Migraine headache symptoms are treated with nariptan (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light). The drug naratriptan belongs to a group of drugs known as selective serotonin receptor agonists. It functions by constricting blood arteries surrounding the brain, preventing pain signals from reaching the brain, and halting the release of several naturally occurring chemicals that produce pain, nausea, and other migraine symptoms. Naratriptan does not lessen the frequency of headaches or stop migraine attacks.

Naratriptan is available as an oral tablet. It is typically given as soon as a migraine headache appears. You may take a second pill if your symptoms become better after taking naratriptan but come back after four hours or more. However, do not take a second pill of naratriptan before calling your doctor if your symptoms do not get better after you take it. The maximum amount of pills you can take in a day will be specified by your doctor. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Naratriptan should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

The first time you take naratriptan, you may do it in a clinic or other medical setting where you can be watched closely for negative side effects.

If your headaches do not improve or become more regular after taking naratriptan, contact your doctor right away.

Your headaches could worsen or happen more frequently if you use naratriptan more regularly or for a longer duration than advised. Naratriptan and other headache medications shouldn’t be taken more than 10 days a month. If you need to take naratriptan to cure more than four headaches within a month, call your doctor.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

Before taking naratriptan,

• If you have an allergy to naratriptan, any other drugs, or any of the ingredients in naratriptan tablets, tell your doctor and pharmacist right away. Request a list of the components from your pharmacist.
• If you have taken any of the following drugs within the previous 24 hours, avoid taking naratriptan: other selective serotonin receptor agonists, such as sumatriptan (Imitrex, in Treximet), zolmitriptan (Zomig), almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), and rizatriptan (Maxalt); ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Cafergot, Ergomar), methylergonovine (Methergine), methysergide (Sansert), and pergolide, or ergot-type drugs such as bromocriptine (Parlodel), cabergoline, dihydroergotamine (D.H.E. 45, Migran (Permax).
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: antidepressants like imipramine (Tofranil), amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), protriptyline (Vivactil), and trimipramine (Surmontil); as well as acetaminophen (Tylenol). Oral contraceptives (birth control pills); SSRIs like citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Motrin) and selective serotonin/norepinephrine reuptake inhibitors (SNRIs), which include venlafaxine (Venlafaxine), duloxetine (Cymbalta), sibutramine (Meridia), and desvenlafaxine (Effexor). Also let your doctor or pharmacist know if you’ve recently stopped taking any of the following drugs: tranylcypromine, isocarboxazid, phenelzine, selegiline, and phenelzine (Nardil), as well as isocarboxazid (Marplan) (Parnate). If you are taking medication, your doctor may need to adjust the dosage or keep a closer eye out for any negative effects.
• Inform your doctor if you have or have ever had heart disease, a heart attack, angina (chest pain), irregular heartbeats, a stroke or “mini-stroke,” circulation issues like varicose veins, leg blood clots, Raynaud’s disease (problems with blood flow to the fingers, toes, ears, and nose), or ischemic bowel disease (bloody diarrhoea and stomach pain brought on by decreased blood flow to the intestines); Your physician might advise against taking naratriptan.
• Inform your doctor if you smoke, are obese, have ever had high blood pressure, diabetes, high cholesterol, renal, or liver illness, have recently experienced menopause (a change in your hormonal balance), or if any members of your family currently have or have ever had heart disease or a stroke.
• If you are breastfeeding a child or intend to become pregnant, let your doctor know. If you intend to engage in sexual activity while taking this medicine, discuss birth control options with your doctor. Call your doctor if you become pregnant while taking naratriptan.
• You need to be aware that naratriptan might make you feel sleepy. Prior to understanding how this drug affects you, avoid using machinery or driving a car.
• To determine whether a migraine is to blame for your headaches, discuss them with your physician. Certain forms of migraine headaches, such as basilar or hemiplegic migraines, should not be treated with naratriptan (such as cluster headaches).

There may be negative effects from naratriptan. If any of these symptoms are severe or do not go away, let your doctor know right once:

1. Weakness
2. Tiredness
3. Uneasy stomach
4. Nausea
5. Dizziness
6. Warmth or coldness

Some adverse effects can be very harmful. Call your doctor right away if you encounter any of these symptoms, or seek emergency care:

• Chest, throat, neck, or jaw tightness, pain, pressure, or weight
• Irregular, hammering, or quick heartbeat
• Breathing difficulty
• Started to get a cold sweat
• Lightheadedness
• Weakness, numbness, or a leg or an arm
• Slow or challenging speech
• Breathing or swallowing challenges
• Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
• Hoarseness
• Hives
• Rash
• Itching
• Strong or sudden stomach discomfort
• Bloody stools
• Constipation
• Vomiting
• Fingers or toes that are pale or have a blue tint
• Having tingling, burning, or pain in your hands or feet

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Symptoms of overdose may include the following:

• Lightheadedness
• A sore neck
• Tiredness
• Inability to coordinate
• Chest pain

Keep all of your doctor’s appointments. Regular blood pressure checks are advised.

When you experience headaches and when you take naratriptan, you should record such events in a headache journal.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.