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Apresazide (Generic Hydralazine)

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Why is this medication prescribed?

High blood pressure is treated with hydralazine. The drug hydralazine belongs to the vasodilators class of drugs. In order to facilitate easier blood flow throughout the body, it acts by relaxing the blood vessels.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

Hydralazine is available as an oral tablet. Usually, two to four doses per day are given. Hydralazine should be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Use hydralazine as prescribed by your doctor. Never take it in larger or less amounts or more frequently than directed by your doctor.

Although it doesn’t treat high blood pressure, hydralazine manages it. Even if you feel good, keep taking the hydralazine medication. Without consulting your doctor, do not discontinue taking hydralazine.

Other uses for this medicine

Additionally, hydralazine is used to treat heart failure and following heart valve replacement. Discuss the potential dangers of using this medication for your illness with your doctor.

Ask your doctor or pharmacist for more details if you’re interested in using this medication for any other conditions.

What special precautions should I follow?

Before taking hydralazine,

  • If you have an allergy to hydralazine, aspirin, tartrazine (a yellow food colouring used in some processed foods and drugs), any other medications, or any of the components in hydralazine tablets, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, and dietary supplements you are currently taking or intend to take. Mention indomethacin (Indocin, Tivorbex), metoprolol (Lopressor, Toprol-XL, in Dutoprol), and propranolol if you have any of these (Inderal LA, Innopran XL, in Inderide).
  • Inform your doctor if you have ever experienced a heart attack, have coronary artery disease, rheumatic heart disease, heart, kidney, or liver illness, or if you have any of these conditions.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking hydralazine.
  • Inform your doctor or dentist that you are taking hydralazine if you are getting surgery, including dental surgery.
  • Consult your doctor about drinking responsibly while taking hydralazine. The negative effects of hydralazine can be exacerbated by alcohol.

What special dietary instructions should I follow?

With meals or as a snack, take hydralazine.

Your doctor might advise a low-sodium or low-salt diet. Pay close attention to these guidelines.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from hydralazine are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Flushing
  • Headache
  • Uneasy stomach
  • Vomiting
  • Reduced appetite
  • Diarrhea
  • Constipation
  • Teary eyes
  • Clogged nose
  • Rash

Some adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms:

  • Fainting
  • Muscle or joint pain
  • Rapid heartbeat
  • Fever
  • Chest pain
  • Swollen feet or ankles
  • Tingling or numbness in the feet or hands

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

All medications should be kept out of the sight and reach of children, as many of the containers (such as weekly pill containers and those for eye drops, lotions, patches, and inhalers) are not child-resistant and are simple for small children to open. Always lock safety caps and put the medication in a secure spot right away, up high and out of young children’s sight and reach, to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. You should routinely monitor your blood pressure to see how hydralazine affects you.

You might be required to monitor your blood pressure everyday by your doctor. To learn how, ask your doctor or pharmacist.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Apresoline®
  • Dralzine®
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