WARNING

Wegovy is a medication prescribed for weight management in adults with obesity or overweight and at least one weight-related comorbidity. While it can be effective for weight loss, like any medication, Wegovy comes with potential risks and side effects. It’s important to note that this information may not include the latest developments, and individuals should consult their healthcare provider for the most up-to-date information. Some potential risks associated with Wegovy include:

• Gastrointestinal Side Effects: Common side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain. These symptoms may be more pronounced when initiating the medication.
• Hypoglycemia: Semaglutide may lower blood sugar levels, leading to hypoglycemia, especially when used in conjunction with other antidiabetic medications.
• Injection Site Reactions: Redness, swelling, or itching at the injection site may occur.
• Pancreatitis: There have been reports of pancreatitis associated with the use of GLP-1 receptor agonists, including semaglutide.
• Thyroid Tumors: Animal studies have shown an increased risk of thyroid C-cell tumors with GLP-1 receptor agonists, but the relevance to humans is not fully established.
• Gallbladder Issues: Semaglutide may increase the risk of gallbladder-related events.
• Pregnancy Considerations: The safety of Wegovy during pregnancy and breastfeeding is not well-established, and individuals should consult with their healthcare provider if they are pregnant, planning to become pregnant, or breastfeeding.
• Digestive System Changes: GLP-1 receptor agonists, including semaglutide, can affect the normal movement of the digestive system, potentially leading to gastrointestinal issues.

It’s crucial for individuals considering Wegovy to have a thorough discussion with their healthcare provider. The decision to use this medication should be based on a careful assessment of the potential benefits and risks in the context of the individual’s health status and medical history. Always follow your healthcare provider’s instructions, attend regular follow-up appointments, and report any unusual or severe side effects promptly.

Why is this medication prescribed?

Wellbutrin XL (bupropion) is a prescription medication that is primarily prescribed to treat major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking by reducing withdrawal symptoms and the urge to smoke.

• Major Depressive Disorder (MDD): Wellbutrin XL is approved for the treatment of major depressive disorder, which is characterized by persistent feelings of sadness and a lack of interest or pleasure in daily activities.
• Seasonal Affective Disorder (SAD): SAD is a type of depression that occurs at a specific time of year, usually in the fall and winter when there is less sunlight. Wellbutrin XL may be prescribed to help alleviate symptoms associated with SAD.
• Smoking Cessation: Wellbutrin XL is also used as an aid in smoking cessation. It can help reduce cravings and withdrawal symptoms, making it easier for individuals to quit smoking.

How should this medicine be used?

As a general guideline, Wegovy is typically administered as a subcutaneous injection once a week. Here are some general steps for using Wegovy:

• Preparation: Before administering the injection, make sure to wash your hands thoroughly.
• Choose the Injection Site: The injection can be given in the abdomen, thigh, or upper arm. Rotate the injection site with each dose to reduce the risk of injection site reactions.
• Prepare the Injection: If you are using a pre-filled pen, follow the instructions provided with the pen to prepare the medication for injection. This may involve attaching a needle or dialing the correct dose.
• Clean the Injection Site: Use an alcohol swab to clean the injection site.
• Administer the Injection: Pinch the skin at the chosen injection site and insert the needle at a 90-degree angle. Administer the injection according to the instructions provided by your healthcare provider.
• Dispose of the Needle: Safely dispose of the needle and pen according to local regulations and guidelines.

Always follow the specific instructions provided by your healthcare provider and the medication’s packaging. If you have any questions or concerns about using Wegovy, it’s important to discuss them with your healthcare professional. They can provide guidance based on your individual health status and needs.

Remember, this information is based on my last update in September 2021, and there may have been changes or updates since then. Always refer to the most recent information and consult with your healthcare provider for personalized advice.

Other uses for this medicine

Wegovy (semaglutide 2.4 mg) is primarily prescribed for weight management in adults with obesity or overweight who have at least one weight-related comorbidity. However, it’s important to note that medication guidelines and approved uses may change over time, and new information might be available.

What special precautions should I follow?

Special precautions and considerations for Wegovy should be discussed with your healthcare provider, as individual health conditions and medical histories can vary. However, here are some general considerations and precautions that might apply to the use of Wegovy:

• Medical History: Inform your healthcare provider about your complete medical history, including any existing medical conditions, allergies, or medications you are currently taking.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, it’s crucial to discuss this with your healthcare provider. The safety of Wegovy during pregnancy and breastfeeding may not be well-established.
• Gastrointestinal Issues: GLP-1 receptor agonists, like semaglutide, may be associated with gastrointestinal side effects, such as nausea, vomiting, and diarrhea. If you have a history of gastrointestinal diseases or disorders, discuss this with your healthcare provider.
• Pancreatitis: There have been reports of pancreatitis with the use of GLP-1 receptor agonists. If you have a history of pancreatitis or other pancreatic conditions, inform your healthcare provider.
• Thyroid C-Cell Tumors: GLP-1 receptor agonists have been associated with an increased risk of thyroid C-cell tumors in rodents. It’s essential to discuss any family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) with your healthcare provider.
• Hypoglycemia: Semaglutide may lower blood sugar levels, so it’s important to be aware of the signs and symptoms of hypoglycemia (low blood sugar). This is particularly important if you are also taking medications for diabetes.

