WARNING

Aleve (generic name naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce inflammation, and lower fever. Like all medications, it comes with potential risks and side effects. Here are some detailed risks associated with taking Aleve:

• Stomach Pain and Nausea: Common side effects include stomach pain, indigestion, and nausea.
• Ulcers and Bleeding: Long-term use or high doses can lead to stomach ulcers or gastrointestinal bleeding, which may be serious. Symptoms to watch for include black or tarry stools, vomiting blood, or severe stomach pain.
• Heart Attack and Stroke: Prolonged use of NSAIDs like naproxen can increase the risk of heart attack and stroke, especially at high doses or in individuals with existing heart conditions.
• High Blood Pressure: Naproxen can cause or worsen high blood pressure.
• Kidney Damage: Long-term use can affect kidney function, leading to potential kidney damage. Symptoms may include swelling in the legs, ankles, or feet, and changes in urine output.
• Liver Damage: Though rare, naproxen can cause liver problems. Symptoms include jaundice (yellowing of the skin or eyes), dark urine, and severe fatigue.
• Rashes and Swelling: Some people may experience allergic reactions, which can include rash, itching, or swelling. Severe reactions like anaphylaxis are rare but require immediate medical attention.
• Asthma Exacerbation: Naproxen may worsen asthma in some people.
• Blood Thinners: Naproxen can interact with blood thinners, increasing the risk of bleeding.
• Other NSAIDs: Using multiple NSAIDs simultaneously can increase the risk of adverse effects.
• Pregnancy: Naproxen is generally not recommended during the third trimester of pregnancy due to potential risks to the fetus and complications during delivery.
• Breastfeeding: Naproxen passes into breast milk, so consult a healthcare provider if breastfeeding.
• Pre-existing Conditions: Individuals with certain pre-existing conditions (e.g., peptic ulcer disease, severe heart disease, liver disease) should use naproxen with caution and under medical supervision.

Always use Aleve or any NSAID according to your healthcare provider’s directions and inform them of any other medications you are taking or health conditions you have. If you experience any severe or unusual symptoms while taking Aleve, seek medical attention immediately.

Why is this medication prescribed?

Aleve, which is the brand name for naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for the following reasons:

• Pain Relief: It is used to relieve mild to moderate pain from various conditions such as headaches, muscle aches, tendonitis, dental pain, and menstrual cramps.
• Inflammation Reduction: Naproxen is effective in reducing inflammation and is often used to treat conditions like arthritis, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout.
• Fever Reduction: It can also be used to reduce fever.
• Chronic Conditions: For some chronic conditions like arthritis, naproxen may be prescribed for long-term use to manage persistent pain and inflammation.
• Injury Management: It is also used for pain and swelling due to injuries such as sprains and strains.

Naproxen works by blocking the production of certain natural substances in your body that cause inflammation, which helps to reduce pain and swelling. However, it should be used under medical guidance, as prolonged use or high doses can lead to potential side effects such as gastrointestinal issues, cardiovascular risks, or kidney problems.

How should this medicine be used?

Aleve (generic naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. Here are some general guidelines for its use:

• Dosage: Typically, the recommended dose for pain is 220 mg to 440 mg every 8 to 12 hours as needed. The maximum daily dose is usually 660 mg. The dosage for children should be determined by a healthcare provider.
• Administration: Take Aleve with a full glass of water to help prevent stomach irritation. It can be taken with food or milk to minimize stomach upset.
• Duration: Use the lowest effective dose for the shortest duration necessary to relieve your symptoms.
• Precautions: Avoid using Aleve if you have a history of stomach ulcers, gastrointestinal bleeding, or severe kidney or liver issues without consulting a healthcare provider. It may interact with other medications, so inform your healthcare provider of all the medications you’re taking. Avoid alcohol as it may increase the risk of stomach bleeding.
• Consult a Healthcare Provider: If you have any chronic conditions, are pregnant or breastfeeding, or if symptoms persist or worsen, consult your healthcare provider before use.

Always follow the instructions on the packaging or provided by your healthcare provider.

Other uses for this medicine

Aleve (naproxen) is primarily used for:

• Pain Relief: Managing mild to moderate pain from conditions like headaches, toothaches, menstrual cramps, or muscle aches.
• Anti-inflammatory: Reducing inflammation and pain associated with conditions like arthritis, including osteoarthritis and rheumatoid arthritis.
• Fever Reduction: Lowering fever associated with various conditions.

What special precautions should I follow?

