WARNING

As with any medical treatment, there are risks associated with its use. Some potential risks of DaxibotulinumtoxinA-lanm injection include:

• Injection site reactions: This can include pain, swelling, bruising, or redness at the injection site. These reactions are usually temporary but can be bothersome for some individuals.
• Muscle weakness or paralysis: Since DaxibotulinumtoxinA-lanm injection works by temporarily paralyzing muscles, there’s a risk of unintended muscle weakness or paralysis. This can lead to drooping eyelids or eyebrows if the toxin spreads beyond the intended area.
• Allergic reactions: Although rare, some people may be allergic to DaxibotulinumtoxinA-lanm injection or the components used in the injection, leading to allergic reactions ranging from mild irritation to severe allergic responses.
• Eyelid or eyebrow drooping: Improper injection technique or diffusion of the toxin beyond the targeted area can result in temporary drooping of the eyelids or eyebrows, affecting vision or facial appearance.
• Headaches or other side effects: Some individuals may experience headaches or other side effects after DaxibotulinumtoxinA-lanm injection injections. These side effects are usually mild and temporary but can vary depending on individual sensitivity.
• Spread of toxin: There’s a risk that the toxin can spread beyond the injection site, affecting nearby muscles and causing unintended side effects.

It’s essential to discuss these risks with a qualified healthcare provider before undergoing DaxibotulinumtoxinA-lanm injection injections, ensuring that the treatment is appropriate for your individual circumstances and medical history.

Why is this medication prescribed?

DaxibotulinumtoxinA-lanm injection is used to temporarily smooth frown lines (wrinkles between the eyebrows) in adults 18 years of age and older. It is a type of botulinum toxin that works by temporarily paralyzing the muscles responsible for creating wrinkles, thereby smoothing out the skin’s appearance.

How should this medicine be used?

DaxibotulinumtoxinA-lanm injection comes as a powder to be mixed with a liquid and injected into a muscle by a healthcare provider. Your healthcare provider may adjust the dose until they find the best dose for you. DaxibotulinumtoxinA-lanm injection should not be administered more frequently than every 3 months.

The dosing and frequency of DaxibotulinumtoxinA-lanm injection depend on various factors, including the severity of the wrinkles, the individual’s facial anatomy, and their treatment goals. Typically, the effects of DaxibotulinumtoxinA-lanm injection last for several months before gradually wearing off, necessitating repeat treatments to maintain the desired results.

It’s essential to follow the healthcare provider’s instructions carefully regarding the preparation, administration, and aftercare of DaxibotulinumtoxinA-lanm injection to ensure optimal results and minimize the risk of complications. Additionally, individuals receiving DaxibotulinumtoxinA-lanm injection should discuss any concerns or medical conditions with their healthcare provider before undergoing treatment.

Other uses for this medicine

• Daurismo is primarily indicated for the treatment of newly diagnosed AML in combination with low-dose cytarabine.
• It’s important to note that Daurismo is not approved for use in children.

What special precautions should I follow?

Regarding special precautions for DaxibotulinumtoxinA-lanm injection treatment, it’s essential to follow the guidance of a qualified healthcare provider. Here are some general precautions to consider:

• Medical history: Inform your healthcare provider about any medical conditions you have, especially nerve or muscle disorders, allergies, or previous reactions to botulinum toxin injections.
• Medications: Disclose all medications, supplements, and herbal remedies you are taking, as some may interact with DaxibotulinumtoxinA-lanm injection or increase the risk of side effects.
• Pregnancy and breastfeeding: DaxibotulinumtoxinA-lanm injection are not recommended during pregnancy or breastfeeding, as the effects on the fetus or nursing infant are not well studied.
• Avoid alcohol: Avoid consuming alcohol before and after DaxibotulinumtoxinA-lanm injection, as it may increase the risk of bruising at the injection sites.
• Follow-up appointments: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to treatment and address any concerns or side effects promptly.

By following these precautions and working closely with your healthcare provider, you can maximize the safety and effectiveness of DaxibotulinumtoxinA-lanm treatment for your specific needs.

What special dietary instructions should I follow?

Regarding forgetting a dose, DaxibotulinumtoxinA-lanm injection is typically administered as a one-time injection during each treatment session. If you miss a scheduled appointment for DAXI injections, it’s essential to reschedule as soon as possible to maintain the desired results. However, since DaxibotulinumtoxinA-lanm injection is not a medication that you take on a regular schedule like a pill, the concept of forgetting a dose doesn’t apply in the same way as it does for oral medications.

What should I do if I forget a dose?

