WARNING

Xulane, like other hormonal contraceptives, comes with potential risks. It’s important to note that the risks vary from person to person, and not everyone will experience these issues. Here’s a brief overview of some potential risks associated with taking Xulane:

• Blood Clots: There is an increased risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (PE), particularly in women who smoke, are overweight, or have other risk factors.
• Cardiovascular Events: Hormonal contraceptives, including Xulane, may slightly increase the risk of heart attack and stroke, especially in women with pre-existing cardiovascular conditions.
• High Blood Pressure: Xulane may cause an increase in blood pressure, and regular monitoring is recommended, especially in women with hypertension.
• Liver Issues: Women with a history of liver disease or liver tumors should exercise caution, as hormonal contraceptives can affect liver function.
• Gallbladder Disease: Hormonal contraceptives may increase the risk of gallbladder disease, especially in older women.
• Migraines: Women who have migraines, especially those with aura, may have an increased risk of stroke while using hormonal contraceptives.
• Breast Cancer: Some studies suggest a slightly increased risk of breast cancer in women using hormonal contraceptives, but the overall risk is considered small.
• Changes in Mood: Hormonal contraceptives can impact mood in some individuals, potentially leading to mood swings or changes in libido.

It’s important for individuals considering or using Xulane to have an open and thorough discussion with their healthcare provider. Your healthcare provider will assess your individual health profile, taking into account factors such as age, smoking status, and medical history, to determine the most appropriate contraceptive method for you. Regular check-ups and monitoring can help manage and mitigate potential risks. If you experience severe or persistent side effects, consult your healthcare provider promptly.

Why is this medication prescribed?

Xulane is a brand name for a contraceptive patch that contains a combination of two hormones, ethinyl estradiol, and norelgestromin. It is prescribed as a hormonal contraceptive method to prevent pregnancy. The patch is applied to the skin and releases these hormones into the bloodstream, where they work to prevent ovulation (the release of an egg from the ovary) and thicken cervical mucus, making it more difficult for sperm to reach the egg.

How should this medicine be used?

Here are some key points on how Xulane is typically used:

• Application: The Xulane patch is applied to clean, dry skin. Common locations include the buttocks, abdomen, upper torso (excluding breasts), or the outer part of the upper arm. It should not be applied to irritated or damaged skin.
• Changing the Patch: A new patch is applied once a week for three weeks (21 days) in a row. After the third week, you have a patch-free week (week four) during which you will likely experience withdrawal bleeding, similar to a menstrual period.
• Start Date: The first patch is usually applied on the first day of your menstrual period. If you start using the patch on any other day, additional contraceptive methods may be needed for the first week.
• Consistency: It’s important to change the patch on the same day each week to maintain its effectiveness. Missing or changing the patch late may increase the risk of pregnancy.
• Skipping the Patch-Free Week: Some healthcare providers may recommend skipping the patch-free week and applying a new patch immediately to skip a period. This is safe and can be done continuously for several cycles if desired.
• Effectiveness: Xulane is most effective when used consistently and correctly. It does not protect against sexually transmitted infections (STIs), so additional precautions may be needed for STI prevention.

Always follow the specific instructions provided by your healthcare provider and read the patient information leaflet that comes with the medication. If you have any concerns or questions about the use of Xulane, it’s important to discuss them with your healthcare provider.

Other uses for this medicine

Xulane is primarily prescribed as a contraceptive method, but in some cases, healthcare providers may consider it for other uses. However, it’s essential to note that any off-label use should be discussed and approved by a healthcare professional. Off-label use refers to the use of a medication for a purpose other than what it was originally approved for by regulatory agencies.

What special dietary instructions should I follow?

Special precautions and considerations for using Xulane include:

• Medical History: Inform your healthcare provider about your complete medical history, especially if you have a history of blood clots, stroke, heart problems, liver disease, high blood pressure, diabetes, or if you smoke.
• Age and Smoking: Women who are over 35 years old and smoke are generally advised not to use hormonal contraceptives due to an increased risk of cardiovascular events.
• Pregnancy and Breastfeeding: Xulane is not intended for use during pregnancy. If you become pregnant or plan to become pregnant while using the patch, notify your healthcare provider. Additionally, it is generally not recommended for use while breastfeeding.
• Blood Clot Risk: The use of hormonal contraceptives, including Xulane, may increase the risk of blood clots. This risk is higher in women who smoke, are overweight, or have other risk factors for blood clots.
• Interaction with Other Medications: Inform your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, as well as herbal supplements. Some medications may interact with hormonal contraceptives, affecting their effectiveness.
• Side Effects and Warning Signs: Be aware of potential side effects and contact your healthcare provider if you experience severe abdominal pain, chest pain, shortness of breath, severe headaches, visual disturbances, or other symptoms that may indicate serious complications.