Always follow your healthcare provider’s instructions and discuss any concerns or questions you may have about Wegovy. Consult with your healthcare professional for the most current and personalized advice.

What special dietary instructions should I follow?

While on Wegovy, there may not be specific dietary instructions, but it’s essential to maintain a healthy lifestyle, including a balanced diet and regular physical activity. Your healthcare provider may provide personalized advice based on your health status and weight management goals.

What should I do if I forget a dose?

If you forget to take a dose of Wegovy, take it as soon as you remember, unless it is within 5 days of your next scheduled dose. In that case, skip the missed dose and take your next dose on the scheduled day. Do not take extra medicine to make up for a missed dose. Always follow the specific instructions provided by your healthcare provider and consult with them if you have any questions or concerns about your medication regimen.

What side effects can this medication cause?

Wegovy (semaglutide 2.4 mg) can have various side effects, and it’s important to be aware of them. However, the specific side effects can vary from person to person, and not everyone will experience the same reactions. Always consult with your healthcare provider for the most accurate and up-to-date information. Here are some potential side effects associated with Wegovy:

• Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, constipation, and abdominal pain. These symptoms are often more prominent when starting the medication and may improve over time.
• Hypoglycemia: Semaglutide may lower blood sugar levels, and hypoglycemia (low blood sugar) can occur, especially when used in combination with other antidiabetic medications. Symptoms of hypoglycemia may include sweating, shakiness, irritability, fast heartbeat, and dizziness.
• Injection Site Reactions: Redness, swelling, or itching at the injection site are possible side effects. Rotating injection sites can help minimize these reactions.
• Thyroid Tumors: In animal studies, semaglutide has been associated with an increased risk of thyroid C-cell tumors. However, the relevance of this finding to humans is not fully established.
• Pancreatitis: There have been reports of pancreatitis with the use of GLP-1 receptor agonists, including semaglutide. Symptoms of pancreatitis include persistent severe abdominal pain.
• Gallbladder Issues: Semaglutide may increase the risk of gallbladder-related events. Symptoms of gallbladder problems may include pain in the upper abdomen.

It’s important to report any unusual or severe side effects to your healthcare provider promptly. Additionally, individuals considering Wegovy should have a thorough discussion with their healthcare provider about the potential benefits and risks based on their individual health status and medical history.

Keep in mind that new information may have become available, and it’s essential to consult with a healthcare professional for the latest guidance and information.

What should I know about storage and disposal of this medication?

Storage:

• Temperature: Store Wegovy at the recommended temperature as specified in the medication’s instructions. Typically, this may involve refrigeration, but specific instructions may vary.
• Protection from Light: Some medications are sensitive to light, so be sure to follow any instructions regarding protection from light.
• Keep Out of Reach of Children: Store Wegovy in a safe place, out of reach of children and pets.

Disposal:

• Follow Local Regulations: Dispose of used needles and any remaining medication according to local regulations. Your healthcare provider or pharmacist can provide guidance on safe disposal methods.
• Do Not Flush: Do not flush medications down the toilet unless instructed to do so. This helps prevent environmental contamination.

In case of emergency/overdose

In case of an emergency or overdose, contact your local poison control center or emergency room immediately. If possible, have information about the medication, dosage, and the time it was taken available. Signs of an overdose or adverse reaction may include severe nausea, vomiting, and signs of hypoglycemia (low blood sugar).

What other information should I know?

• Follow Prescribed Dosage: Take Wegovy exactly as prescribed by your healthcare provider. Do not change the dosage or frequency without consulting your healthcare professional.
• Regular Monitoring: Your healthcare provider may monitor your response to Wegovy regularly. Attend follow-up appointments and laboratory tests as recommended.
• Inform Healthcare Providers: Inform all healthcare providers involved in your care that you are taking Wegovy, including dentists and emergency medical professionals.
• Interactions with Other Medications: Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, that you are taking to avoid potential interactions.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider, as the safety of Wegovy during pregnancy and breastfeeding may not be well-established.

Always keep the contact information for your healthcare provider readily available and seek medical attention if you experience severe or persistent side effects. So consult with your healthcare provider or pharmacist for the most current and personalized advice.