Why is this medication prescribed

Amitiza is a medication used primarily to treat chronic constipation and irritable bowel syndrome with constipation (IBS-C). It works by increasing the amount of fluid in the intestines, which helps to soften stool and stimulate bowel movements. It may also be prescribed for opioid-induced constipation in certain cases. It works by increasing fluid secretion in the intestines, which helps to soften stool and promote bowel movements.

How should this medicine be used?

Here are key points on how Amitiza is used:

• Dosage: Amitiza is usually taken orally in the form of a capsule. The typical dose is 8 mcg or 24 mcg twice daily, depending on the condition being treated. Your doctor will determine the appropriate dosage for you.
• Administration: Take Amitiza with food to help reduce the risk of gastrointestinal side effects, such as nausea. Swallow the capsule whole with water; do not crush, chew, or dissolve it.
• Consistency: Take the medication at the same times each day to help remember your doses.
• Follow Instructions: Adhere to the dosage and frequency prescribed by your healthcare provider. Do not adjust the dose or frequency without consulting them.

If you have any concerns or experience side effects, it’s important to discuss them with your healthcare provider.

Other uses for this medicine

In addition to its primary uses, Amitiza (Lubiprostone) is sometimes prescribed for:

• Constipation-Predominant Irritable Bowel Syndrome (IBS-C): Especially in women.
• Opioid-Induced Constipation: For patients using opioids who have not responded to other treatments.

What special precautions should I follow?

Special Precautions for Amitiza:

• Pregnancy and Breastfeeding: Amitiza should be used during pregnancy only if clearly needed. It is not known if Amitiza passes into breast milk, so consult your doctor if you are breastfeeding.
• Kidney or Liver Issues: If you have severe kidney or liver disease, your doctor might need to adjust your dose or monitor you more closely, as these conditions can affect how the drug is processed in your body.
• Dehydration: Ensure you stay hydrated, as Amitiza increases fluid in the intestines, and dehydration can worsen side effects.
• Intestinal Obstruction: Inform your doctor if you have a history of bowel obstruction or severe gastrointestinal conditions, as Amitiza may not be suitable in such cases.
• Allergies: Notify your doctor of any allergies, particularly if you have a history of allergic reactions to other medications.

Always follow your healthcare provider’s instructions and discuss any concerns or side effects with them.

What special dietary instructions should I follow?

• Stay Hydrated: Drink plenty of fluids to help prevent dehydration, as Amitiza increases fluid in the intestines.
• Balanced Diet: Maintain a well-balanced diet with fiber to support bowel health, but consult your doctor or dietitian if you have specific dietary concerns or restrictions.

What should I do if I forget a dose?

• Missed Dose: If you miss a dose of Amitiza, take it as soon as you remember.
• Skipping a Dose: If it’s almost time for your next dose, skip the missed dose; do not double up to make up for a missed dose.

What side effects can this medication cause?

Amitiza (Lubiprostone) can cause several side effects, though not everyone experiences them. Common and less common side effects include:

Common Side Effects:

• Nausea: This is the most frequent side effect. Taking Amitiza with food may help reduce nausea.
• Diarrhea: Increased bowel movements can occur.
• Abdominal Pain or Discomfort: Some people may experience stomach cramps or discomfort.
• Headache: Mild to moderate headaches can occur.

Less Common Side Effects:

• Vomiting: Though less common, some individuals may experience vomiting.
• Gas or Bloating: Some people might have increased gas or a feeling of bloating.
• Fatigue: Feeling unusually tired or fatigued.
• Dizziness: Rarely, Amitiza can cause dizziness or lightheadedness.
• Chest Pain: If you experience chest pain or tightness, seek medical attention immediately, as this can be a serious symptom.

Severe Side Effects: If you experience any of the following, contact your healthcare provider immediately:

• Severe Abdominal Pain: Intense or persistent pain may need evaluation.
• Severe Diarrhea: Persistent diarrhea can lead to dehydration.
• Allergic Reactions: Signs include rash, itching, swelling, severe dizziness, or trouble breathing.

Always report any side effects you experience to your healthcare provider to ensure appropriate management and to determine if Amitiza is the right medication for you.

What should I know about storage and disposal of this medication?

Storage and Disposal of Amitiza:

• Storage: Store Amitiza at room temperature, away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children.
• Disposal: Do not flush Amitiza down the toilet or pour it into a drain. Follow your pharmacist’s instructions for disposal, or use a drug take-back program if available. Check if your pharmacy has a medication disposal program.

In case of emergency/overdose

• Symptoms of Overdose: Symptoms might include severe diarrhea, severe abdominal pain, nausea, or vomiting.
• What to Do: If you suspect an overdose, contact emergency services or go to the nearest emergency room immediately. You can also call Poison Control for advice (in the U.S., the number is 1-800-222-1222).

What other information should I know?

• Dosage: Follow the prescribed dosage carefully. Do not take more or less than directed.
• Interactions: Inform your healthcare provider about all other medications and supplements you are taking, as Amitiza may interact with certain drugs.
• Consult Your Doctor: Before starting Amitiza, discuss any pre-existing conditions or concerns with your healthcare provider.
• Medical Follow-Up: Regular follow-up with your healthcare provider may be necessary to monitor the medication’s effectiveness and adjust the dosage if needed.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about using Amitiza.