WARNING

Taking Altretamine involves several risks:

• Bone Marrow Suppression: Can lead to anemia, increased risk of infections, and bleeding due to reduced blood cell counts.
• Gastrointestinal Issues: Includes nausea, vomiting, and loss of appetite, which can affect overall health and nutrition.
• Liver Function: Can impact liver function, requiring regular monitoring to avoid serious liver-related issues.
• Neurological Effects: Rarely, can cause confusion or changes in mental status.
• Allergic Reactions: Possible, including rash, itching, or other severe reactions.

It’s crucial to monitor for these risks and consult your healthcare provider for regular check-ups and to manage any adverse effects.

Why is this medication prescribed?

Altretamine is prescribed primarily for the treatment of certain types of cancer, especially in cases where other treatments have not been effective. It is commonly used for:

• Ovarian Cancer: Altretamine is used in the treatment of advanced or recurrent ovarian cancer.
• Other Cancers: It might be used off-label for other types of cancer depending on the specific case and clinical judgment.

How should this medicine be used?

Here’s a general guide on how Altretamine is used:

• Dosage and Administration: It is typically taken orally in the form of tablets. The specific dosage and frequency depend on the individual’s condition, overall health, and response to treatment. Your doctor will prescribe the exact dosage.
• Usage Instructions: It’s important to follow the dosage instructions provided by your healthcare provider closely. Take the medication with food to minimize gastrointestinal discomfort, and make sure to swallow the tablets whole, do not crush or chew them.
• Monitoring and Adjustments: Regular check-ups with your doctor are necessary to monitor your response to the medication and to adjust the dosage if needed.
• Side Effects: Be aware of potential side effects, which can include nausea, vomiting, and bone marrow suppression. Report any severe or persistent side effects to your healthcare provider.

Always follow your healthcare provider’s instructions and guidelines when taking Altretamine

Other uses for this medicine

Altretamine is primarily used for treating ovarian cancer, but its use can extend to other cancers in specific situations, often as part of combination therapy or when other treatments are not effective. Its use can be tailored based on individual patient needs and responses.

What special precautions should I follow?

Special Precautions:

• Blood Tests: Regular blood tests are necessary to monitor blood cell counts and liver function, as Altretamine can affect bone marrow and liver function.
• Pregnancy and Breastfeeding: Altretamine can be harmful to a developing fetus and is not recommended during pregnancy. It’s also advised not to breastfeed while taking this medication.
• Drug Interactions: Inform your healthcare provider about all other medications you are taking, including over-the-counter drugs and supplements, as Altretamine can interact with other medications.
• Allergies and Sensitivities: Make sure your doctor is aware of any allergies or sensitivities you have. This medication can cause allergic reactions or exacerbate pre-existing conditions.
• Liver and Kidney Function: If you have liver or kidney issues, discuss these with your healthcare provider, as Altretamine may require dose adjustments or extra monitoring.
• Avoid Infection: Altretamine can lower your immune system’s ability to fight infections. Take precautions to avoid exposure to infections and report any signs of infection to your doctor immediately.

Always consult your healthcare provider for specific advice and guidance tailored to your individual health needs.

What special dietary instructions should I follow?

• Take with Food: To minimize gastrointestinal irritation, take Altretamine with food. This helps in better absorption and reduces potential stomach upset.
• Hydration: Maintain adequate hydration by drinking plenty of fluids, which can help with side effects like nausea.
• Avoid Certain Foods: There are no specific dietary restrictions associated with Altretamine, but maintaining a balanced diet can help manage side effects and support overall health.

What should I do if I forget a dose?

• Timing: If you remember the missed dose soon after, take it as soon as you can. However, if it’s almost time for your next dose, skip the missed dose; do not double up to make up for a missed one.
• Consult Your Doctor: Always follow your healthcare provider’s instructions on what to do if you miss a dose. They can give you specific advice based on your treatment schedule.

What side effects can this medication cause?

Altretamine can cause a range of side effects. Common and potential side effects include:

• Nausea and Vomiting: These are common and can often be managed with anti-nausea medications.
• Loss of Appetite: This can lead to weight loss; maintaining a balanced diet and consulting with a nutritionist may help.
• Fatigue: Feeling tired or weak is a common side effect. Rest and good nutrition can help manage fatigue.
• Bone Marrow Suppression: This can lead to anemia, leukopenia (low white blood cell count), and thrombocytopenia (low platelet count), increasing the risk of infections, bleeding, and bruising.
• Gastrointestinal Issues: This includes abdominal pain, diarrhea, and constipation.
• Hair Loss: Some people may experience hair thinning or loss.
• Mouth Sores: Painful sores in the mouth may occur.
• Skin Changes: Skin rash or itching can happen.
• Liver Function Changes: Increased liver enzyme levels can be a side effect, so regular monitoring is essential.
• Neurological Effects: In rare cases, Altretamine can cause neurological symptoms such as confusion or changes in mental status.

It’s important to report any new or severe side effects to your healthcare provider promptly. They can provide guidance on managing side effects and make adjustments to your treatment plan if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Altretamine:

• Storage:
  • Store Altretamine at room temperature, away from excessive heat and moisture.
  • Keep it in its original container, tightly closed, and out of reach of children and pets.
  • Do not store it in the bathroom or any place with high humidity.
• Disposal:
  • Follow specific disposal instructions provided by your pharmacist or healthcare provider. Many pharmacies have medication take-back programs.
  • If no take-back program is available, you can dispose of Altretamine in household trash by mixing it with an undesirable substance (like used coffee grounds) in a sealed bag. Do not flush it down the toilet unless instructed to do so.

In case of emergency/overdose

• Contact Emergency Services: If you suspect an overdose, contact emergency services or go to the nearest emergency room immediately.
• Provide Information: Be prepared to provide information about the amount of medication taken and the time of ingestion.
• Symptoms of Overdose: Symptoms can include severe nausea, vomiting, dizziness, and confusion. Seek medical attention if these or other severe symptoms occur.

What other information should I know?

• Regular Check-ups: Regular visits to your healthcare provider are crucial for monitoring your response to treatment and managing any side effects.
• Patient Education: Make sure you understand how to take the medication correctly and what to do if you miss a dose or experience side effects.
• Emergency Contact: Keep contact information for your healthcare provider and local poison control center readily available.
• Medication List: Maintain a list of all medications you are taking and share it with your healthcare provider to avoid potential drug interactions.
• Support Resources: Consider joining support groups or counseling services if you need additional help managing the emotional and psychological aspects of cancer treatment.