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Altretamine

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WARNING

Altretamine may seriously harm your nerves. Call your doctor right away if you have any of the following symptoms: Changes in mood, loss of consciousness, or pain, burning, numbness, or tingling in the hands or feet, weakness in the arms or legs, or the inability to move your arms or legs.

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to altretamine, your doctor will prescribe a number of tests both before and during your therapy.

Why is this medication prescribed?

Altretamine is used to treat cancer of the ovaries (cancer that starts in the female reproductive organs where eggs are created) when other drugs haven’t worked or when the condition has gotten worse. Antineoplastic agents are a group of drugs that includes the drug altretamine. It operates by reducing or preventing the growth of cancer cells within your body.

How should this medicine be used?

Altretamine is available as a pill to be swallowed. It is typically taken for 14 to 21 days straight, four times a day (a dose after each meal and a dose before bedtime). Depending on how you react to the drug, this cycle can be repeated once every four weeks. Take altretamine every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take altretamine as prescribed by your doctor. Never take it in larger or less amounts or more frequently than directed by your doctor.

Depending on how you respond to the medication and any adverse effects you experience, your doctor may change the dosage of altretamine you are taking. Discuss your feelings regarding your treatment with your doctor. Never discontinue taking altretamine without consulting your physician first.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking altretamine,

  • Inform your doctor and pharmacist if you have any allergies prior to using altretamine, whether to the drug, any other medications, or any of the components in the capsules. Request a list of the components from your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: pyridoxine (Vitamin B6), cimetidine (Tagamet), isocarboxazid (Marplan), phenelzine (Nardil), and tranylcypromine (Parnate). Inform your doctor if you have ever had or taken any of the following chemotherapy drugs: cisplatin (Platinol), bendamustine (Treanda), carmustine (BiCNU, Gliadel Wafer), cyclophosphamide (Cytoxan), ifosfamide (Ifex), lomustine (CeeNU), melphalan (Alkeran), procarbazine (Mutalane), tem Your doctor may need to keep a close eye out for any negative effects.
  • If you suffer from blood or nervous system diseases, let your doctor know. Your doctor might advise against taking altretamine.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. While taking altretamine, you should not get pregnant or breastfeed. Call your doctor if you become pregnant while taking altretamine. The foetus could suffer from altretamine.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

Altretamine might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Reduced appetite
  • Unusual weakness or fatigue
  • Dizziness
  • Light skin
  • Fainting
  • Itching
  • Skin rash
  • Hair fall

Some adverse effects can be very harmful. Call your doctor right away or seek emergency medical attention if you develop any of these signs or any of the ones detailed in the IMPORTANT WARNING section:

  • Fever, chills, sore throat, persistent cough, congestion, or other indicators of infection
  • Uncommon bruising or bleeding
  • Tarry, black, or bloody stools
  • Bloody poop
  • Vomited substance that resembles coffee grounds
  • Bluish gums
  • Small, rounded skin patches that are red or purple in colour

Other negative effects of altretamine are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Hexalen®
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