Why is this medication prescribed?

Ampyra (generic dalfampridine) is prescribed to improve walking ability in patients with multiple sclerosis (MS). It helps by enhancing the conduction of nerve impulses, which can lead to improved motor function and mobility in individuals with MS who have difficulty walking. This medication does not cure MS but can help manage some of the symptoms associated with the disease.

How should this medicine be used?

How to use Ampyra:

• Dosage: The typical dose is 10 mg taken twice a day, approximately 12 hours apart. It’s important to follow the dosing schedule exactly as prescribed by your healthcare provider.
• Administration: Take the medication orally with or without food. Swallow the tablets whole; do not crush, chew, or split them.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose; do not take two doses at once to make up for a missed dose.
• Storage: Store Ampyra at room temperature, away from moisture and heat.
• Precautions: Inform your doctor about any other medications you’re taking and any medical conditions you have, particularly kidney issues, as dosing adjustments may be needed. Regular monitoring by your healthcare provider may be necessary to ensure the medication is working effectively and to check for any potential side effects.

If you have any concerns or experience side effects, be sure to discuss them with your healthcare provider.

Other uses for this medicine

Other Uses for Ampyra:

• Primary Use: As mentioned, Ampyra is primarily used to improve walking in patients with multiple sclerosis (MS).
• Off-Label Uses: There are no widely recognized off-label uses for Ampyra. Its use outside of improving walking in MS patients is not well-established or supported by strong evidence.

What special precautions should I follow?

Special Precautions for Ampyra:

• Kidney Function: Ampyra is excreted through the kidneys, so if you have kidney problems, your doctor may need to adjust your dose or monitor your kidney function closely.
• Seizure History: This medication can increase the risk of seizures, especially if you have a history of seizures or certain other conditions that might predispose you to seizures.
• Other Medications: Inform your healthcare provider about all the medications you’re taking, including over-the-counter drugs and supplements, as some may interact with Ampyra.
• Allergies: Let your doctor know if you have any known allergies to dalfampridine or other ingredients in the medication.
• Pregnancy and Breastfeeding: The safety of Ampyra during pregnancy or breastfeeding has not been well established. Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Regular Monitoring: Regular follow-ups with your healthcare provider may be necessary to monitor your response to the medication and check for any side effects.

Always follow your healthcare provider’s instructions and consult them with any concerns or symptoms.

What special dietary instructions should I follow?

There are no specific dietary restrictions or instructions associated with Ampyra. However, maintaining a balanced diet and staying hydrated can contribute to overall health and potentially help with the medication’s effectiveness.

What should I do if I forget a dose?

• Timing: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose; do not take two doses at once to make up for the missed one.
• Routine: Try to take your medication at the same times each day to help keep track and minimize missed doses.

What side effects can this medication cause?

Ampyra (dalfampridine) can cause various side effects. Some of the more common and serious side effects include:

Common Side Effects:

• Dizziness: Some people may feel dizzy when taking Ampyra.
• Headache: Headaches can occur as a side effect.
• Nausea: Feeling nauseated or experiencing upset stomach is possible.
• Insomnia: Difficulty sleeping may be reported.

Serious Side Effects:

• Seizures: Ampyra can increase the risk of seizures, particularly in individuals with a history of seizures or certain risk factors.
• Kidney Issues: Problems with kidney function can occur, particularly in those with pre-existing kidney conditions.
• Severe Allergic Reactions: Symptoms of a severe allergic reaction can include rash, itching, swelling, severe dizziness, or trouble breathing.
• Vision Changes: Some people may experience vision changes or problems.
• Muscle Spasms: Some users report muscle spasms.
• Urinary Issues: Problems such as frequent urination or difficulty urinating may occur.

If you experience any severe or persistent side effects, it’s important to contact your healthcare provider promptly. They can help determine if Ampyra is the right medication for you and adjust your treatment plan as needed.

What should I know about storage and disposal of this medication?

Storage and Disposal of Ampyra:

• Storage:
  • Store Ampyra at room temperature, typically between 68°F to 77°F (20°C to 25°C).
  • Keep it away from moisture and heat. Store it in its original container, tightly closed.
  • Ensure that the medication is kept out of reach of children and pets.
• Disposal:
  • Dispose of unused or expired medication properly. Do not flush it down the toilet or pour it into a drain unless instructed to do so.
  • Check if there are any local drug take-back programs or pharmacies with medication disposal programs. These programs are often the safest way to dispose of unused medication.
  • If no take-back programs are available, follow any specific instructions provided by your pharmacist or contact your local waste disposal facility for guidance.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms of an overdose may include severe dizziness, seizures, or other serious side effects.

• Contact Emergency Services: If you suspect an overdose or experience severe symptoms, seek emergency medical help immediately.
• Call Poison Control: You can also contact your local poison control center for guidance.

What other information should I know?

• Regular Monitoring: Regular check-ups with your healthcare provider are important to monitor for side effects and assess the effectiveness of the medication.
• Avoid Alcohol: Be cautious with alcohol consumption, as it can potentially increase the risk of side effects such as dizziness.
• Medical History: Keep your healthcare provider informed about your full medical history, including any other conditions you have or medications you are taking.
• Pregnancy and Breastfeeding: Discuss the use of Ampyra with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as its effects in these situations are not well-established.

Always follow your healthcare provider’s instructions and consult them if you have any questions or concerns about your medication.