WARNING

While Wellbutrin SR (sustained-release) can be an effective medication for treating certain conditions, it is essential to be aware of potential risks associated with its use. Here is a brief overview of some of the risks:

• Suicidal Thoughts: Antidepressants, including Wellbutrin SR, may increase the risk of suicidal thoughts, especially in the early stages of treatment. This risk is higher in individuals under the age of 25. Close monitoring and communication with healthcare providers are crucial.
• Seizures: Wellbutrin SR may lower the seizure threshold, and the risk of seizures is dose-related. Individuals with a history of seizures or conditions that may increase the risk of seizures should use Wellbutrin SR with caution.
• Allergic Reactions: Some individuals may experience allergic reactions to Wellbutrin SR, including rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical attention promptly if these symptoms occur.
• Interaction with Other Medications: Wellbutrin SR may interact with other medications. Inform your healthcare provider about all the medications, including over-the-counter drugs and herbal supplements, that you are taking.
• Mood Changes: Antidepressants, including Wellbutrin SR, may cause mood changes, including an increase in depressive symptoms or the emergence of manic episodes in individuals with bipolar disorder.
• Weight Loss: Weight loss is a common side effect of Wellbutrin SR, and in some cases, it may be unwanted. Monitoring weight changes and discussing concerns with a healthcare provider is important.
• Sexual Side Effects: Like many antidepressants, Wellbutrin SR may cause sexual side effects, such as changes in libido or difficulty achieving and maintaining an erection.
• Other Side Effects: Wellbutrin SR can cause other common side effects such as insomnia, dry mouth, headache, nausea, and dizziness.

It’s crucial for individuals considering or using Wellbutrin SR to have open and honest communication with their healthcare provider. The decision to use this medication should be based on a careful consideration of the potential risks and benefits, taking into account the individual’s medical history and current health status. Regular monitoring and follow-up appointments with healthcare providers are essential to manage and address any emerging issues. If you have concerns or experience side effects, consult with your healthcare provider promptly. Never adjust your dosage or discontinue the medication without professional guidance.

Why is this medication prescribed?

Wellbutrin XL (bupropion) is a prescription medication that is primarily prescribed to treat major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking by reducing withdrawal symptoms and the urge to smoke.

• Major Depressive Disorder (MDD): Wellbutrin XL is approved for the treatment of major depressive disorder, which is characterized by persistent feelings of sadness and a lack of interest or pleasure in daily activities.
• Seasonal Affective Disorder (SAD): SAD is a type of depression that occurs at a specific time of year, usually in the fall and winter when there is less sunlight. Wellbutrin XL may be prescribed to help alleviate symptoms associated with SAD.
• Smoking Cessation: Wellbutrin XL is also used as an aid in smoking cessation. It can help reduce cravings and withdrawal symptoms, making it easier for individuals to quit smoking.

How should this medicine be used?

It’s crucial to follow your healthcare provider’s instructions and the prescription label when using Wellbutrin XL. Here are some general guidelines:

• Dosage: The dosage will be determined by your healthcare provider based on your individual condition and response to treatment.
• Administration: Wellbutrin XL is usually taken orally, once daily in the morning. It’s important to take the medication at the same time each day.
• Swallow Whole: The tablets should be swallowed whole and not crushed, chewed, or broken, as this can affect the time-release mechanism.
• Food: Wellbutrin XL can be taken with or without food. However, it’s advisable to take it with food if you experience stomach upset.
• Consistency: It’s important to take Wellbutrin XL consistently to get the most benefit from the medication. If you miss a dose, do not double the next dose. Take the next scheduled dose as prescribed.
• Duration: Continue taking Wellbutrin XL for the full prescribed duration, even if symptoms improve. Suddenly stopping the medication may lead to withdrawal symptoms.
• Consultation: Always consult with your healthcare provider if you have any questions or concerns about the medication or its side effects.

It’s crucial to inform your healthcare provider about any other medications, supplements, or health conditions you have, as they can interact with Wellbutrin XL. Additionally, discuss any side effects or changes in your mood or behavior with your healthcare provider promptly. Do not stop taking Wellbutrin XL without consulting your healthcare provider.

Other uses for this medicine

In addition to its primary use for major depressive disorder (MDD), Wellbutrin XL is also used for:

• Seasonal Affective Disorder (SAD): It can be prescribed to treat symptoms of seasonal depression that occur in the fall and winter months.
• Smoking Cessation: Wellbutrin XL is used as an aid to help people quit smoking by reducing withdrawal symptoms and the urge to smoke.

What special precautions should I follow?

While Wellbutrin XL can be an effective medication, there are certain precautions and considerations to be aware of:

• Seizure Risk: Wellbutrin XL is associated with an increased risk of seizures, especially at higher doses. Individuals with a history of seizures, eating disorders, or conditions that lower the seizure threshold should use Wellbutrin XL with caution.
• Mental Health Monitoring: Wellbutrin XL can sometimes cause changes in mood or behavior, including suicidal thoughts. It’s important for individuals and their caregivers to be vigilant and report any unusual changes to a healthcare provider.
• Allergic Reactions: Allergic reactions to Wellbutrin XL are rare but can be serious. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Interactions: Wellbutrin XL can interact with other medications, including monoamine oxidase inhibitors (MAOIs), certain antipsychotics, and medications that lower the seizure threshold. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking.
• Pregnancy and Breastfeeding: The use of Wellbutrin XL during pregnancy and breastfeeding should be discussed with a healthcare provider. The potential benefits and risks must be carefully weighed.
• Alcohol Consumption: Limit alcohol consumption while taking Wellbutrin XL, as excessive alcohol use can increase the risk of seizures.

