Why is this medication prescribed?

Advil PM is a combination medication that typically contains ibuprofen and diphenhydramine. Here’s why each component is included:

• Ibuprofen: It is a nonsteroidal anti-inflammatory drug (NSAID) used primarily to reduce inflammation and relieve pain. It is commonly used for conditions such as arthritis, menstrual cramps, headaches, dental pain, and muscular aches.
• Diphenhydramine: This is an antihistamine that is used primarily to treat allergy symptoms (such as itching, rash, hay fever, watery eyes) and also as a sleep aid due to its sedative effects. It can help induce sleepiness and improve sleep quality.

When these two medications are combined in Advil PM, the intention is to provide relief from pain and inflammation (due to ibuprofen) along with the ability to aid sleep (due to diphenhydramine). Therefore, Advil PM is often prescribed or recommended for individuals who experience pain or discomfort and have difficulty falling asleep.

How should this medicine be used?

Advil PM, which typically contains ibuprofen and diphenhydramine, should be used according to the following general guidelines:

• Dosage: Follow the dosage instructions provided on the product packaging or as directed by your healthcare provider. The dosage may vary depending on the specific formulation and strength of the medication.
• Administration: Advil PM is usually taken orally with water. It is important to swallow the tablets whole and not crush or chew them unless otherwise directed.
• Timing: It is typically recommended to take Advil PM before bedtime or as needed for pain relief. This is because diphenhydramine, one of the active ingredients, has sedative effects that can help with sleep.
• Duration: Use Advil PM for the shortest duration necessary to relieve your symptoms. Prolonged use may lead to dependence on the sleep-inducing effects of diphenhydramine.
• Avoid Alcohol: It is advisable to avoid consuming alcohol while taking Advil PM, as it can increase the risk of serious side effects such as stomach bleeding.
• Consultation: If you have any questions about how to use Advil PM, including concerns about dosage, potential interactions with other medications, or specific health conditions, consult your healthcare provider or pharmacist for guidance.

Always read and follow the package insert or label instructions carefully. If you experience any unusual symptoms or side effects while using Advil PM, seek medical attention promptly.

Other uses for this medicine

• Fever Reduction: Ibuprofen, one of the components of Advil PM, is effective in reducing fever. It can be used to lower elevated body temperature associated with various conditions.
• Allergy Relief: Diphenhydramine, the other component, is an antihistamine that can alleviate symptoms of allergies such as itching, sneezing, and runny nose.

What special precautions should I follow?

Special Precautions for Advil PM:

• Allergies: Inform your healthcare provider if you have any allergies to ibuprofen, diphenhydramine, or other medications. Allergic reactions to these substances can range from mild skin reactions to severe anaphylaxis.
• Medical Conditions: Advil PM should be used with caution or avoided altogether in certain medical conditions such as:
  • Stomach Ulcers or Bleeding: NSAIDs like ibuprofen can increase the risk of stomach bleeding or ulcers, especially with prolonged use or in individuals with a history of gastrointestinal issues.
  • Kidney or Liver Disease: These conditions can affect how your body processes medications like ibuprofen, potentially leading to complications.
  • Asthma: Some individuals with asthma may be more sensitive to NSAIDs and could experience exacerbations of their condition.
• Drug Interactions: Advil PM can interact with other medications, including blood thinners, certain antidepressants, and medications for high blood pressure. Always inform your healthcare provider about all medications (prescription and over-the-counter), supplements, and herbal products you are taking to avoid interactions.
• Pregnancy and Breastfeeding: Ibuprofen and diphenhydramine may not be safe during pregnancy, especially in the third trimester, and caution should be exercised while breastfeeding. Consult with your healthcare provider before using Advil PM if you are pregnant or nursing.
• Age Considerations: Advil PM is not typically recommended for children under 12 years old without specific medical advice due to the potential for serious side effects.
• Driving and Operating Machinery: Advil PM can cause drowsiness and impair your ability to perform tasks that require alertness. Avoid driving or operating machinery until you know how this medication affects you.

Always follow the dosing instructions provided on the package or by your healthcare provider. If you have any concerns or questions about using Advil PM, consult with a healthcare professional for personalized guidance based on your specific health needs and circumstances.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with Advil PM. However, it’s advisable to take it with food or milk to help reduce the risk of stomach upset, particularly if you have a history of gastrointestinal issues.

What should I do if I forget a dose?

• If you miss a dose of Advil PM, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Advil PM, which is a combination of ibuprofen (a pain reliever) and diphenhydramine (an antihistamine), can potentially cause several side effects. Here are some common ones:

• Drowsiness: Since diphenhydramine is an antihistamine with sedative effects, drowsiness is a common side effect. This is often why it’s used in products like Advil PM to aid sleep.
• Dry mouth: Antihistamines like diphenhydramine can reduce saliva production, leading to a dry mouth sensation.
• Dizziness: Some individuals may experience dizziness or lightheadedness, especially when getting up from a sitting or lying position.
• Blurred vision: Temporary blurred vision or difficulty focusing may occur, particularly at higher doses.
• Constipation or upset stomach: Ibuprofen can sometimes cause gastrointestinal irritation or constipation.
• Daytime drowsiness: If the medication is not fully metabolized by the time you wake up, you may feel drowsy or groggy in the morning.
• Cognitive effects: Some people may experience difficulty concentrating or confusion, especially in older adults.
• Allergic reactions: Though rare, some individuals may experience allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing.

It’s important to use Advil PM as directed and not exceed the recommended dosage. Long-term use or misuse can lead to more serious side effects, such as liver damage from ibuprofen or dependency on the sedative effects of diphenhydramine. Always consult with a healthcare provider if you have concerns about using Advil PM or experience any unusual symptoms.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage:
  • Store Advil PM at room temperature, away from moisture and heat.
  • Keep it out of reach of children and pets.
  • Avoid storing it in the bathroom where moisture could affect the medication.
• Disposal:
  • Dispose of Advil PM safely and responsibly to prevent accidental ingestion by children, pets, or others.
  • Follow any specific disposal instructions on the medication packaging or provided by your pharmacist.
  • If no specific instructions are provided, you can dispose of Advil PM by mixing it with an undesirable substance (like used coffee grounds or kitty litter) in a sealed plastic bag and throwing it in the trash. This helps prevent accidental ingestion by animals or people who may rummage through the trash.

In case of emergency/overdose

• Overdose Symptoms: Symptoms of ibuprofen overdose may include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, or coma. Symptoms of diphenhydramine overdose may include extreme drowsiness, confusion, hallucinations, fast or irregular heartbeat, flushed skin, or seizures.
• Action to Take: If you suspect an overdose of Advil PM, call your local poison control center at 1-800-222-1222 or seek emergency medical attention immediately. Be prepared to provide information about the amount ingested, when it was taken, and any symptoms experienced.

What other information should I know?

• Avoid Alcohol: Consumption of alcohol while taking Advil PM can increase the risk of serious side effects such as stomach bleeding.
• Driving and Activities: Advil PM can cause drowsiness and impair your ability to perform tasks that require alertness, such as driving or operating machinery. Avoid such activities until you know how this medication affects you.
• Medical Monitoring: Regularly monitor your health and report any new or worsening symptoms to your healthcare provider.
• Consultation: Before using Advil PM, discuss your medical history and all medications (including supplements and herbal products) with your healthcare provider to avoid potential interactions or complications.

Following these guidelines helps ensure safe and effective use of Advil PM. Always use medications as directed by your healthcare provider or as indicated on the product label, and seek medical attention promptly if you have concerns or experience adverse effects.