For the treatment of seasonal allergic rhinitis (also known as “hay fever”), which manifests as runny nose, sneezing, congestion (stuffy nose), red, itchy, or watery eyes, or irritation of the nose, throat, or roof of the mouth, fexofenadine and pseudoephedrine are combined. The drug fexofenadine belongs to the antihistamine drug class. It functions by obstructing histamine’s actions, a chemical in the body that produces allergy symptoms. Pseudoephedrine belongs to the group of drugs known as decongestants. It functions by making the nasal passages dry.

A long-acting (extended-release) oral tablet containing fexofenadine and pseudoephedrine is available. The 12-hour fexofenadine and pseudoephedrine pill is typically taken once or twice day with water and an empty stomach. The 24-hour pill of fexofenadine and pseudoephedrine is typically taken once daily with water and an empty stomach. If you avoid taking fexofenadine and pseudoephedrine with fruit drinks like orange, grapefruit, or apple juice, they will work better. Fexofenadine and pseudoephedrine should be taken every day at about the same time(s). Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Fexofenadine and pseudoephedrine should be taken exactly as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Despite not curing seasonal allergic rhinitis, fexofenadine and pseudoephedrine manage its symptoms. Even if you feel OK and are not experiencing any symptoms, keep taking fexofenadine and pseudoephedrine. Your symptoms can worsen if you wait too long in between doses.

Do not chew, break, or crush the tablets; instead, swallow them whole.

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

Before taking fexofenadine and pseudoephedrine,

• If you have any allergies, including to fexofenadine (Allegra), pseudoephedrine (Sudafed, in Dimetapp, in Drixoral, and other products), other drugs, or any of the substances in the tablets, tell your doctor and pharmacist very away. Request a list of the components from your pharmacist.
• If you are currently taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), or tranylcypromine (Parnate), or have recently taken one, you should not take fexofenadine and pseudoephedrine.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: Dietary supplements, digoxin (Digitek, Lanoxin, Lanoxicaps), erythromycin (E.E.S., E-Mycin, Erythrocin), ketoconazole (Nizoral), methyldopa (Aldomet), reserpine (Serpalan, Serpasil, Serpatabs), over-the-counter antihistamines, decongestants, and stimulants are examples of common drugs Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Take the antacid several hours before or after taking the fexofenadine if you also take an antacid that contains aluminium or magnesium (Maalox, Mylanta, etc.).
• If you have glaucoma, difficulty urinating, high blood pressure, or coronary artery disease, let your doctor know (condition that occurs when the blood vessels of the heart are narrowed by fat or cholesterol deposits). Tell your doctor if you have experienced any of the following symptoms after taking an adrenergic medicine, such as phenylephrine (Neo-Synephrine) or epinephrine: sleeplessness, dizziness, weakness, uncontrollable shaking of a part of your body; rapid, pounding, or irregular heartbeat (Primatene Mist, EpiPen). Your physician might advise against taking fexofenadine and pseudoephedrine.
• Inform your doctor if you have diabetes, a heart attack, hyperthyroidism (an overactive thyroid gland), prostatic hypertrophy (an enlarged prostate), angina (chest discomfort or pressure), heart disease, or kidney illness.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking pseudoephedrine and fexofenadine.

You might want to consume fewer caffeinated beverages (coffee, tea, sodas, and energy drinks) if you are a sensitive person because they may exacerbate the restlessness and insomnia brought on by pseudoephedrine. Consult your doctor before consuming any of these liquids while taking this medicine.

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

Pseudoephedrine with fexofenadine may have negative side effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Nausea
• Abdominal pain
• Heartburn
• Mouth ache
• Throat annoyance
• Back ache
• Light skin

Some adverse effects can be very harmful. Even though the following signs are unusual, you should call your doctor right once if you notice any of them:

• Nervousness
• Dizziness
• Having trouble falling or staying asleep
• Weakness
• Fear, dread, or tension
• Hallucinating (seeing things or hearing sounds and voices that do not exist)
• Shaking of a body part that you are unable to control
• Seizure
• Fainting
• Distorted vision
• Hives
• Rash
• Itching
• Breathing or swallowing challenges
• Swelling of the lower legs, hands, feet, ankles, or face, neck, tongue, lips, eyes, or mouth
• Hoarseness
• Erratic or quickly beating heartbeat
• Difficulty or discomfort during urination

Other adverse effects from fexofenadine and pseudoephedrine are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

Keep this medication out of the reach of children and properly closed in its original container. Store it at room temperature, away from extreme heat and moisture (not in the bathroom).

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning. http://www.upandaway.org

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right away if the person has fallen, had a seizure, is having problems breathing, or cannot be roused.

Overdose symptoms could include:

• Dizziness
• Drowsiness
• Mouth ache
• Giddiness
• Headache
• Nausea
• Vomiting
• Sweating
• Thirst
• Hammering or rapid heartbeat
• Chest pain
• Having trouble breathing
• Having trouble urinating
• Muscle sluggishness or tension
• Nervousness
• Restlessness
• Having trouble falling or staying asleep
• Hallucinating (hearing voices or seeing objects that do not exist)
• Seizures
• Coma

You might detect anything that resembles a tablet in your stool if you’re taking fexofenadine and pseudoephedrine 12-hour pills. The fact that the tablet is empty does not imply that you did not take the whole prescribed amount of medication.

Keep all of your doctor’s appointments.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.