Why is this medication prescribed?

Zantac 75 is a brand name for ranitidine, which belongs to a class of medications known as H2 blockers. It is commonly prescribed to treat conditions related to excess stomach acid, such as:

• Gastroesophageal Reflux Disease (GERD): Zantac 75 can be used to manage symptoms of GERD, a condition where stomach acid flows back into the esophagus, causing heartburn and irritation.
• Peptic Ulcers: It is also prescribed to heal and prevent ulcers in the stomach and duodenum (the first part of the small intestine). Peptic ulcers can be caused by the erosion of the protective lining of these organs due to stomach acid.
• Zollinger-Ellison Syndrome: This is a rare condition where the stomach produces too much acid. Zantac 75 may be used in the management of this syndrome.

How should this medicine be used?

Here are some general guidelines:

• Dosage: The typical adult dose for Zantac 75 is 75 mg (milligrams) taken orally once or twice daily. The exact dosage and frequency may vary depending on the specific condition being treated.
• Administration: Zantac 75 is usually taken with or without food. The tablets should be swallowed whole with a glass of water. It’s essential to follow the prescribed dosage and administration instructions provided by the healthcare professional.
• Duration of Use: The duration of treatment can vary based on the condition being treated. It’s crucial to complete the prescribed course of medication even if symptoms improve before the completion of the treatment.
• Medical Supervision: Zantac 75 is typically available over-the-counter (OTC), but it’s important to consult with a healthcare professional before starting any new medication, especially for prolonged use. If symptoms persist or worsen, medical advice should be sought.
• Special Considerations: Individuals with certain medical conditions or those taking other medications should inform their healthcare provider before using Zantac 75, as there can be interactions or contraindications.

It’s important to note that as of last update, there have been recalls and regulatory actions related to ranitidine-containing products due to concerns about the presence of a potential carcinogen (NDMA). Therefore, it’s advisable to check for the latest information and consult a healthcare professional for the most current guidance on the use of ranitidine products.

Other uses for this medicine

Aside from the primary uses mentioned earlier, Zantac 75 (ranitidine) is sometimes prescribed or used off-label for certain conditions or situations. Some of these potential uses include:

• Erosive Esophagitis: Zantac 75 may be used in the treatment of erosive esophagitis, a condition where the esophagus becomes irritated and inflamed due to stomach acid.
• Stress Ulcer Prophylaxis: In certain medical situations, such as critical illness or after major surgery, Zantac 75 may be used to prevent stress ulcers.
• Aspiration Pneumonia: Zantac 75 might be considered in the prevention of acid aspiration pneumonia during anesthesia.

What special precautions should I follow?

Special precautions should be taken when using ranitidine, and it’s crucial to follow the healthcare provider’s recommendations. Here are some general precautions:

• Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should consult their healthcare provider before using Zantac 75 to assess potential risks and benefits.
• Kidney or Liver Impairment: Individuals with kidney or liver problems may require adjusted dosages of Zantac 75. It’s crucial to inform the healthcare provider about any pre-existing conditions.
• Allergies: Patients with known allergies to ranitidine or similar medications should avoid using Zantac 75.
• Interactions with Other Medications: Zantac 75 may interact with certain drugs, including antacids, sucralfate, ketoconazole, atazanavir, and certain antiretroviral drugs. Inform your healthcare provider about all medications you are taking.
• Long-Term Use: There have been concerns about the presence of NDMA (a potential carcinogen) in ranitidine products, leading to recalls and regulatory actions. Long-term use should be done under the guidance of a healthcare professional, and patients should stay informed about the latest updates regarding the safety of ranitidine-containing products.
• Symptom Monitoring: While taking Zantac 75, individuals should be attentive to any unusual symptoms and report them to their healthcare provider promptly.
• Regular Check-ups: For individuals on long-term treatment, regular check-ups with a healthcare provider are advisable to monitor the effectiveness of the medication and address any emerging concerns.

Always follow the specific guidance provided by your healthcare provider and the instructions on the medication label. If there are any doubts or concerns about the use of Zantac 75, it’s crucial to consult with a healthcare professional for personalized advice. Additionally, considering the recall of ranitidine products, it’s essential to stay informed about any updates or changes in recommendations regarding the use of ranitidine-containing medications.