Special Precautions:

• Allergies: Inform your healthcare provider if you have any allergies, especially to NSAIDs (nonsteroidal anti-inflammatory drugs) or other medications.
• Gastrointestinal Issues: If you have a history of stomach ulcers, gastrointestinal bleeding, or other stomach issues, use Aleve with caution as it can increase the risk of these problems.
• Heart Disease: If you have a history of heart disease, high blood pressure, or stroke, discuss with your doctor before using Aleve, as long-term use can increase cardiovascular risk.
• Kidney Function: Those with kidney problems should be cautious, as Aleve can affect kidney function. Regular monitoring may be necessary.
• Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding, as Aleve may not be recommended during pregnancy or breastfeeding.
• Other Medications: Inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid interactions.
• Alcohol: Limit alcohol intake while taking Aleve, as it can increase the risk of stomach bleeding.
• Dosage: Follow the recommended dosage and avoid taking more than directed. Long-term use should be monitored by a healthcare provider.

If you have any specific conditions or concerns, it’s always best to consult with a healthcare professional for personalized advice.

What special dietary instructions should I follow?

• General Diet: There are no specific dietary restrictions while taking naproxen, but to minimize stomach upset, you might want to take it with food or milk.
• Hydration: Ensure you stay well-hydrated, especially if taking naproxen over an extended period, as it can affect kidney function.
• Avoiding Certain Foods: While there are no strict food restrictions, reducing the intake of alcohol and avoiding excessive caffeine might help minimize the risk of stomach irritation.

What should I do if I forget a dose?

• If Taken as Needed: If you’re taking naproxen on an as-needed basis (e.g., for pain relief), you don’t need to worry about missing a dose. Simply take the next dose when needed.
• If on a Regular Schedule: If you’re taking naproxen on a regular schedule (e.g., for chronic conditions like arthritis) and miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose—do not take a double dose to make up for the missed one.

What side effects can this medication cause?

Aleve (naproxen) can cause a range of side effects, some of which may require medical attention. Here’s a breakdown of potential side effects:

Common Side Effects: These are usually mild and may go away as your body adjusts to the medication:

• Stomach pain or discomfort
• Heartburn
• Nausea
• Dizziness
• Headache
• Drowsiness
• Constipation
• Rash
• Ringing in the ears (tinnitus)

Serious Side Effects: These are less common but can be serious. If you experience any of these, you should seek medical attention immediately:

• Gastrointestinal Issues:
  • Severe stomach or abdominal pain
  • Black or tarry stools (a sign of bleeding)
  • Vomiting blood or material that looks like coffee grounds
  • Persistent indigestion or nausea
• Cardiovascular Issues:
  • Chest pain
  • Shortness of breath
  • Weakness on one side of the body
  • Slurred speech
• Kidney Issues:
  • Changes in the amount of urine
  • Swelling of the hands, feet, or ankles (edema)
  • Unusual weight gain
• Liver Issues:
  • Yellowing of the skin or eyes (jaundice)
  • Dark urine
  • Severe fatigue
  • Persistent nausea or vomiting
• Allergic Reactions:
  • Rash, itching, or swelling (especially of the face, tongue, or throat)
  • Severe dizziness
  • Difficulty breathing
• Blood Disorders:
  • Easy bruising or bleeding
  • Unusual fatigue
  • Signs of infection (such as fever, chills, or persistent sore throat)

If mild side effects persist or become bothersome, consult your healthcare provider. If you experience any serious side effects, stop taking the medication and seek immediate medical attention. It’s important to use Aleve (naproxen) as directed by your healthcare provider and to discuss any concerns or side effects with them. They may adjust your dose or suggest an alternative treatment if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Aleve (Naproxen):

Storage:

• Keep Aleve at Room Temperature: Store it in a cool, dry place away from light and moisture.
• Keep Out of Reach of Children: Ensure it is stored in a location that children cannot access to prevent accidental ingestion.

Disposal:

• Follow Local Guidelines: Dispose of Aleve according to local regulations or take it to a drug take-back program.
• Avoid Flushing: Do not flush Aleve down the toilet or pour it into a drain unless instructed to do so by your pharmacist or local waste disposal authority.

In case of emergency/overdose

• Seek Immediate Medical Help: If you suspect an overdose or experience severe symptoms (e.g., nausea, vomiting, stomach pain, drowsiness, or difficulty breathing), contact emergency services or go to the nearest emergency room immediately.
• Contact Poison Control: You can also call the Poison Control Center for guidance. The number for the U.S. Poison Control Center is 1-800-222-1222.

What other information should I know?

• Dosage: Follow the dosage instructions on the label or prescribed by your healthcare provider. Do not exceed the recommended dose.
• Interactions: Be aware of potential interactions with other medications or health conditions. Inform your healthcare provider about all the medications you are taking.
• Side Effects: Common side effects may include stomach upset, headache, or dizziness. If you experience severe side effects like gastrointestinal bleeding, severe allergic reactions, or liver issues, seek medical attention immediately.

If you have any specific concerns or conditions, consulting with a healthcare professional is always a good idea.