WARNING

Angeliq, which combines estrogen and progestin, is used for hormone replacement therapy (HRT) to manage menopausal symptoms. Here are some key risks associated with its use:

• Cardiovascular Issues: Increased risk of blood clots, stroke, and heart attack.
• Breast Cancer: Potentially increases the risk of developing breast cancer.
• Endometrial Cancer: If used without progestin, it may increase the risk of endometrial cancer.
• Liver Problems: Can cause liver dysfunction or liver disease.
• Gallbladder Disease: Increased risk of gallbladder disease and gallstones.
• Mood Changes: May cause mood swings, depression, or anxiety.
• Migraines: Can trigger or worsen migraines.
• Weight Gain: Possible weight gain or fluid retention.

It’s important to discuss these risks with your healthcare provider to determine if Angeliq is appropriate for your needs.

Why is this medication prescribed?

Angeliq, which combines estrogen and progestin, is commonly prescribed for hormone replacement therapy (HRT). It is used to manage symptoms associated with menopause, such as hot flashes, vaginal dryness, and mood changes. Additionally, it can help prevent bone loss (osteoporosis) that can occur after menopause. The combination of estrogen and progestin helps balance hormones and reduces the risk of uterine cancer that can be associated with estrogen-only therapy.

How should this medicine be used?

Angeliq should be used according to your healthcare provider’s instructions. Here’s a general guide on how it is typically used:

• Dosage: Angeliq usually comes in tablet form, and the typical dose is one tablet taken once daily. The exact dosage and schedule may vary based on individual needs and the specific formulation prescribed.
• Administration: Take Angeliq at the same time each day to help remember your dose. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
• Duration: The duration of treatment depends on your symptoms and your healthcare provider’s recommendations. HRT is often used for a limited time to manage menopause symptoms, but the duration should be reassessed periodically with your provider.
• Missed Dose: Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses to make up for a missed dose.
• Regular Check-Ups: Schedule regular appointments with your healthcare provider to monitor your health, assess the effectiveness of the therapy, and check for any potential side effects.
• Storage: Keep Angeliq in its original container to protect it from light and moisture. Store at room temperature (typically between 68°F to 77°F or 20°C to 25°C).
• Disposal: Follow your local guidelines for the disposal of medications. Do not flush tablets down the toilet or throw them in the trash without proper disposal procedures.

Always follow your healthcare provider’s specific instructions for use and consult them if you have any questions or concerns about how to take Angeliq.

Other uses for this medicine

Besides managing menopause symptoms, Angeliq may be used for:

• Preventing Osteoporosis: It can help reduce the risk of bone loss (osteoporosis) in postmenopausal women.
• Management of Severe Menstrual Disorders: It might be used in certain cases of severe menstrual disorders or abnormal uterine bleeding in premenopausal women.

What special precautions should I follow?

Special Precautions for Angeliq:

• Cardiovascular Health: Inform your healthcare provider if you have a history of heart disease, stroke, or blood clots.
• Cancer History: Notify your provider if you have a history of breast, uterine, or ovarian cancer.
• Liver Disease: If you have liver disease or liver problems, your provider will need to monitor your liver function.
• Regular Mammograms: Regular breast exams and mammograms are important to monitor for any signs of breast cancer.
• Pelvic Exams: Regular pelvic exams are recommended to monitor for any abnormalities.
• Blood Clot Risk: If you are at risk for blood clots, your healthcare provider might recommend more frequent monitoring or alternative treatments.
• Smoking: Smoking can increase the risk of cardiovascular issues and blood clots with HRT. If you smoke, discuss this with your provider.
• Drug Interactions: Inform your provider about all other medications, supplements, or herbal products you are taking to avoid potential interactions.
• Not for Use During Pregnancy: Angeliq is not recommended for use during pregnancy. If you become pregnant while taking Angeliq, contact your healthcare provider immediately.
• Report Unusual Symptoms: Report any unusual symptoms, such as severe headaches, vision changes, leg swelling, or chest pain, to your provider promptly.
• Monitor Mood Changes: If you experience significant mood changes or symptoms of depression, inform your healthcare provider.

