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Amphotec (Generic Amphotericin B Lipid Complex Injection)

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Why is this medication prescribed?

For those who did not respond to or were unable to take traditional amphotericin B therapy, significant, potentially life-threatening fungal infections are treated with amphotericin B lipid complex injection. The drug amphotericin B lipid complex injection belongs to the class of drugs known as antifungals. It functions by inhibiting the development of infection-causing fungus.

How should this medicine be used?

Amphotericin B lipid complex injection is available as a liquid suspension for intravenous administration (into a vein). It is typically intravenously administered (slowly injected) once every day. Your general health, how well you handle the drug, and the kind of infection you have will all affect how long it takes you to get better.

Amphotericin B lipid complex injectable side effects are possible and often appear 1 to 2 hours after the start of your infusion. When receiving the initial few doses of amphotericin B lipid complex, these responses are typically more frequent and severe. Other drugs may be recommended by your doctor to lessen these side effects. If you have any of the following symptoms after receiving an injection of amphotericin B lipid complex, call your doctor right away: fever, chills, nausea, vomiting, shortness of breath, breathing issues, chest discomfort, dizziness, loss of consciousness, or a rapid, erratic, or pounding heartbeat.

Amphotericin B injections are available in hospitals, or patients can take the drug themselves. Your doctor will demonstrate how to administer the drug to you if you will be administering amphotericin B lipid complex injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional. If you experience any difficulties injecting amphotericin B lipid complex injection, consult your healthcare practitioner for advice.

Inform your doctor if your symptoms persist or worsen while receiving amphotericin B lipid complex. After receiving the amphotericin B lipid complex injection, let your doctor know if you continue to have signs of infection.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving amphotericin B lipid complex injection,

  • If you have an allergy to amphotericin B, any other drugs, or any of the chemicals in amphotericin B lipid complex injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: medications for the treatment of cancer; corticotropin (H.P. Acthar Gel); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); flucytosine (Ancobon); pentamidine (Nebupent, Pentam); aminoglycoside antibiotics such as amikacin, gentamicin, or tobramycin (Bethkis, Kitabis Pak, Tobi); antifungals such (Retrovir, in Combivir, in Trizivir). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • If you are undergoing leukocyte (white blood cell) transfusions, let your doctor know.
  • If you have renal illness now or ever have, let your doctor know.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you conceive while having an injection of amphotericin B lipid complex. While getting an amphotericin B complex lipid injection, refrain from breastfeeding.
  • Inform your surgeon or dentist that you are receiving an injection of the amphotericin B lipid complex if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

There could be negative effects from injecting amphotericin B lipid complex. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Stomach cramps or discomfort
  • Heartburn
  • Diarrhea
  • Loss of weight
  • Reduced appetite
  • Joint or muscle ache
  • Edoema or redness at the injection site
  • Light skin
  • Breathing difficulty
  • Dizziness
  • Headache
  • Having cold hands and feet

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

  • Rash
  • Blistered skin
  • Wheezing
  • Having trouble breathing
  • Itching
  • Face, throat, tongue, lips, and eye swelling
  • Bloody poop
  • Seats that are dark and tarry
  • Stool with blood
  • The skin or eyes turning yellow
  • Less urinations

Other negative effects of amphotericin B lipid complex injection are possible. If you have any strange side effects while taking this medicine, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What other information should I know?

Keep all of your appointments with your physician and the lab. In order to monitor your body’s reaction to the amphotericin B lipid complex injection, your doctor will prescribe a number of blood tests throughout your treatment.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Abelcet®
  • Amphotec®
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