WARNING

Aliqopa (generic name Copanlisib) is used to treat certain types of lymphoma. Its risks include:

• Infections: It can weaken the immune system, increasing the risk of infections.
• Blood Clotting Issues: It may cause problems with blood clotting, leading to bleeding or thrombosis.
• Liver Problems: Liver function can be affected, potentially causing liver damage.
• High Blood Sugar: It might increase blood sugar levels, which can be problematic for people with diabetes or those at risk.
• Gastrointestinal Issues: Nausea, diarrhea, and other digestive problems are possible.
• Fatigue: Common side effects include feeling tired or weak.

Patients should be monitored regularly while on Aliqopa to manage these risks. Always consult a healthcare provider for personalized advice and monitoring.

Why is this medication prescribed?

Aliqopa (Copanlisib) is prescribed primarily for the treatment of certain types of non-Hodgkin lymphoma, such as follicular lymphoma, particularly in cases where the disease has relapsed or is resistant to other treatments.

How should this medicine be used?

Here’s a general overview of how it is used:

• Administration: It is given as an intravenous (IV) infusion, usually in a healthcare setting.
• Dosage Schedule: Typically, it is administered every 3 weeks for a specified number of cycles, depending on the patient’s response and tolerance.
• Preparation: The drug must be prepared and administered by a trained healthcare professional to ensure correct dosage and to manage any potential side effects.
• Monitoring: Regular blood tests and monitoring are required to check for side effects and to assess the effectiveness of the treatment.

Always follow the specific instructions provided by your healthcare provider regarding the use of Aliqopa, as they will tailor the treatment to your individual needs.

Other uses for this medicine

While Aliqopa (Copanlisib) is primarily prescribed for treating certain types of non-Hodgkin lymphoma, research and clinical trials may explore its efficacy in other types of cancer or conditions. However, its use outside its approved indications should be guided by a healthcare provider.

What special precautions should I follow?

Special Precautions:

• Infections: Due to its effect on the immune system, it’s crucial to watch for signs of infection and to report any symptoms such as fever or chills to your healthcare provider.
• Liver Function: Regular liver function tests are necessary because Aliqopa can cause liver damage. Report any symptoms of liver issues, such as jaundice (yellowing of the skin or eyes) or dark urine.
• Blood Sugar Levels: Monitor blood sugar levels closely if you have diabetes or are at risk of high blood sugar, as Aliqopa can elevate blood glucose.
• Blood Clotting: Be aware of any unusual bleeding or bruising, and inform your doctor if you experience these symptoms. Regular blood tests may be needed to monitor clotting.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your healthcare provider, as Aliqopa may have harmful effects on the fetus or infant.
• Drug Interactions: Inform your doctor about all other medications and supplements you are taking to avoid potential interactions.
• Heart Health: If you have a history of heart problems, let your healthcare provider know, as Aliqopa may affect heart function.

Always follow your healthcare provider’s guidance and attend all scheduled appointments for monitoring and management of side effects.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Aliqopa. However, maintaining a balanced diet can help manage side effects and support overall health. If you experience gastrointestinal symptoms such as nausea or diarrhea, consider eating small, frequent meals and staying hydrated.

What should I do if I forget a dose?

• Contact Your Healthcare Provider: If you miss a dose, contact your healthcare provider or treatment center for advice on what to do next. They can provide guidance on whether to take the missed dose or to wait until the next scheduled dose.
• Do Not Double Up: Do not take a double dose to make up for a missed dose unless directed by your healthcare provider.
• Follow the Schedule: Try to keep a record of your doses to prevent missing any in the future.

What side effects can this medication cause?

Aliqopa (Copanlisib) can cause a range of side effects, some of which may be serious. Common side effects include:

• Infections: Increased risk of infections due to immune system suppression.
• Gastrointestinal Issues: Nausea, diarrhea, vomiting, and loss of appetite.
• Fatigue: Feeling tired or weak.
• Elevated Blood Sugar: Increased blood glucose levels, which can be problematic for people with diabetes.
• Liver Problems: Changes in liver function, potentially causing jaundice or other liver-related symptoms.
• Blood Clotting Issues: Bleeding or bruising due to effects on blood clotting.
• Abdominal Pain: Pain or discomfort in the abdominal area.
• Rashes: Skin rashes or itching.

Less common but potentially serious side effects include:

• Severe Infections: More severe or systemic infections.
• Liver Damage: Significant liver dysfunction requiring medical attention.
• Heart Issues: Potential impact on heart function.

It’s important to report any new or worsening symptoms to your healthcare provider, as they can help manage side effects and adjust treatment as needed. Regular monitoring and follow-up appointments are crucial to ensure any side effects are addressed promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aliqopa:

• Storage:
  • Aliqopa is typically administered in a healthcare setting, so it is usually stored and handled by medical professionals.
  • Follow specific storage instructions provided by your healthcare provider or the product’s manufacturer. Aliqopa should be stored according to the guidelines for temperature and conditions to ensure its effectiveness.
• Disposal:
  • Disposal should be handled by healthcare professionals to avoid contamination or improper handling.
  • Do not dispose of Aliqopa in household trash or flush it down the toilet. Follow your healthcare provider’s instructions or contact a local pharmacy or waste disposal service for proper disposal methods.

In case of emergency/overdose

• Seek Immediate Help: If you suspect a serious reaction or emergency related to Aliqopa, contact emergency services or go to the nearest emergency room.
• Symptoms: Report symptoms such as severe allergic reactions, significant bleeding, or signs of liver damage.
• Contact a Healthcare Professional: If you or someone else may have received an overdose, contact your healthcare provider or poison control center immediately.
• Symptoms: Be aware of symptoms such as severe gastrointestinal issues, unusual bleeding, or signs of liver problems.

What other information should I know?

• Regular Monitoring: Regular follow-ups and monitoring are essential to manage side effects and adjust treatment as needed. Attend all scheduled appointments and report any new symptoms promptly.
• Inform Healthcare Providers: Always inform your healthcare provider of any other medications, supplements, or medical conditions you have to avoid interactions and ensure appropriate care.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider to understand the risks and ensure safe management.
• Adherence: Follow your healthcare provider’s instructions carefully regarding the dosage and administration of Aliqopa to ensure optimal effectiveness and minimize side effects.

Always keep an open line of communication with your healthcare provider to address any concerns or questions regarding your treatment with Aliqopa.