Always follow the specific guidance provided by your healthcare provider and consult them with any concerns or questions about Angeliq. Regular monitoring and communication with your provider are essential for safe and effective use.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Angeliq. However, maintaining a healthy diet and regular exercise can support overall well-being and might help mitigate some side effects of HRT.

What should I do if I forget a dose?

• Take as Soon as Possible: If you remember within a few hours of your missed dose, take it as soon as you remember.
• Skip if Close to Next Dose: If it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed dose.
• Consult Your Provider: If you miss doses frequently or have questions about missed doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Angeliq, like other hormone replacement therapies, can cause a range of side effects. Here are some common and less common side effects associated with Angeliq:

Common Side Effects:

• Headaches: Some users may experience headaches or migraines.
• Nausea: Feeling nauseous is a common side effect.
• Breast Tenderness: You might experience sore or tender breasts.
• Mood Changes: Mood swings or changes in emotional state can occur.
• Weight Gain: Weight gain or changes in appetite might be observed.
• Spotting or Bleeding: Irregular spotting or bleeding between periods may occur, especially during the first few months of treatment.

Less Common or Serious Side Effects:

• Blood Clots: Risk of developing blood clots in veins (deep vein thrombosis) or lungs (pulmonary embolism).
• Heart Attack or Stroke: Increased risk of cardiovascular events, such as heart attack or stroke.
• Breast Cancer: Potential increased risk of developing breast cancer with long-term use.
• Uterine Cancer: Higher risk of endometrial (uterine) cancer if not using progestin along with estrogen.
• Gallbladder Disease: Risk of developing gallstones or gallbladder disease.
• Liver Problems: Potential for liver function issues or liver disease.
• Vision Changes: Rarely, changes in vision may occur.
• Severe Allergic Reactions: Signs include rash, itching, swelling, severe dizziness, or trouble breathing.

Some side effects may resolve on their own after a few weeks of treatment. If you experience mild side effects, monitor them and discuss them with your healthcare provider at your next appointment. If you experience severe symptoms or any of the serious side effects mentioned, contact your healthcare provider immediately. Seek emergency medical attention for symptoms like chest pain, sudden shortness of breath, or severe headaches.

Regular check-ups with your healthcare provider are important to monitor for side effects and adjust treatment if necessary. Always report any new or unusual symptoms to your provider.

What should I know about storage and disposal of this medication?

Storage and Disposal of Angeliq:

• Storage:
  • Store Angeliq at room temperature, typically between 68°F to 77°F (20°C to 25°C).
  • Keep the medication in its original container, tightly closed, and protected from light and moisture.
  • Store Angeliq out of reach of children and pets.
• Disposal:
  • Do not flush Angeliq down the toilet or pour it into a drain unless instructed to do so by your pharmacist.
  • Use drug take-back programs or community disposal sites if available. These programs are often the safest way to dispose of unused medications.
  • If no take-back programs are available, mix Angeliq with an undesirable substance like used coffee grounds or cat litter, place it in a sealed plastic bag, and dispose of it in the household trash. Be sure to remove any personal information from the prescription label before disposal.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms of an overdose might include nausea, vomiting, and unusual bleeding. Seek immediate medical attention if you suspect an overdose.
• Contact Emergency Services: Call emergency services (911) or go to the nearest emergency room.
• Inform Healthcare Providers: Provide healthcare professionals with information about the amount of Angeliq taken and the time of ingestion.

What other information should I know?

• Regular Monitoring: Regular check-ups with your healthcare provider are important to monitor the effectiveness of Angeliq and to detect any potential side effects early.
• Health Changes: Inform your healthcare provider of any significant health changes, new medications, or symptoms that arise during treatment.
• Interactions: Be aware of potential interactions with other medications or supplements you may be taking. Always consult your healthcare provider before starting new treatments.
• Lifestyle Factors: Maintain a healthy lifestyle, including a balanced diet and regular exercise, to support overall well-being while on Angeliq.
• Consistency: Take Angeliq exactly as prescribed and do not adjust the dose or frequency without consulting your healthcare provider.

Always follow the specific instructions given by your healthcare provider and consult them with any questions or concerns regarding Angeliq.