Why is this medication prescribed?

Ciloprost is a medication primarily prescribed for the treatment of pulmonary arterial hypertension (PAH). PAH is a condition characterized by high blood pressure in the arteries of the lungs, leading to shortness of breath, dizziness, and eventually heart failure if untreated. Ciloprost works by dilating (widening) the blood vessels in the lungs, which helps to lower blood pressure and reduce the workload on the heart.

How should this medicine be used?

Ciloprost is typically administered via inhalation. Here are the general guidelines for its use:

• Administration: Ciloprost is usually inhaled through a special device called a nebulizer. The nebulizer turns the medication into a fine mist that you breathe in through a face mask or mouthpiece.
• Dosage: The dosage and frequency of Ciloprost inhalation will be prescribed by your healthcare provider based on your specific condition and response to treatment.
• Timing: It is usually taken multiple times per day, with specific intervals between doses as directed by your doctor.
• Consistency: It is important to use Ciloprost exactly as prescribed by your healthcare provider. Do not change your dose or stop using this medication without first consulting your doctor.
• Monitoring: Your doctor may periodically adjust your dose to achieve the best results with the fewest side effects.
• Storage: Store Ciloprost ampules (the containers with the medication) in the refrigerator until you are ready to use them. Once opened, use the medication right away.
• Usage Instructions: Follow the instructions provided with your medication for proper use of the nebulizer and inhalation technique.

As with any medication, it’s important to discuss any concerns or questions you have with your healthcare provider. They can provide specific guidance tailored to your individual needs and health condition.

Other uses for this medicine

While it is primarily used for PAH, sometimes Iloprost might be considered off-label for other conditions where pulmonary vasodilation is beneficial, but this should only be under the guidance of a healthcare provider.

What special precautions should I follow?

Special Precautions for Ciloprost (Iloprost):

• Allergies: Inform your healthcare provider if you have any allergies to iloprost or any other medications.
• Medical Conditions: Before starting iloprost, disclose your medical history, especially of any heart conditions, kidney disease, liver disease, or bleeding disorders.
• Pregnancy and Breastfeeding: It is important to discuss the risks and benefits of using iloprost if you are pregnant, planning to become pregnant, or breastfeeding.
• Interactions: Inform your doctor about all medications, vitamins, and herbal supplements you are taking, as certain drugs may interact with iloprost.
• Monitoring: Regular monitoring of your response to iloprost therapy, as well as any side effects, is essential. Your doctor may perform tests to check your heart function and other parameters.
• Side Effects: Be aware of potential side effects such as headache, flushing, dizziness, nausea, vomiting, and jaw pain. Report any unusual symptoms to your doctor promptly.
• Administration: Follow the instructions provided by your healthcare provider for the correct administration of iloprost via inhalation. Use the nebulizer and inhalation technique as instructed.

Always follow your healthcare provider’s instructions closely when using iloprost or any medication to ensure safe and effective treatment.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Ciloprost. However, maintaining a healthy diet and lifestyle is generally recommended for managing pulmonary arterial hypertension and overall health. Your healthcare provider may advise you on dietary changes that can support your treatment plan, such as reducing salt intake if you have fluid retention.

What should I do if I forget a dose?

If you miss a dose of Ciloprost, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

What side effects can this medication cause?

Ciloprost (iloprost) can cause several side effects, which can vary in severity from mild to potentially serious. It’s important to be aware of these side effects and to promptly report any unusual symptoms to your healthcare provider. Here are some common side effects of Ciloprost:

• Headache: This is one of the most commonly reported side effects.
• Flushing (redness, warmth): This may occur due to dilation of blood vessels.
• Dizziness: Feeling lightheaded or dizzy can occur, especially when standing up quickly.
• Nausea and vomiting: Some people may experience gastrointestinal upset.
• Jaw pain: This can sometimes occur, especially if Ciloprost is administered via inhalation.
• Diarrhea: Gastrointestinal disturbances like diarrhea can occur in some individuals.
• Hypotension (low blood pressure): This can occur, leading to symptoms such as feeling faint or dizzy.
• Edema (swelling): Swelling, particularly in the legs or ankles, can occur due to fluid retention.
• Flu-like symptoms: These can include fever, chills, and body aches.
• Cough: Some people may experience coughing.
• Rash or itching: Skin reactions such as rash or itching may occur.
• Palpitations: Awareness of heartbeats or irregular heart rhythms may occur in some individuals.
• Injection site reactions: If administered intravenously, reactions at the injection site may occur, such as pain or redness.
• Muscle pain: Some individuals may experience muscle aches or discomfort.
• Rare but serious side effects: In rare cases, Ciloprost can cause serious side effects such as severe allergic reactions (anaphylaxis), serious bleeding, and worsening of underlying conditions like heart failure.

It’s important to note that not everyone experiences these side effects, and some people may have different reactions to the medication. If you experience any concerning or severe symptoms while taking Ciloprost, contact your healthcare provider immediately. They can provide guidance on managing side effects and may adjust your treatment regimen if necessary.

What should I know about storage and disposal of this medication?

Storage of Ciloprost:

• Temperature: Store Ciloprost ampules (containers with the medication) in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Do not freeze.
• Protection: Keep the ampules in their original packaging to protect from light.
• Stability: Once an ampule is opened and prepared for use in a nebulizer, it should be used immediately. Discard any unused portion.
• Handling: Follow any specific storage instructions provided by your healthcare provider or pharmacist.

Disposal of Ciloprost:

• Unused Medication: Unused Ciloprost ampules should be discarded properly. Do not keep outdated medicine or medicine no longer needed.
• Disposal Guidelines: Dispose of Ciloprost according to local regulations or guidelines. Your pharmacist can provide advice on safe disposal methods.

In case of emergency/overdose

• Symptoms: Symptoms of an overdose with Ciloprost may include severe headache, dizziness, nausea, vomiting, and low blood pressure.
• Seek Medical Help: If you suspect an overdose or experience severe side effects after using Ciloprost, seek emergency medical attention immediately.
• Poison Control: You can also contact your local poison control center (in the United States, call 1-800-222-1222) for guidance on what to do in case of overdose.

What other information should I know?

• Follow-Up Visits: Attend all scheduled appointments with your healthcare provider to monitor your response to Ciloprost and adjust your treatment plan as needed.
• Avoid Missing Doses: Try to take Ciloprost as prescribed. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Regular Monitoring: Your doctor may conduct tests to monitor your condition and check for any side effects of Ciloprost.
• Travel: If you need to travel, ensure you have an adequate supply of Ciloprost and any necessary equipment (such as a nebulizer). Plan for proper storage during travel, especially if refrigeration is required.
• Educational Resources: Understand how to use the nebulizer device properly for inhaling Ciloprost. Your healthcare provider or pharmacist can provide instructions and ensure you are comfortable with the technique.
• Lifestyle Considerations: Follow any lifestyle recommendations provided by your healthcare provider, such as dietary changes or activity restrictions.

By understanding these guidelines for storage, disposal, emergencies, and additional information, you can safely manage your treatment with Ciloprost under the supervision of your healthcare provider. Always consult your healthcare provider or pharmacist if you have any questions or concerns about your medication or treatment plan.