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Amikacin Injection

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WARNING

Amikacin may seriously damage the kidneys. People who are older or who are dehydrated may experience kidney difficulties more frequently. If you have renal illness now or ever have, let your doctor know. Call your doctor right away if you have any of the following symptoms: reduced urination, face, arm, hand, foot, ankle, or lower leg edoema, unusual fatigue, or weakness.

Amikacin may result in severe hearing issues. People who are older or who are dehydrated may experience hearing issues more frequently. In rare circumstances, hearing loss could be permanent. If you have or have ever experienced vertigo, hearing loss, or ringing in the ears, let your doctor know. Call your doctor right away if you suffer any of the following symptoms: dizziness, roaring or ringing in the ears, or hearing loss.

Nerve issues could result from amikacin. Inform your doctor if you experience or have ever experienced seizures, muscle twitching or weakening, burning, tingling, or numbness in your hands, arms, feet, or legs.

You run a higher chance of developing major kidney, hearing, or other health issues if you use certain drugs. Inform your doctor and pharmacist if you are taking any of the following medications: cisplatin; colistin (Coly-Mycin S); bacitracin; amphotericin (Abelcet, Ambisome, Amphotec); bacitracin; capreomycin (Capastat); certain cephalosporin antibiotics like cefazolin (Ancef, Kefzol), cefixime (Suprax), or cephalexin (Keflex); gentamicin, kanamycin, neomycin (Neo-Fradin), paromomycin, streptomycin, or tobramycin; polymyxin B; or vancomycin. Cyclosporine (Gengraf, Neoral, Restasis, Sandimmune); diuretics (‘water pills’) such as bumetanide, ethacrynic acid (Edecrin), furosemide (Lasix), or (Vanocin). The injection of amikacin may not be recommended by your doctor.

Inform the surgeon or dentist that you are using the amikacin injection if you are having surgery, including dental surgery.

Keep all of your appointments with your physician and the lab. Before and during treatment, your doctor will prescribe specific tests, such as hearing tests, to monitor your body’s reaction to amikacin.

Why is this medication prescribed?

Meningitis, an infection of the membranes that surround the brain and spinal cord, as well as infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary system are among the dangerous bacterial diseases that are treated with amikacin injection. Amikacin injection belongs to the group of drugs known as aminoglycoside antibiotics. It eliminates bacteria to operate.

Colds, the flu, or other viral diseases cannot be treated with antibiotics such as amikacin injection. Antibiotic use that is not necessary raises the likelihood of developing a later infection that is resistant to antibiotic treatment.

How should this medicine be used?

Every 8 or 12 hours, a liquid form of the antibiotic amikacin injection is administered intravenously or intramuscularly (two or three times a day). Amikacin is typically infused (slowly given) intravenously over the course of 30 to 60 minutes. The sort of infection you have will determine how long your therapy will last.

Amikacin injections can be administered either in a hospital setting or at home. Your healthcare practitioner will demonstrate how to administer the drug if you will be receiving amikacin injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

During the initial days of amikacin injectable therapy, you should start to feel better. Call your doctor if your symptoms don’t go away or get worse.

Even if you feel better, keep using the amikacin injection until the prescription is finished. Your illness could not be entirely treated if you stop using amikacin injection too soon or skip doses, and the bacteria might develop an antibiotic resistance.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Amikacin is occasionally used with other drugs to treat tuberculosis (TB; a serious infection that affects the lungs and sometimes other parts of the body). The dangers of using this drug for your illness should be discussed with your doctor.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before receiving amikacin injection,

  • Inform your doctor and pharmacist if you have any allergies to sulfites, any medicines, any of the chemicals in amikacin injection, other aminoglycoside antibiotics such gentamicin, kanamycin, neomycin, streptomycin, or tobramycin. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, and dietary supplements you are currently taking or intend to take. Mention the medications in the IMPORTANT WARNING section as well as any of the following: dimenhydrinate (Dramamine); meclizine (Bonine); or nonsteroidal anti-inflammatory drugs like indomethacin. Other antibiotics include amoxicillin (Amoxil, Larotid, Moxatag, in Augmentin, in Prevpac); ampicillin; or penicillin (Indocin, Tivorbex). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medications you are taking, even any not on this list, since many other drugs may also interact with amikacin.
  • Inform your doctor if you suffer from myasthenia gravis, Parkinson’s disease, or cystic fibrosis, an illness that affects the muscles and digestive system and is inherited.
  • If you are pregnant, want to become pregnant, or are currently nursing, let your doctor know. Dial your doctor right away if you get pregnant while taking amikacin injection. The foetus could suffer from amikacin.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

Amikacin could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Fever

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT WARNING section:

  • Rash
  • Skin that is flaking or blistering
  • Itching
  • Hives
  • Swelling of the lips, tongue, throat, eyes, or face
  • Breathing or swallowing challenges
  • Hoarseness
  • Severe diarrhoea (watery or bloody faeces), which may or may not be accompanied by fever and cramping in the stomach (may occur up to 2 months or more after your treatment)

Amikacin may result in additional adverse effects. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Amikin®
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