need to dispose of unused or expired medication, use a drug take-back program or a pharmacy return program if available.
  • Follow specific disposal instructions provided by your pharmacist or healthcare provider.
  • Avoid flushing the medication down the toilet or pouring it into drains unless specifically instructed to do so.

In case of emergency/overdose

• Severe Symptoms: Symptoms of an overdose may include agitation, hallucinations, tremors, muscle twitching, rapid heartbeat, fever, nausea, vomiting, or seizures.
• Severe Reactions: In extreme cases, it can lead to severe cardiovascular problems or other life-threatening conditions.
• Contact Emergency Services: Call emergency medical services (911) or go to the nearest emergency room immediately.
• Inform Medical Personnel: Provide them with information about the medication, dosage, and timing of ingestion.

What other information should I know?

• Regular Check-Ups: Regular appointments with your healthcare provider are important to assess the effectiveness of the medication and make any necessary adjustments.
• Interactions: Inform your healthcare provider about all other medications, including over-the-counter drugs and supplements, to avoid potential interactions.
• Personal Health Information: Update your healthcare provider on any changes in your health status or new symptoms that arise.
• Adherence: Take Aptensio XR exactly as prescribed to maximize benefits and minimize risks.

If you have any specific concerns or questions about Aptensio XR, your healthcare provider can offer guidance tailored to your individual situation.