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Amrix (Generic Cyclobenzaprine)

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Why is this medication prescribed?

To relax muscles and ease pain and discomfort brought on by sprains, strains, and other muscle injuries, cyclobenzaprine is administered along with rest, physical therapy, and other methods. The drug cyclobenzaprine belongs to the group of drugs known as skeletal muscle relaxants. It functions by having an effect on the nerve system and brain, enabling the muscles to relax.

How should this medicine be used?

The oral forms of cyclobenzaprine are a tablet and an extended-release capsule. The tablet is often taken three times day, with or without food. The extended-release capsule is typically taken once per day with or without food. Without consulting your doctor, do not take this medication for longer than three weeks. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Exactly as prescribed, use cyclobenzaprine. Never take it in larger or less amounts or more frequently than directed by your doctor.

Do not chew or shatter the extended-release capsules; instead, swallow them whole.

Mix the extended-release capsule’s contents with applesauce if you are unable to take it whole. Immediately consume the concoction and swallow it without chewing. After eating the mixture, sip some liquid, swish it about in your mouth, then swallow it to ensure that you’ve ingested all the medication.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

What special precautions should I follow?

Before taking cyclobenzaprine,

  • If you have an allergy to cyclobenzaprine, any other medications, or any of the substances in cyclobenzaprine tablets or capsules, tell your doctor and pharmacist very away. Request a list of the components from your pharmacist.
  • Monoamine oxidase (MAO) inhibitors, such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine, should be mentioned to your doctor if you are currently taking any of these drugs or have stopped taking them within the previous two weeks (Parnate). If you take one of these drugs, your doctor will probably advise you not to take cyclobenzaprine.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter medications, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: Meperidine (Demerol), barbiturates such butabarbital (Butisol), phenobarbital, and secobarbital (Seconal), sedatives, sleeping pills; bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban); allergy, cough, and cold drugs; SSRIs, or selective serotonin reuptake inhibitors, include fluoxetine (Prozac, Sarafem, Selfemra, and in Symbyax), citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), and paroxetine (Brisdelle, Paxil, Pexeva), venlafaxine (Effexor), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), and sertraline (Zoloft); selective serotonin and norepinephrine reuptake inhibitors (SNRIs); tranquilizers, tricyclic antidepressants (TCAs), such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil), tramadol (Conzip Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all the medications you are taking, even those not on this list, since many other drugs may also interact with cyclobenzaprine.
  • If you have an overactive thyroid gland or are recovering from a recent heart attack, let your doctor know. heart failure, an irregular heartbeat, a heart block, or any other issues with your heart’s electrical impulses. Heart failure is a condition when the heart cannot pump enough blood to the other areas of the body. Most likely, your doctor will advise against taking cyclobenzaprine.
  • If you have glaucoma, high eye pressure, trouble peeing, or liver illness, let your doctor know.
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor right away if you find out you’re pregnant while taking cyclobenzaprine.
  • If you are 65 years of age or older, discuss the advantages and disadvantages of taking cyclobenzaprine with your doctor. Since cyclobenzaprine is less safe and less successful than alternative drugs that can be used to treat the same condition, older persons should often avoid taking it.
  • You should be aware that this medication might make you sleepy. Until you are certain of how cyclobenzaprine may effect you, do not operate machinery or drive a car.
  • Consult your doctor about whether drinking alcohol is safe while taking cyclobenzaprine. Alcohol’s negative effects may be exacerbated by cyclobenzaprine.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Side effects from cyclobenzaprine are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Mouth ache
  • Dizziness
  • Nausea
  • Constipation
  • Heartburn

Call your doctor right away if you have any of the following symptoms:

  • Skin rash
  • Hives
  • Facial or tongue swelling
  • Breathing or swallowing challenges
  • Rapid or irregular heartbeat
  • Chest pain

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom). Away from light, keep the extended-release capsule.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose signs could include the following:

  • Drowsiness
  • Rapid or erratic heartbeat
  • Feeling agitated
  • Confusion
  • Difficulty moving or speaking
  • Dizziness
  • Nausea
  • Vomiting
  • Hallucination (seeing things or hearing sounds and voices that do not exist)
  • Tremor
  • Consciousness loss

What other information should I know?

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Amrix®
  • Flexeril®
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