Always follow your healthcare provider’s instructions, attend regular follow-up appointments, and communicate any concerns or side effects promptly. This information is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with a healthcare provider for medical advice and guidance.

What special dietary instructions should I follow?

Wellbutrin XL generally does not require specific dietary restrictions. However, it’s advisable to take the medication with food if you experience stomach upset. Additionally, maintaining a healthy and balanced diet can contribute to overall well-being and may positively impact mood.

What should I do if I forget a dose?

If you forget to take a dose of Wellbutrin XL, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

If you have questions about missed doses or if you consistently have difficulty remembering to take your medication, consult your healthcare provider. They can provide guidance on how to manage missed doses and may adjust your treatment plan if necessary.

What side effects can this medication cause?

Wellbutrin XL (bupropion) may cause various side effects, and individuals may experience them to different extents. Common side effects are usually mild and may include:

• Insomnia or Sleep Disturbances: Some individuals may experience difficulty sleeping or changes in sleep patterns.
• Dry Mouth: Wellbutrin XL can lead to a reduction in saliva production, causing dry mouth.
• Nausea or Upset Stomach: Some people may experience mild gastrointestinal discomfort, including nausea or upset stomach.
• Headache: Headaches are a common side effect of Wellbutrin XL.
• Weight Loss: Wellbutrin XL is associated with a potential for weight loss, which can be a side effect for some individuals.
• Agitation or Restlessness: Some people may feel agitated, jittery, or restless while taking Wellbutrin XL.
• Dizziness: Dizziness or lightheadedness may occur, especially when standing up quickly.
• Increased Heart Rate: Wellbutrin XL can cause an increase in heart rate (tachycardia) for some individuals.
• Sweating: Excessive sweating or increased sweating may occur.
• Tremors: In some cases, individuals may experience mild tremors or shaky hands.
• Blurred Vision: Wellbutrin XL may cause temporary changes in vision, such as blurred vision.

It’s important to note that not everyone will experience these side effects, and some individuals may not experience any at all. Additionally, some side effects may diminish or go away over time as the body adjusts to the medication.

Serious side effects are rare but may include:

• Seizures: Wellbutrin XL is associated with an increased risk of seizures, especially at higher doses.
• Allergic Reactions: Serious allergic reactions are rare but can occur. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Mood Changes: Wellbutrin XL may cause changes in mood or behavior, including the emergence of suicidal thoughts. This is more common in the initial stages of treatment.
• Serotonin Syndrome: Although rare, Wellbutrin XL, like other antidepressants, can increase serotonin levels and, in rare cases, lead to serotonin syndrome, a potentially life-threatening condition.

It’s crucial to report any unusual or severe side effects to your healthcare provider promptly. Do not stop taking Wellbutrin XL without consulting your healthcare provider, as abruptly stopping the medication may lead to withdrawal symptoms or a return of depression symptoms. Your healthcare provider can adjust the dosage or recommend other appropriate measures if side effects are bothersome or severe.

What should I know about storage and disposal of this medication?

Storage and Disposal of Wellbutrin XL:

• Storage: Store Wellbutrin XL (bupropion) at room temperature, away from light and moisture. Keep the medication in its original packaging.
• Avoid High Temperatures: Do not expose Wellbutrin XL to high temperatures or store it in humid conditions, as this can affect the stability of the medication.
• Keep Out of Reach of Children: Store Wellbutrin XL in a location that is out of reach of children and pets.
• Do Not Share Medication: Wellbutrin XL is prescribed to you based on your specific medical condition. Do not share the medication with others, even if they have similar symptoms.
• Dispose Properly: When you no longer need the medication or it reaches its expiration date, dispose of it properly. Follow local guidelines for medication disposal, or ask your pharmacist for advice on how to safely dispose of unused or expired medications.

In case of emergency/overdose

In case of an emergency or overdose, seek medical attention immediately. The symptoms of a Wellbutrin XL overdose may include:

• Seizures
• Loss of consciousness
• Hallucinations
• Severe confusion
• Irregular heartbeat
• Severe dizziness or fainting

If someone is experiencing these symptoms, call emergency services (911 in the U.S.) or your local emergency number. It’s important to provide as much information as possible about the medication taken and the quantity.

What other information should I know?

• Regular Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to Wellbutrin XL and adjust the treatment plan as needed.
• Avoid Alcohol: Limit alcohol consumption while taking Wellbutrin XL, as excessive alcohol use can increase the risk of seizures.
• Inform Healthcare Providers: Inform all healthcare providers (including dentists and surgeons) about your use of Wellbutrin XL. This includes over-the-counter medications, herbal supplements, and other prescription drugs.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Wellbutrin XL with your healthcare provider. The decision to use the medication during pregnancy and breastfeeding should be made in consultation with your healthcare provider.
• Follow Instructions: Always follow your healthcare provider’s instructions regarding dosage, administration, and any specific recommendations or precautions.

As with any medication, it’s important to have open communication with your healthcare provider, ask questions, and promptly report any side effects or concerns. This information is not a substitute for professional medical advice. Always consult with a healthcare provider for medical advice and guidance tailored to your specific situation.