Always follow your healthcare provider’s recommendations and instructions for using Xulane or any other prescription medication. If you have specific concerns or questions about Xulane, discuss them with your healthcare provider for personalized advice based on your medical history and circumstances.

What special dietary instructions should I follow?

Generally, there are no specific dietary instructions for Xulane. However, it’s essential to maintain a healthy lifestyle, which includes a balanced diet and regular exercise. Some women may experience changes in appetite or weight while using hormonal contraceptives, and a healthy diet can contribute to overall well-being.

What should I do if I forget a dose?

If you forget to change your Xulane patch on the scheduled day, follow these general guidelines:

• Less than 48 Hours Late: If you realize you missed a patch change within 48 hours (two days) of the scheduled time, apply a new patch immediately. No additional contraceptive methods are needed.
• More than 48 Hours Late: If it’s been more than 48 hours since you were supposed to change the patch, apply a new patch as soon as you remember. Use an additional method of contraception, such as condoms, for the next seven days. If you had unprotected sex during this time, consider emergency contraception.

What side effects can this medication cause?

Xulane, like other hormonal contraceptives, may cause side effects. It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects that are not listed. If you are prescribed Xulane and have concerns about potential side effects, it’s crucial to discuss them with your healthcare provider. Here are some common side effects associated with Xulane:

• Local Skin Reactions: Redness, irritation, or itching at the site where the patch is applied.
• Breast Tenderness or Pain: Some women may experience breast tenderness or discomfort.
• Nausea and Vomiting: Nausea is a common side effect, especially when starting a new contraceptive method.
• Headache: Headaches, including migraines, may occur.
• Menstrual Changes: Irregular bleeding or spotting may occur, especially during the first few months of use.
• Mood Changes: Some individuals may experience mood swings, changes in libido, or mood-related symptoms.
• Weight Changes: Changes in weight, either an increase or decrease, are possible.
• Fluid Retention: Some women may experience bloating or fluid retention.
• Skin Changes: Changes in skin pigmentation or melasma (darkening of the skin) may occur, especially in individuals with a history of these conditions during pregnancy.
• Contact Lens Discomfort: Some women may experience discomfort with contact lenses.
• Serious Side Effects: Although rare, serious side effects may include blood clots, stroke, heart attack, and high blood pressure. The risk of these events may be higher in women who smoke, are overweight, or have other risk factors.

It’s important to seek medical attention if you experience severe or persistent side effects. Additionally, contact your healthcare provider if you have symptoms such as chest pain, severe abdominal pain, leg swelling, severe headaches, or vision changes, as these could be signs of serious complications.

Keep in mind that hormonal contraceptives, including Xulane, are prescription medications, and your healthcare provider will weigh the benefits against the potential risks based on your individual health profile. They can provide guidance on managing side effects and may adjust the treatment plan if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Xulane:

• Storage: Store Xulane patches at room temperature (around 68-77 degrees Fahrenheit or 20-25 degrees Celsius). Keep them in the original pouch until you are ready to use them. Avoid exposure to excessive heat or direct sunlight. Do not store in the bathroom.
• Disposal: Used patches still contain hormones, so it’s important to dispose of them properly. Fold each used patch in half with the sticky sides together and place it back into its protective pouch. Dispose of the used patches in the trash, out of the reach of children and pets. Do not flush them down the toilet.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention. Symptoms of an overdose may include nausea, vomiting, and withdrawal bleeding.

What other information should I know?

• Regular Check-ups: Regularly attend follow-up appointments with your healthcare provider to monitor your health and discuss any concerns or changes in your health.
• Medical and Laboratory Tests: Your healthcare provider may perform periodic blood pressure checks and other medical tests to monitor your response to Xulane and to check for any potential side effects or complications.
• Missed Menstrual Periods: It’s normal to experience withdrawal bleeding during the patch-free week. However, if you miss two consecutive menstrual periods, contact your healthcare provider to rule out pregnancy.
• Smoking: If you smoke, it’s important to discuss this with your healthcare provider. Smoking while using hormonal contraceptives increases the risk of cardiovascular side effects.
• Interaction with Other Medications: Inform your healthcare provider about all medications you are taking, including prescription and over-the-counter drugs, as well as herbal supplements. Some medications may interact with Xulane.
• Medical Conditions: Inform your healthcare provider about any medical conditions you have, including a history of blood clots, heart problems, or liver disease.
• Emergency Contraception: Xulane is not intended for use as emergency contraception. If you have unprotected sex and need emergency contraception, consult your healthcare provider.

Always follow the specific instructions provided by your healthcare provider and read the patient information leaflet that comes with the medication. If you have any questions or concerns, don’t hesitate to discuss them with your healthcare provider for personalized guidance.