Why is this medication prescribed?

Amerge (generic naratriptan) is prescribed to treat migraine headaches. It belongs to a class of medications called triptans, which work by constricting blood vessels in the brain and reducing inflammation, thereby alleviating migraine symptoms. Naratriptan is typically used when other treatments are not effective or suitable.

• Constriction of Blood Vessels: It helps to narrow dilated blood vessels in the brain, which can reduce the intensity of a migraine.
• Reducing Inflammation: It decreases inflammation and the release of certain chemicals in the brain that contribute to migraine symptoms.
• Relieving Symptoms: It helps alleviate common migraine symptoms such as severe headache, nausea, and sensitivity to light and sound.

Amerge is not used to prevent migraines but rather to relieve the symptoms once a migraine has started.

How should this medicine be used?

Here are some general guidelines:

• Dosage: Amerge is usually taken as a single oral tablet. The typical dose is 1 mg or 2.5 mg, depending on the severity of the migraine and individual response. If your symptoms return or don’t improve after the first dose, your healthcare provider may prescribe a second dose, but you should wait at least 4 hours between doses.
• Administration: Take the tablet by mouth with or without food. It’s important to follow your healthcare provider’s instructions on how often to take the medication.
• Avoid Overuse: Don’t use Amerge for more than 4 headaches in a month. Overuse can lead to rebound headaches or other complications.
• Check for Interactions: Be aware of potential interactions with other medications. Inform your healthcare provider about all the medications and supplements you’re taking.
• Not for Daily Use: Amerge is not intended for daily use or for the prevention of migraines. It’s specifically for treating migraine attacks once they start.

If you have any concerns or experience side effects, consult your healthcare provider for further guidance.

Other uses for this medicine

• Acute Migraine Treatment Only: Amerge is specifically indicated for treating acute migraine attacks and is not used for conditions other than migraines.

What special precautions should I follow?

Special Precautions:

• Medical History: Inform your healthcare provider if you have a history of cardiovascular disease, high blood pressure, liver disease, or kidney disease. These conditions may affect the safety and efficacy of Amerge.
• Medication Interactions: Be cautious if you are taking other medications, especially other triptans, ergotamines, or medications that affect serotonin levels (e.g., certain antidepressants). Combining these can increase the risk of serotonin syndrome or other adverse effects.
• Heart Risk: If you experience chest pain, tightness, or other symptoms of a heart attack, seek medical attention immediately. Though rare, triptans can cause cardiovascular side effects.
• Allergic Reactions: If you experience signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, or trouble breathing), discontinue use and contact your healthcare provider.
• Frequency of Use: Avoid using Amerge more frequently than prescribed. Overuse can lead to rebound headaches or increased migraine frequency.
• Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding, as the safety of Amerge in these situations hasn’t been fully established.
• Dosage: Follow your healthcare provider’s instructions regarding dosage. Do not exceed the recommended dose or take more frequent doses than prescribed.

Always discuss any concerns or questions with your healthcare provider to ensure that Amerge is used safely and effectively for your specific situation.

What special dietary instructions should I follow?

There are no specific dietary restrictions or requirements associated with Amerge. However, maintaining a healthy diet and staying hydrated may help in managing migraine symptoms and overall health. If you have specific dietary concerns or conditions that might affect your treatment, discuss them with your healthcare provider.

What should I do if I forget a dose?

Amerge is typically taken as needed for acute migraine attacks, so missing a dose generally means you should wait until the next migraine occurs or as directed by your healthcare provider. If you have specific instructions about dosing frequency or additional doses, follow those guidelines. Do not take a double dose to make up for a missed dose. If you have any questions or are unsure about what to do, consult your healthcare provider.

What side effects can this medication cause?

Amerge (Naratriptan) can cause a range of side effects, though not everyone will experience them. Common side effects include:

• Dizziness or Lightheadedness: Some people may feel dizzy or lightheaded after taking Amerge.
• Fatigue: Tiredness or drowsiness can occur.
• Nausea: A feeling of nausea may be experienced by some individuals.
• Dry Mouth: Some users report dry mouth as a side effect.
• Flushing: Warmth or redness in the skin, particularly in the face, may occur.

Less common but more serious side effects include:

• Chest Pain or Pressure: If you experience chest pain or tightness, seek immediate medical attention as this could be a sign of a serious cardiovascular issue.
• Shortness of Breath: Difficulty breathing or a sensation of breathlessness can be a serious symptom.
• Severe Allergic Reactions: Symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing can indicate an allergic reaction.
• Serotonin Syndrome: Symptoms like agitation, hallucination, fever, excessive sweating, rapid heartbeat, muscle spasm, or tremors might indicate serotonin syndrome, a rare but serious condition.
• High Blood Pressure: Amerge can cause an increase in blood pressure in some individuals.

If you experience any of these serious side effects or have concerns about the medication, contact your healthcare provider immediately. They can help determine whether Amerge is appropriate for you or if adjustments need to be made.

What should I know about storage and disposal of this medication?

Storage and Disposal of Amerge:

• Storage:
  • Store Amerge at room temperature, away from excessive heat and moisture. Typically, this means keeping it at temperatures between 59°F and 77°F (15°C to 25°C).
  • Keep the medication in its original container, tightly closed, and out of reach of children.
• Disposal:
  • Do not flush Amerge down the toilet or pour it into a drain unless instructed to do so by a drug take-back program or your pharmacist.
  • Use a drug take-back program or follow local disposal guidelines for the safe disposal of unused or expired medication. Many pharmacies and community programs offer safe disposal options.
  • If no take-back programs are available, you may dispose of Amerge in the household trash by mixing it with an undesirable substance (like used coffee grounds or cat litter) in a sealed plastic bag to prevent leakage.

In case of emergency/overdose

• Overdose Symptoms: Symptoms of an overdose may include severe dizziness, drowsiness, and a significant increase in blood pressure.
• Seek Medical Attention: If you suspect an overdose or experience severe symptoms, contact emergency medical services or go to the nearest emergency room immediately.
• Provide Information: Be prepared to provide information about the medication, the amount taken, and the time of ingestion.

What other information should I know?

• Regular Monitoring: Regular follow-ups with your healthcare provider may be necessary to monitor the effectiveness of the medication and any potential side effects.
• Record Keeping: Keep a record of your migraine occurrences and medication use to help your healthcare provider assess the treatment’s effectiveness.
• Inform Healthcare Providers: Always inform any new healthcare provider or pharmacist about all the medications you are currently taking, including Amerge.
• Medication Interactions: Be cautious of potential interactions with other medications, including over-the-counter drugs and supplements.

If you have any additional questions or concerns about Amerge, consult your healthcare provider or pharmacist for personalized advice and guidance.