Why is this medication prescribed?

Vyleesi (bremelanotide) is a medication prescribed to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. HSDD is characterized by a persistent lack of sexual desire that causes distress or interpersonal difficulty. Vyleesi is specifically indicated for acquired, generalized HSDD, meaning it is not due to a co-existing medical or psychiatric condition, problems within the relationship, or the effects of a medication or substance.

How should this medicine be used?

Here are some key points about the use of Vyleesi:

• Administration: Vyleesi is administered as a subcutaneous injection, which means it is injected under the skin.
• Timing of Use: It is generally taken as needed, approximately 45 minutes before anticipated sexual activity.
• Dosage: The recommended dose is 1.75 mg, taken no more than once within a 24-hour period and no more than eight times per month.
• Response: The effectiveness of Vyleesi can vary from person to person. Some individuals may experience an increase in sexual desire, while others may not see a significant improvement.
• Side Effects: Common side effects may include nausea, flushing, and headache. It’s important to discuss any concerns or potential side effects with your healthcare provider.
• Precautions: Vyleesi is not recommended for use in men or for the treatment of sexual dysfunction in postmenopausal women. It should also be used with caution in individuals with cardiovascular disease or uncontrolled hypertension.

It’s crucial to consult with a healthcare professional before using Vyleesi to determine if it is an appropriate treatment for your specific situation. They can provide guidance on dosing, potential side effects, and address any concerns you may have. As with any prescription medication, it’s important to follow your healthcare provider’s instructions and report any unusual or severe side effects promptly.

Other uses for this medicine

Vyleesi (bremelanotide) is primarily indicated for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. It is not approved for other uses. However, it’s essential to note that new information or approvals may have emerged since then, so it’s recommended to consult the most recent medical resources or your healthcare provider for the latest information.

What special precautions should I follow?

Regarding special precautions for Vyleesi, here are some important considerations:

• Cardiovascular Health: Vyleesi can cause an increase in blood pressure and should be used with caution in individuals with cardiovascular disease or uncontrolled hypertension. Before starting Vyleesi, your healthcare provider should assess your cardiovascular health.
• Alcohol Consumption: The combination of Vyleesi with alcohol may increase the risk of side effects such as nausea and blood pressure changes. It’s advisable to limit alcohol intake while using Vyleesi.
• Interactions with Other Medications: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking. Certain medications may interact with Vyleesi, and adjustments to your treatment plan may be necessary.
• Pregnancy and Breastfeeding: The safety of Vyleesi during pregnancy and breastfeeding has not been established. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your healthcare provider.
• Side Effects: Be aware of the potential side effects of Vyleesi, which may include nausea, flushing, and headache. If you experience severe or persistent side effects, contact your healthcare provider.
• Frequency of Use: Follow your healthcare provider’s instructions regarding the frequency of Vyleesi use. Do not exceed the recommended dosage, and allow at least 24 hours between doses.
• Individual Response: Responses to Vyleesi can vary among individuals. Some may experience an increase in sexual desire, while others may not respond as significantly. It’s important to communicate openly with your healthcare provider about your experience.

Always consult with your healthcare provider before starting or discontinuing any medication, including Vyleesi. They can provide personalized advice based on your medical history and help determine if Vyleesi is an appropriate and safe option for you.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with the use of Vyleesi. However, it’s always a good practice to maintain a healthy and balanced diet, especially if you have any underlying health conditions. If you have specific concerns about diet and medication interactions, discuss them with your healthcare provider.

What should I do if I forget a dose?

Since Vyleesi is typically used as needed, forgetting a dose may not apply in the same way as with medications that are taken on a regular schedule. However, it’s crucial to adhere to the recommended dosing frequency provided by your healthcare provider. If you have any questions about the use of Vyleesi or if you miss a dose, contact your healthcare provider for guidance.

What side effects can this medication cause?

Vyleesi (bremelanotide) may cause side effects, and it’s important to be aware of them. Common side effects reported in clinical trials include:

• Nausea: Nausea is one of the most commonly reported side effects of Vyleesi. It may occur after administration and could be mild to moderate in intensity.
• Flushing (Hot Flashes): Flushing or hot flashes, characterized by a sudden feeling of warmth and redness in the face and upper body, can occur.
• Headache: Some individuals may experience headaches as a side effect of Vyleesi.

It’s important to note that not everyone will experience these side effects, and the intensity can vary from person to person. Additionally, side effects are generally temporary and tend to subside on their own. If you experience persistent or severe side effects, it’s important to contact your healthcare provider.

Less common, but more serious side effects can also occur. These can include an increase in blood pressure, so individuals with pre-existing cardiovascular conditions should use Vyleesi with caution and under the guidance of a healthcare professional.

As with any medication, it’s crucial to discuss your medical history and any concerns with your healthcare provider before starting Vyleesi. They can provide personalized advice based on your individual health profile and help you weigh the potential benefits against the risks. If you experience any unexpected or severe side effects while using Vyleesi, seek medical attention promptly.

Keep in mind that information is based on the status of knowledge, and there may have been updates or changes since then. Always consult with your healthcare provider or refer to the most recent prescribing information for the latest details on Vyleesi.

What should I know about storage and disposal of this medication?

Storage of Vyleesi:

• Temperature: Store Vyleesi at room temperature, typically between 68°F to 77°F (20°C to 25°C).
• Protect from Light: Keep the medication away from light, and store it in its original packaging.
• Do Not Freeze: Do not freeze Vyleesi.
• Keep Out of Reach of Children: Store Vyleesi in a location where it is inaccessible to children.

Always follow the specific storage instructions provided by the manufacturer or your healthcare provider.

Disposal of Vyleesi:

Follow any specific disposal instructions provided by your healthcare provider or the medication packaging. If you have questions about how to dispose of Vyleesi or any unused medication, consult your local waste disposal guidelines or your healthcare provider.

In case of emergency/overdose

In case of an emergency or overdose, seek immediate medical attention. The symptoms of an overdose with Vyleesi are not well-documented, and it’s essential to contact emergency services or a poison control center for guidance.

What other information should I know?

• Inform Healthcare Providers: Make sure to inform all healthcare providers involved in your care about your use of Vyleesi. This includes physicians, specialists, and emergency medical personnel.
• Regular Follow-ups: Attend scheduled follow-up appointments with your healthcare provider to monitor your response to Vyleesi and discuss any concerns or changes in your health.
• Patient Information: Familiarize yourself with the patient information leaflet that comes with the medication. It provides important details about the medication, its uses, potential side effects, and other relevant information.
• Communication with Healthcare Provider: If you experience any unusual or severe side effects, changes in your health, or if you have any questions or concerns, contact your healthcare provider promptly.

Always follow your healthcare provider’s instructions and guidelines for the use of Vyleesi, and do not hesitate to seek medical attention in case of emergencies or unexpected reactions. For the most up-to-date information, consult your healthcare provider or refer to the latest prescribing information for Vyleesi.