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Accretropin (Generic Somatropin)

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Why is this medication prescribed?

Somatropin injections are used to treat growth hormone insufficiency in both adults and children. Growth hormone is a natural hormone produced by your body. Children with specific diseases that hinder normal growth and development can potentially benefit from somatropin injections to accelerate their growth. In individuals with human immunodeficiency virus (HIV) who have HIV-associated wasting syndrome, somatropin injection (Serostim) is used to enhance body weight and physical endurance. Adults with short bowel syndrome who are receiving extra nourishment or fluids through intravenous (IV) therapy can be treated with somatropin injection (Zorbtive). An analogue of human growth hormone (hGH) is somatropin. It functions by supplementing the growth hormones the body normally produces, which may lead to greater weight, growth, and better nutritional and fluid absorption from the intestines.

How should this medicine be used?

In addition to being available as a powder in vials and cartridges to be combined with liquid and administered subcutaneously, somatropin injection is also available as a solution (liquid) in prefilled dosing pens and cartridges (under the skin). Adults often receive a somatropin injection once day to replenish growth hormone. Somatropin injections are often administered once day, three to seven days a week, to youngsters to replace growth hormone or promote growth. It is typical to administer somatropin injection (Serostim) once day or once every other day to patients with HIV-associated wasting syndrome in order to increase body weight and physical endurance. Short bowel syndrome is typically treated with somatropin injection (Zorbtive), which is typically administered once daily for 4 weeks. On each scheduled day, administer the somatropin injection at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you do not understand, and carefully follow their instructions. As recommended, administer somatropin injectable. Never use more or less of it or take it more frequently than your doctor has instructed.

You might begin taking somatropin at a low dose, then your doctor might gradually raise it.

Your doctor might prescribe your first dose of somatropin injections there, or he or she might let you or a caretaker administer the shots at home. You or the person administering the injections should read the manufacturer’s information for the patient included with the somatropin injection before using it for the first time. How to administer a dose of somatropin is explained in these directions. Make sure you comprehend these instructions. If you have any concerns regarding where or how to inject the medication, or about how to get rid of used needles and syringes after you inject the drug, see your healthcare professional.

Even if you feel well, keep using somatropin injectable. Without consulting your doctor, do not stop using somatropin injectable.

Before injecting somatropin, always check the solution. Verify that the liquid is clear and colourless and that the expiration date has not past. There shouldn’t be any observable particles in the liquid. If the product is expired or the liquid is hazy or includes particles, do not use it.

Syringes, needles, injection pens, and medicine bottles should never be shared or re-used. Used syringes, needles, injection pens, and vials should be disposed of in a receptacle that can withstand punctures and is out of children’s reach. How to get rid of the puncture-resistant container should be discussed with your doctor or pharmacist.

For a copy of the manufacturer’s information for the patient, ask your pharmacist or doctor.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using somatropin injection,

  • If you have an allergy to somatropin, any other drugs, benzyl alcohol, or any of the chemicals in somatropin injection, let your doctor and pharmacist know right away. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention any of the following: insulin and oral diabetes drugs; corticosteroids such as cortisone acetate, dexamethasone (Hemady), fludrocortisone, hydrocortisone (Alkindi Sprinkle, Cortef), and estrogen-containing medications (including birth control pills). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medications you are taking, even any not on this list, since many other drugs may also interact with somatropin.
  • Inform your doctor if you have recently undergone heart or stomach surgery, been in an accident or undergone trauma, have major breathing issues, or have sleep apnea, which causes you to stop breathing occasionally while you sleep, cancer, or diabetic retinopathy (damage to the eyes caused by diabetes). Your physician could advise against using somatropin injectable.
  • If you have diabetes, let your physician know or have previously had diabetes, as well as if you have ever undergone radiation therapy to the head or brain. pancreatitis (pancreatic swelling); adrenal insufficiency (condition in which the adrenal glands can not produce enough of specific hormones required for vital physiological functions); scoliosis, excessive blood phosphate levels, thyroid, parathyroid, or liver issues, as well as papilledema (swelling of the optic nerve brought on by increased pressure in the brain), can all create a curve in the spine. Children whose growth plates have closed and whose bones are no longer expanding shouldn’t use somatropin (usually after puberty).
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking somatropin injectable.
  • Inform the surgeon or dentist that you are using somatropin injection if you are having surgery, including dental surgery.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What should I do if I forget a dose?

If you overlook an injection of this drug, call your doctor. When you should administer the missing dose and the subsequent scheduled dose, your doctor will instruct you. To make up for a missing dose, do not provide a second injection.

What side effects can this medication cause?

Side effects from somatropin could exist. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Skin thickening at the site of an injection
  • Pain, erythema, edoema, or itching at the injection site
  • Headache
  • Joint or muscle ache
  • Fever, cough, sore throat, or other infection-related symptoms
  • An earache
  • Large volumes of gas or flatulence in the intestines or guts
  • Hair fall

Some adverse effects can be very harmful. Stop taking the medication and contact your doctor right away if you develop any of these symptoms, or seek emergency medical attention:

  • Headaches, nausea, vomiting, and vsion changes
  • Hives, rash, itching, sweating, swelling of the eyes, face, lips, tongue, or throat, hoarseness, lightheadedness, fainting, or chest pain are just a few symptoms that might occur.
  • Nausea, vomiting, or a persistent loss of appetite that starts in the back but may also radiate from the stomach
  • Hands, fingers, arms, legs, or feet that are numb, burning, tingly, or tingly
  • Hands, foot, ankles, or lower legs swelling
  • Excessive fatigue, pain in the muscles or joints, weakness, dizziness, skin discoloration, or loss of weight
  • Limping, recent or ongoing knee or hip discomfort
  • Snoring, breathing issues, or sleep apnea
  • Bigger breasts

The chance of acquiring certain cancers, such as brain or skin cancer, may rise as a result of somatropin use. Immediately contact your physician if you experience any of the following signs: headaches, changes in moles, birthmarks, or skin tone, as well as changes in behaviour or vision.

Other negative effects of somatropin are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

The best way to preserve your medication will be advised by your doctor. Just as prescribed, only store your prescription. Be sure to know the right way to store your medications.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Symptoms of overdose may include:

  • Hands, foot, ankles, or lower legs swelling
  • Sweating excessively and bad body odour
  • Enlarged tongue, lips, nose, hands, and feet
  • Weakened muscles or joints

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor your body’s reaction to somatropin, your doctor could request specific lab tests.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Accretropin®
  • Genotropin ®
  • Humatrope®
  • Norditropin®
  • Nutropin®
  • Nutropin® AQ® Nuspin®
  • Omnitrope®
  • Saizen®
  • Serostim®
  • Zomacton
  • Zorbtiv
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