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APAP (Generic Acetaminophen Injection)

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Why is this medication prescribed?

Injections of acetaminophen are used to treat mild to moderate pain and to lower temperature. To treat moderate to severe pain, acetaminophen injection is sometimes used with opioid (narcotic) drugs. A class of drugs known as analgesics (pain relievers) and antipyretics includes acetaminophen (fever reducers). It functions by altering how the body perceives pain and by cooling the body.

How should this medicine be used?

Acetaminophen injection is available as a liquid solution that is injected into a vein over a 15-minute period. To ease pain or lower temperature, it is often administered every 4 to 6 hours as needed.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving acetaminophen injection,

  • If you have an allergy to acetaminophen, any other drugs, or any of the ingredients in acetaminophen injection, let your doctor and pharmacist know right away. For a list of ingredients, speak with your pharmacist or physician.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are currently taking or intend to use. Make careful to specify “blood thinners” or anticoagulants such warfarin (Coumadin), disulfiram (Antabuse), and isoniazid (INH, Nydrazid, in Rifamate, in Rifater). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. To ensure that you don’t take too much acetaminophen, let your doctor know if you’re taking any other products that contain it (such as Tylenol, which is a common ingredient in over-the-counter and prescription drugs for fever, pain, and cold and flu symptoms).
  • If you have liver illness now or ever had it, let your doctor know. Most likely, your doctor will advise against using acetaminophen injection.
  • If you consume excessive amounts of alcohol, have experienced severe vomiting or diarrhoea, suspect you may be dehydrated, are unable to consume enough food and liquids to maintain your health, or have ever had renal illness, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking an acetaminophen injection.
  • Inquire with your doctor or pharmacist about whether drinking alcohol is safe while receiving an injection of acetaminophen.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

Side effects from acetaminophen injection are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Constipation
  • Headache
  • Agitation
  • Having trouble falling and staying asleep
  • Pain where the injection site for the medicine was

Some adverse effects can be very harmful. Call your doctor right away if any of these symptoms occur to you:

  • Rash
  • Hives
  • Itching
  • Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
  • Hoarseness
  • Breathing or swallowing challenges

Other negative effects of acetaminophen injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

You’ll most likely receive your acetaminophen injection in a medical setting that keeps it on hand. If you have any concerns about how to store your medication, consult your doctor.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Even if there are no symptoms, get medical attention right once if someone has received an excessive dose of acetaminophen injection. Overdose signs could include the following:

  • Nausea
  • Sweating
  • Appetite loss
  • Extreme fatigue
  • Not enough energy
  • Uncommon bruising or bleeding
  • Upper right stomach region discomfort
  • The skin or eyes turning yellow
  • Flu-like signs
  • Urine with a deep colour
  • Coma (loss of consciousness)

What other information should I know?

Inform the lab staff and your doctor that you are receiving an acetaminophen injection prior to any laboratory test.

Any queries you may have regarding acetaminophen injection, ask your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Ofirmev®
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