If you have any concerns about your DaxibotulinumtoxinA-lanm treatment, including missed appointments or questions about dietary considerations, it’s best to discuss them with your healthcare provider. They can provide personalized guidance based on your specific situation and treatment plan.

What side effects can this medication cause?

DaxibotulinumtoxinA (DAXI) injections, like any medical procedure, can potentially cause side effects. Common side effects associated with DaxibotulinumtoxinA-lanm treatment may include:

• Injection site reactions: These can include pain, swelling, bruising, redness, or itching at the injection site. These reactions are usually mild and temporary.
• Muscle weakness or drooping: DaxibotulinumtoxinA-lanm injection works by temporarily paralyzing muscles, which can sometimes lead to temporary weakness or drooping of nearby muscles. For example, drooping of the eyelids (ptosis) or eyebrows may occur if the toxin spreads beyond the intended treatment area.
• Headache: Some individuals may experience headaches after DaxibotulinumtoxinA-lanm injection. These headaches are typically mild and short-lived.
• Flu-like symptoms: In some cases, individuals may experience symptoms such as fatigue, muscle weakness, or flu-like symptoms after DaxibotulinumtoxinA-lanm injection. These symptoms are usually temporary and resolve on their own.
• Dry eyes or excessive tearing: DaxibotulinumtoxinA-lanm injection near the eyes can sometimes affect tear production, leading to symptoms of dry eyes or excessive tearing.
• Allergic reactions: Although rare, allergic reactions to DaxibotulinumtoxinA-lanm injection or its components can occur. Symptoms of an allergic reaction may include itching, rash, hives, swelling, difficulty breathing, or dizziness. Seek medical attention immediately if you experience any signs of an allergic reaction.
• Other rare side effects: Rarely, DaxibotulinumtoxinA-lanm injection may cause more severe side effects, such as difficulty swallowing, speaking, or breathing, or other serious adverse events. These are uncommon but require immediate medical attention if they occur.

It’s essential to discuss the potential side effects of DaxibotulinumtoxinA-lanm treatment with your healthcare provider before undergoing the procedure. They can provide personalized guidance based on your medical history and individual risk factors. Additionally, if you experience any concerning or persistent side effects after DaxibotulinumtoxinA-lanm injection, contact your healthcare provider for further evaluation and management.

What should I know about storage and disposal of this medication?

Storage and disposal of DaxibotulinumtoxinA (DAXI) are important considerations to ensure safety and efficacy:

• Storage: DaxibotulinumtoxinA-lanm injection should be stored in a refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). It should be kept in its original packaging to protect it from light and moisture. Do not freeze DaxibotulinumtoxinA-lanm injection, as freezing can damage the product. Keep it out of reach of children and pets.
• Disposal: Unused or expired DaxibotulinumtoxinA-lanm injection should be disposed of properly according to local regulations for the disposal of medical waste. Do not dispose of DaxibotulinumtoxinA-lanm injection in household trash unless instructed to do so by your healthcare provider or pharmacist. Contact your healthcare provider or local waste management authorities for guidance on proper disposal procedures.

In case of emergency/overdose

In case of emergency or overdose of DaxibotulinumtoxinA-lanm injection, immediate medical attention is necessary. Symptoms of overdose or adverse reactions may include severe muscle weakness, difficulty breathing or swallowing, speech difficulties, or other serious symptoms. If you or someone else may have overdosed on DaxibotulinumtoxinA-lanm injection, contact emergency services (such as 911 in the United States) or seek medical assistance immediately.

What other information should I know?

• Follow-up appointments: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to treatment and address any concerns or side effects promptly.
• Avoid rubbing or massaging: Avoid rubbing or massaging the treated area immediately after DaxibotulinumtoxinA-lanm injection, as this can cause the toxin to spread to unintended areas and increase the risk of side effects.
• Limit sun exposure: After DaxibotulinumtoxinA-lanm treatment, it’s advisable to limit sun exposure and use sunscreen to protect your skin, as sun exposure can accelerate the breakdown of DaxibotulinumtoxinA-lanm injection and reduce its effectiveness.
• Inform healthcare providers: Inform all healthcare providers involved in your care that you have received DaxibotulinumtoxinA-lanm injection, especially if you are undergoing any other medical treatments or procedures.
• Report side effects: If you experience any side effects or adverse reactions after DaxibotulinumtoxinA-lanm treatment, report them to your healthcare provider or pharmacist. They can provide guidance on managing side effects and may need to report them to the appropriate regulatory authorities.

By following these guidelines and staying informed about DaxibotulinumtoxinA-lanm treatment, you can help ensure safe and effective results.