PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Amphotericin B Liposomal Injection

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Injections of amphotericin B are used to treat certain people’s visceral leishmaniasis, a parasite disease that typically affects the spleen, liver, and bone marrow, as well as fungal infections such cryptococcal meningitis, a fungus that infects the lining of the spinal cord and brain. Additionally, it is used to treat specific fungal infections in patients who cannot get amphotericin B traditional therapy. The drug amphotericin B liposomal injection belongs to the class of drugs known as antifungals. It functions by inhibiting the development of infection-causing fungus.

How should this medicine be used?

Amphotericin B liposomal injection is available as a liquid suspension for intravenous administration (into a vein). It is typically administered intravenously once daily, or on specified days for the treatment of leishmaniasis, over the course of two hours. If earlier dosages were well tolerated, this medicine may be administered over the course of an hour. Your general health, how well you handle the drug, and the kind of infection you have will all affect how long it takes you to get better.

Amphotericin B liposomal complex injection may cause a response in some patients. The severity of these responses increases with the first few doses and often occurs 1 to 3 hours following the commencement of your infusion. Other drugs may be recommended by your doctor to lessen these side effects. When receiving an injection of the amphotericin B liposomal complex, report any of the following symptoms to your doctor right away: fever, chills, nausea, vomiting, flushing, back pain with or without chest tightness, chest pain, shortness of breath, breathing issues, or a rapid, irregular, or pounding heartbeat.

Amphotericin B liposomal injection can be administered in a hospital or used at home. Your doctor will demonstrate how to administer amphotericin B liposomal injection if you plan to use it at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional. If you experience any difficulties administering the amphotericin B liposomal injection, consult your healthcare practitioner for advice.

Tell your doctor if, after obtaining an injection of amphotericin B, your symptoms do not get better or worse. After finishing the amphotericin B liposomal injection, let your doctor know if you continue to have signs of infection.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving amphotericin B liposomal injection,

  • If you have an allergy to amphotericin B, any other medications, or any of the chemicals in amphotericin B liposomal injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: Antifungals like clotrimazole, fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), and miconazole (Oravig, Monistat); drugs used to treat cancer; corticotropin (H.P. Acthar Gel); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); (Rayos). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you are undergoing leukocyte (white blood cell) transfusions, let your doctor know.
  • If you have renal illness now or ever have, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you conceive while having an injection of amphotericin B. While getting an injection of amphotericin B, refrain from breastfeeding.
  • Inform your doctor or dentist that you are receiving an amphotericin B liposomal injection if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

Side effects from amphotericin B liposomal injection are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Abdominal pain
  • Heartburn
  • Diarrhea
  • Constipation
  • Reduced appetite
  • At the injection site, there is redness or swelling
  • Light skin
  • Breathing difficulty
  • Dizziness
  • Headache
  • Having cold hands and feet

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Rash
  • Hives
  • Having trouble breathing
  • Itching
  • Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
  • Stiffness or pain in the chest
  • Seats that are dark and tarry
  • Less urinations
  • Urine with blood in it

Other negative effects of amphotericin B liposomal injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. During your therapy, your doctor may request a few lab tests to monitor how your body is reacting to the amphotericin B liposomal injection.

Inform the lab staff and your doctor that you are receiving an amphotericin B liposomal injection prior to any laboratory test.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • AmBisome®
Copyright © 2023