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AcipHex Sprinkles (Generic Rabeprazole)

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Why is this medication prescribed?

In adults and children 12 years of age and older, rabeprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which acid from the stomach flows backward, causing heartburn and possibly injuring the oesophagus (the tube that connects the throat and stomach). In adults, rabeprazole is used to treat GERD-related esophageal damage, promote esophageal healing, and stop further esophageal damage. Additionally, rabeprazole is used to treat diseases such adult Zollinger-Ellison syndrome, which are caused by excessive stomach acid production. In addition to being used in conjunction with other medications to treat ulcers (sores in the lining of the stomach or intestine), rabeprazole is also used to treat H. pylori, the bacteria that causes ulcers in adults. Proton-pump inhibitors are a class of drugs that includes rabeprazole. It functions by reducing the production of stomach acid.

How should this medicine be used?

The oral form of rabeprazole is a delayed-release tablet that delivers the medication in the intestine rather than the stomach, preventing stomach acids from breaking it down. Typically, one dose per day of the delayed-release tablets is required. Tablets of rabeprazole are administered after breakfast while treating ulcers. Rabeprazole tablets are given twice daily, with breakfast and dinner, for seven days as part of a treatment regimen that also includes additional medications to get rid of H. pylori. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take rabeprazole as prescribed by your doctor. Do not alter the dosage, frequency, or duration of use from what was recommended by your doctor.

Do not split, chew, or crush the pills; instead, swallow them whole with water.

Even if you feel good, keep taking rabeprazole. Without consulting your doctor, do not discontinue taking rabeprazole. Call your doctor if your condition doesn’t get better or worsens.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking rabeprazole,

  • If you have an allergy to rabeprazole, dexlansoprazole (Dexilant), esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, in Zegerid), pantoprazole (Protonix), any other drugs, or any of the ingredients in rabeprazole tablets, let your doctor and pharmacist know right once. Request a list of the components from your pharmacist.
  • If you are on rilpivirine, let your doctor know (Edurant, in Cabenuva, Complera, Juluca, Odefsey). If you are currently on this medicine, your doctor probably won’t advise you to use rabeprazole.
  • Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products that you are now taking or intend to use. Incorporate any of the following: Warfarin (Jantoven), atazanavir (Reyataz, in Evotaz), cyclosporine (Gengraf, Neoral, Sandimmune), dasatinib (Sprycel), digoxin (Lanoxin), and diuretics (‘water pills’) are examples of anticoagulants (‘blood thinners’), iron supplements, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept, Myfortic), nelfinavir (Viracept), nilotinib (Tasigna), itraconazole (Sporanox, Tolsura), ketoconazole, erlotinib (Tarceva), nilotinib (Tasigna), saquinavir (Astagra, Envarsus, Prograf). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Inform your doctor if you have or have ever had low levels of magnesium, calcium, or potassium in your blood; hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone [PTH], a natural substance needed to control the amount of calcium in the blood]); low levels of vitamin B12 in your body; osteoporosis (a condition in which the bones become thin and weak and break easily); or an autoimmune disease (condition in which the body attacks its own cells).
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor if you get pregnant while taking rabeprazole.
  • If you are 70 years of age or older, discuss the advantages and disadvantages of taking rabeprazole with your doctor. Never take this medication for a longer amount of time than your doctor has prescribed.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

There may be negative effects from rabeprazole. If any of these symptoms are severe or do not go away, consult your doctor:

  • Headache
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhea
  • Gas
  • Unwell throat

Some adverse effects can be very harmful. Get emergency medical assistance or call your doctor right away if you develop any of the following symptoms:

  • Skin that is bleeding, peeling, or blistered; lips, nose, mouth, or genital sores; enlarged glands; respiratory difficulty; fever; flu-like symptoms, etc.
  • Trouble breathing or swallowing; rash; hives; itching; swelling of the eyes, face, lips, mouth, throat, or tongue; or hoarseness.
  • Severe fatigue, a racing or pounding heartbeat, muscle spasms, involuntary trembling of a body part, lightheadedness, disorientation, or seizures
  • Severe stomach ache, persistent fever, watery stools, and diarrhoea
  • Joint ache that has recently appeared or is getting worse; a sun-sensitive rash on the arms or cheeks
  • Blood in the urine, frequent or infrequent urination, joint discomfort, weariness, nausea, or a loss of appetite

Other adverse effects of rabeprazole may occur. If you have any strange side effects while taking this medicine, contact your doctor right once.

Proton pump inhibitors like rabeprazole may increase the risk of fractures in the wrists, hips, or spine compared to those who do not take them. Proton pump inhibitor users run the risk of developing fundic gland polyps (a type of growth on the stomach lining). The hazards are greatest for those who take one of these medications in large doses or for a year or more. Consult your physician regarding the dangers of taking rabeprazole.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Store it away from excessive heat and moisture at room temperature (not in the bathroom).

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Prior to and throughout your therapy, your doctor might request specific laboratory testing.

Inform the lab staff and your doctor that you are taking rabeprazole prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • AcipHex®
  • AcipHex® Sprinkles
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