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Why is this medication prescribed?

In order to lower blood sugar levels in people with type 2 diabetes, alogliptin is used in conjunction with diet and exercise (condition in which blood sugar is too high because the body does not produce or use insulin normally). The drug analogliptin belongs to the group of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. In order to manage blood sugar, it works by increasing the body’s insulin production. Alogliptin is not used to treat diabetic ketoacidosis or type 1 diabetes, a condition in which the body does not create insulin and cannot regulate the quantity of sugar in the blood (a serious condition that may develop if high blood sugar is not treated).

People with diabetes and high blood sugar over time may experience serious or fatal complications, such as heart disease, stroke, kidney issues, nerve damage, and vision issues. It may be possible to control your diabetes and enhance your health by taking medication(s), making lifestyle changes (such as diet, exercise, and quitting smoking), and monitoring your blood sugar frequently. This treatment may also lower your risk of heart attack, stroke, kidney failure, nerve damage (resulting in numb, cold legs or feet and diminished sex capacity in both men and women), eye issues, such as changes in eyesight or blindness, or gum disease, which are all symptoms of diabetes. The optimal strategy to manage your diabetes will be discussed with you by your doctor and other healthcare professionals.

How should this medicine be used?

An oral pill is available for analogliptin. It is typically taken once day, with or without food. Alogliptin should be taken every day at about the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Administer alogliptin precisely as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Although it manages diabetes, analogliptin does not treat it. Even if you are feeling fine, keep taking alogliptin. Without consulting your doctor, do not discontinue taking alogliptin.

You will get the manufacturer’s patient information sheet (Medication Guide) from your physician or pharmacist when you start taking alogliptin and each time you refill your prescription. If you have any questions, carefully read the material and contact your doctor or pharmacist. The Medication Guide is also available on the manufacturer’s website or the Food and Drug Administration (FDA) website (

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking alogliptin,

  • Alogliptin, other DPP-4 inhibitors like linagliptin (Tradjenta, in Glyxambi, in Jentadueto), saxagliptin (Onglyza, in Kombiglyze), or sitagliptin (Januvia, in Janumet), any other medications, or any of the ingredients in alogliptin tablets should all be disclosed to your doctor and pharmacist if you have any of these allergies. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Mentioning insulin and other diabetes meds is important. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you regularly consume significant amounts of alcohol, have ever experienced pancreatitis (pancreas swelling), have gallstones, are experiencing heart failure, or have kidney or liver illness.
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor right away if you get pregnant while taking alogliptin.
  • You should let your doctor or dentist know if you are taking alogliptin if you are having surgery, including dental surgery.
  • Consult your doctor for advice on what to do in the event of an injury, fever, or illness. Your blood sugar levels and the potential dosage of alogliptin may be impacted by these disorders.

What special dietary instructions should I follow?

Make sure to abide by all dietary and exercise advice given to you by your physician or nutritionist. It’s crucial to maintain a nutritious diet, exercise frequently, and, if required, reduce weight. Your diabetes will be easier to manage as a result, and alogliptin will function more efficiently.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it if you miss one. If your next dose is approaching, skip the missed one and resume your regular dosing schedule. Do not take a second dose to make up for a missed one.

What side effects can this medication cause?

Your blood sugar levels may alter as a result of this drug. You ought to be aware of the signs of high and low blood sugar as well as what to do in case you experience these symptoms.

Side effects with analogliptin are possible. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Headache
  • Runny or stuffed nose
  • Unwell throat
  • Aching joints

Some adverse effects can be very harmful. Stop taking alogliptin and call your doctor right away if you develop any of these symptoms, or seek emergency medical attention:

  • Serious abdominal pain that could radiate to your back
  • Vomiting
  • Excessive fatigue
  • Reduced appetite
  • Stomach pain in the right upper region
  • Dark faeces
  • Skin or eyes turning yellow
  • Fever
  • Blisters
  • Peeling skin
  • Rash
  • Hives
  • Itching
  • Eye, face, lip, tongue, or throat swelling
  • Hoarseness
  • Breathing or swallowing challenges
  • Breathing difficulties, especially when resting down
  • Swelling in the ankles, legs, or feet
  • Unexpected weight gain


Other negative effects of analogliptin are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how well your body is responding to alogliptin, your doctor may likely request a number of laboratory tests. Regular blood sugar and glycosylated haemoglobin (HbA1c) checks are advised to monitor your alogliptin response. Your physician could also provide instructions on how to measure your blood or urine sugar levels at home in order to monitor your response to alogliptin. Pay close attention to these guidelines.

Wearing a diabetes identity bracelet will ensure that you receive the right care in an emergency.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Nesina®
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