What special dietary instructions should I follow?

Zantac 75 is typically taken with or without food. However, some foods and beverages may exacerbate acid reflux symptoms. It’s generally advisable to avoid:

• Spicy foods: These can irritate the stomach lining.
• Acidic foods: Citrus fruits, tomatoes, and juices can trigger acid reflux in some people.
• Fatty foods: High-fat meals can relax the lower esophageal sphincter, allowing stomach acid to flow back into the esophagus.

It’s important to note that individual responses to foods can vary, so it may be helpful to keep a food diary to identify any specific triggers.

What should I do if I forget a dose?

If you forget to take a dose of Zantac 75, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Zantac 75 (ranitidine) is generally well-tolerated, but like any medication, it can potentially cause side effects. Common side effects are usually mild and may include:

• Headache: Some individuals may experience headaches while taking Zantac 75.
• Dizziness: Feeling lightheaded or dizzy can occur in some cases.
• Constipation or Diarrhea: Changes in bowel habits may occur, but these are often temporary.
• Nausea or Vomiting: Some people may experience nausea or vomiting.
• Stomach Pain: Abdominal discomfort or pain can be a side effect.
• Muscle Pain: Some individuals may experience muscle pain or discomfort.

These side effects are typically transient and may resolve as your body adjusts to the medication. However, if any of these side effects persist or worsen, it’s important to notify your healthcare provider.

In rare cases, more serious side effects can occur. If you experience any of the following, seek medical attention immediately:

• Allergic Reactions: Symptoms may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.
• Irregular Heartbeat (Arrhythmias): Although uncommon, ranitidine has been associated with an increased risk of arrhythmias in some studies.
• Severe Stomach or Abdominal Pain: This could be a sign of a more serious condition and should be evaluated promptly.
• Yellowing of Eyes or Skin (Jaundice): This can be a sign of liver problems.
• Unexplained Weight Loss: This may be indicative of an underlying issue that needs attention.

It’s important to note that as of last update, there were concerns about the presence of NDMA (a potential carcinogen) in ranitidine products, leading to recalls and regulatory actions. It’s advisable to stay informed about any updates or changes in recommendations regarding the use of ranitidine-containing medications.

Always consult with your healthcare provider if you have questions or concerns about the side effects of Zantac 75. If you experience severe or persistent side effects, seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Zantac 75:

• Storage:
  • Store Zantac 75 at room temperature, away from excessive heat and moisture.
  • Keep the medication in its original packaging or container.
  • Avoid storing it in the bathroom, as moisture can degrade the medication.
• Disposal:
  • Follow any specific disposal instructions provided by your healthcare provider or pharmacist.
  • If no specific instructions are given, it is generally recommended to dispose of unused or expired medications through a drug take-back program.
  • If a take-back program is not available, follow the guidelines provided by your local waste disposal and recycling center. Many communities have specific guidelines for the disposal of medications to prevent environmental contamination.

In case of emergency/overdose

In the case of an emergency or suspected overdose, seek immediate medical attention or contact your local poison control center at 1-800-222-1222. Symptoms of overdose may include:

• Rapid heartbeat
• Fainting
• Confusion
• Unusual tiredness
• Loss of coordination

What other information should I know?

• Follow Instructions: Take Zantac 75 exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting your healthcare provider.
• Regular Monitoring: For individuals on long-term treatment, regular check-ups with a healthcare provider are advisable to monitor the effectiveness of the medication and address any emerging concerns.
• Inform Healthcare Providers: Make sure to inform all healthcare providers, including dentists and pharmacists, about your use of Zantac 75. This includes over-the-counter medications, herbal supplements, and vitamins.
• Potential Interactions: Zantac 75 may interact with certain medications. Inform your healthcare provider about all medications you are taking to avoid potential interactions.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Zantac 75 with your healthcare provider to assess potential risks and benefits.
• Stay Informed: Stay informed about any updates or recalls related to ranitidine-containing products, as regulatory actions have been taken due to concerns about the potential presence of NDMA.

Always consult with your healthcare provider or pharmacist for personalized advice and information based on your specific medical history and circumstances.