Why is this medication prescribed?

Zafirlukast is a medication primarily prescribed for the treatment of asthma. It belongs to a class of drugs known as leukotriene receptor antagonists. Leukotrienes are substances in the body that can cause inflammation, bronchoconstriction (narrowing of airways), and other symptoms of asthma. Zafirlukast works by blocking the action of leukotrienes, thereby helping to reduce the symptoms of asthma.

How should this medicine be used?

Here are some key points regarding the use of Zafirlukast:

Prescription for Asthma:

• Zafirlukast is typically prescribed for the chronic treatment of asthma in adults and children (over the age of 5) whose symptoms are not adequately controlled by other asthma medications such as inhaled corticosteroids.

Dosage and Administration:

• The dosage of Zafirlukast can vary based on factors such as age, weight, and the severity of asthma.
• It is usually taken orally, with or without food. However, it’s important to follow the specific instructions provided by the prescribing healthcare provider.
• Zafirlukast is often taken twice a day, and it’s crucial to take it consistently at the same times each day.
• The tablets should be swallowed whole and not crushed or chewed.

Monitoring and Adverse Effects:

• Patients taking Zafirlukast may need regular check-ups with their healthcare provider to monitor their asthma symptoms and adjust the medication if necessary.
• It’s important to report any side effects or changes in symptoms to the healthcare provider promptly.
• Common side effects may include headache and gastrointestinal issues, but serious side effects are rare.

Precautions and Contraindications:

• Zafirlukast should not be used for the treatment of acute asthma attacks. It is a long-term controller medication and not a rescue inhaler.
• Inform the healthcare provider about all other medications, including over-the-counter drugs and supplements, as interactions may occur.
• Zafirlukast may not be suitable for individuals with a history of liver problems.

Pregnancy and Breastfeeding:

• Pregnant or breastfeeding individuals should discuss the risks and benefits of Zafirlukast with their healthcare provider before using the medication.

It’s crucial to follow the specific guidance provided by the prescribing healthcare provider and to use Zafirlukast as part of an overall asthma management plan, which may include other medications and lifestyle measures. If you or someone you know has been prescribed Zafirlukast, it’s important to consult with a healthcare professional for personalized advice and guidance.

Other uses for this medicine

Zafirlukast is primarily indicated for the treatment of asthma, particularly as a long-term control medication. However, it’s important to note that medications may sometimes be used “off-label” for conditions other than those specifically approved by regulatory authorities. Zafirlukast has not been widely used for other purposes, and its primary application remains in asthma management.

What special precautions should I follow?

Special Precautions for Zafirlukast:

• Allergic Reactions: Inform your healthcare provider if you have a history of allergic reactions to Zafirlukast or any other medications.
• Liver Function: Zafirlukast is metabolized in the liver, so individuals with liver problems or a history of liver disease should use it with caution. Liver function may be monitored during treatment.
• Drug Interactions: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as herbal supplements. Zafirlukast may interact with other medications, and dose adjustments may be necessary.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Zafirlukast with your healthcare provider. The potential effects on the developing fetus or nursing infant should be carefully considered.
• Not for Acute Attacks: Zafirlukast is not intended for the treatment of acute asthma attacks. It is a preventive or maintenance medication and should not be used as a rescue medication.
• Monitoring: Regular monitoring of asthma symptoms and lung function may be necessary. Your healthcare provider may adjust the dosage based on your response to the medication.
• Pediatric Use: Zafirlukast is approved for use in children aged 5 and older for asthma. However, the dosage and safety in younger children should be discussed with a healthcare provider.
• Missed Doses: If a dose is missed, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses to make up for a missed one.

It’s crucial to follow your healthcare provider’s instructions and attend regular check-ups to monitor your response to Zafirlukast. If you experience any unusual or severe side effects, contact your healthcare provider promptly.

Since medication guidelines may evolve, it’s advisable to consult a healthcare professional or check more recent sources for the latest information on Zafirlukast.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with Zafirlukast. However, it’s advisable to take it with or without food as directed by your healthcare provider. If there have been any updates or changes in recommendations since then, your healthcare provider would provide the most current information.

What should I do if I forget a dose?

If you forget to take a dose of Zafirlukast:

• Take it as Soon as Possible: If you remember shortly after the missed dose, take it as soon as possible.
• Skip if Close to Next Dose: If it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule.
• Do Not Double Up: Do not double up on doses to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects.

What side effects can this medication cause?

Zafirlukast, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary. It’s important to note that the following list is not exhaustive, and individuals should consult their healthcare provider for personalized information. Common side effects of Zafirlukast may include:

• Headache: This is one of the more commonly reported side effects.
• Gastrointestinal Distress: Zafirlukast may cause stomach upset, nausea, diarrhea, or abdominal pain.
• Insomnia: Some individuals may experience difficulty sleeping.
• Liver Function Abnormalities: Zafirlukast can, in rare cases, affect liver function. Regular monitoring may be recommended, especially in individuals with pre-existing liver conditions.
• Allergic Reactions: While uncommon, allergic reactions to Zafirlukast may occur. Symptoms can include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience these symptoms.
• Neuropsychiatric Effects: Rarely, there have been reports of neuropsychiatric events such as aggression, agitation, hallucinations, depression, and suicidal thinking. If you or someone you know experiences such symptoms, contact a healthcare provider immediately.

It’s important to promptly report any unusual or severe symptoms to a healthcare provider. Additionally, some side effects may not be listed here, and individuals should refer to the medication’s official prescribing information or consult their healthcare provider for comprehensive details.

Always follow your healthcare provider’s guidance regarding the use of Zafirlukast. They can provide information about potential side effects based on your medical history and help manage any adverse reactions that may occur. If you are prescribed Zafirlukast and have concerns about side effects, discuss them with your healthcare provider for personalized advice.

What should I know about storage and disposal of this medication?

Storage and Disposal of Zafirlukast:

• Storage:
  • Store Zafirlukast at room temperature away from moisture and heat.
  • Keep it in its original container, and ensure that the container is tightly closed.
• Disposal:
  • Discard any expired or unused Zafirlukast according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

In the case of an overdose or emergency, contact your local poison control center at 1-800-222-1222 or seek emergency medical attention. Symptoms of overdose may include severe headache, hallucinations, or stomach pain.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Zafirlukast exactly as prescribed by your healthcare provider. Do not change the dose without consulting them.
• Regular Monitoring: Attend regular check-ups with your healthcare provider to monitor your response to the medication and discuss any concerns or side effects.
• Avoid Triggering Substances: Identify and try to avoid triggers that may worsen your asthma symptoms, in addition to taking Zafirlukast as prescribed.
• Inform Healthcare Provider: Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to check for potential interactions.
• Emergency Rescue Inhaler: Zafirlukast is not a rescue medication for acute asthma attacks. Always have a fast-acting inhaler on hand for sudden symptoms.
• Travel Considerations: If you are planning to travel, ensure you have an adequate supply of Zafirlukast, and be aware of any time zone changes that may affect your dosing schedule.
• Medical Alert Bracelet: If you have severe allergies or other medical conditions, consider wearing a medical alert bracelet in case of emergencies.
• Patient Education: Understand how to use Zafirlukast effectively and be aware of potential side effects. If you have any questions, consult your healthcare provider or pharmacist.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Zafirlukast with your healthcare provider.

Always consult your healthcare provider for personalized advice based on your health history and individual circumstances. If you have questions or concerns about Zafirlukast, do not hesitate to contact your healthcare provider for guidance.