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Aliskiren

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WARNING

If you are expecting, do not take aliskiren. Inform your doctor as soon as possible if you become pregnant while taking aliskiren. The foetus may be harmed by aliskiren.

Why is this medication prescribed?

For the treatment of high blood pressure, aliskiren can be taken either on its own or in conjunction with other drugs. Aliskiren is a drug that belongs to the group of drugs called direct renin inhibitors. It functions by lowering a few naturally occurring chemicals that tighten blood arteries, allowing blood vessels to relax and the heart to flow blood more effectively.

Untreated high blood pressure often causes damage to the kidneys, brain, heart, blood vessels, and other organs. Damage to these organs may lead to heart disease, a heart attack, heart failure, a stroke, renal failure, vision loss, and other problems. In addition to taking medication, changing your lifestyle will help you control your blood pressure. These changes include giving up smoking, using alcohol sparingly, adhering to a low-fat and salt diet, maintaining a healthy weight, and working out for at least 30 minutes most days.

How should this medicine be used?

Aliskiren is available as a tablet for oral use. It is typically given once daily. Aliskiren should either be taken with meals exclusively or not at all while carrying anything. Take aliskiren every day at about the same time. Ask your doctor or pharmacist to explain any medication label instructions that you are unsure about following. Aliskiren should be taken as prescribed. Never use it in larger or smaller dosages or more frequently than directed by your physician.

Most likely, your doctor will start you on a low dose of aliskiren, and after at least two weeks, he or she may increase it.

Despite not being a drug for high blood pressure, aliskiren manages the condition. Even if you feel great, it is still advisable to take Aliskiren. Without first consulting your physician, do not discontinue taking aliskiren.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

If you think this medication ought to be used for something different, speak with your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking aliskiren,

  • If you have any allergies, including to aliskiren, other medicines, or any of the chemicals in ACE inhibitors such benazepril (Lotensin, in Lotrel), captopril (Capoten), enalapril (Vasotec, in Vaseretic), fosinopril, or lisinopril, tell your doctor and pharmacist right away (in Prinzide, in Zestoretic), mo Ask your pharmacist or check the patient information for a list of the ingredients.
  • If you are using an ACE inhibitor or an angiotensin receptor blocker (ARB), such as azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten, in Teveten HCT), irbesartan (Avapro, in Avalide), or losartan (Cozaar), and you have diabetes (high blood sugar Your doctor typically won’t allow you to take aliskiren if you have diabetes and are taking one of these medications.
  • Any additional prescription, over-the-counter, vitamin, dietary supplement, and herbal products you are now taking or intend to take should be disclosed to your doctor and pharmacist. Include one or more of the following: Aspirin, as well as other NSAIDs such as ibuprofen (Advil, Motrin), naproxen (Aleve), and some antifungals like itraconazole (Sporanox); celecoxib (Celebrex), cyclosporine (Gengraf, Neoral, Sandimmune), atorvastatin (Lipitor, in Caduet, Liptruzet), diuretics (‘water pills’), potassium supplements or medications containing potassium, and any other medications for high blood pressure or heart problems. Your doctor may need to change the dosage of your medications or closely monitor you for side effects.
  • Inform your physician if you have kidney illness, diabetes, seizures, a history of heart attacks, or heart failure.
  • If you intend to get pregnant or are presently nursing a child, let your doctor know. Stop breastfeeding if you are taking aliskiren.
  • You should be aware that conditions including diarrhoea, vomiting, dehydration, excessive perspiration, and inadequate hydration can cause blood pressure to drop, which can cause lightheadedness and fainting. Inform your doctor if you experience any of these problems or if any new ones arise while you are taking treatment.

What special dietary instructions should I follow?

Avoid eating a meal that is high in fat when taking aliskiren with it (such as fast food or fried meals). You shouldn’t use potassium supplements or salt substitutes without first speaking to your doctor.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. Skip the missed dose and resume your regular dosing plan if your next dose is soon to come. Never take two pills in place of one to replace two.

What side effects can this medication cause?

Possible side effects of aliskiren exist. Inform your doctor right once if any of these symptoms are severe or persistent:

  • Diarrhea
  • Continent pain
  • Heartburn
  • Cough
  • Rash
  • Dizziness
  • Headache
  • Back ache

Some negative effects may be quite detrimental. If you have any of the following symptoms while using aliskiren, stop using it and get immediate medical help:

  • Headaches and vertigo
  • Swelling of the lower legs, hands, feet, ankles, or hands as well as the face, neck, tongue, lips, eyes, or mouth
  • Blemished or dry skin
  • Hoarseness
  • Breathing or eating difficulties
  • Seizure
  • Irregular, sluggish, or slow heartbeat

There may be further adverse effects from aliskiren. Contact your doctor as soon as possible if you encounter any odd side effects while taking this medication.

What should I know about storage and disposal of this medication?

Keep this medication out of the reach of children and properly closed in its original container. Store it at room temperature, away from extreme heat and moisture (not in the bathroom). Do not take a desiccant (drying agent) out of the bottle if one has been provided.

To avoid pets, children, and other people eating unused medicines, they must be properly disposed of. However, flushing this drug down the toilet is not advised. The most straightforward method to dispose of your medication is to use a medicine take-back programme. Speak with your pharmacist or the waste/recycling agency in your city to learn more about take-back programmes in the area. Visit the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for further information if you do not have access to a take-back programme.

As many containers (such as weekly pill minders and those for eye drops, lotions, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always keep safety caps on and store drugs up and away from young children to prevent poisoning. http://www.upandaway.org

In case of emergency/overdose

In the event of an overdose, dial 1-800-222-1222 to contact poison control. Information is also available online at https://www.poisonhelp.org/help. If the person has fallen, had a seizure, is having trouble breathing, or cannot be awakened, immediately dial 911.

Overdose symptoms could include:

  • Fainting
  • Dizziness
  • Vision distortion
  • Nausea

What other information should I know?

Keep all of your appointments with the lab and your doctor. Your doctor could ask for lab testing to find out how your body is responding to aliskiren.

You shouldn’t let anyone else take your medicine. Your pharmacist should be contacted with any questions you may have about medicine refills.

Every medication you take, including over-the-counter (OTC) goods, prescription medications, and dietary supplements like vitamins and minerals, should be documented. When visiting a doctor or being admitted to the hospital, you should always have this list with you. In case of an emergency, you should always carry this information with you.

Brand names

  • Tekturna®
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