WARNING

Voltaren XR is a brand name for an extended-release form of diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID). It is commonly used to reduce inflammation and relieve pain in conditions such as osteoarthritis and rheumatoid arthritis. While Voltaren XR can be effective for managing pain, it is essential to be aware of potential risks and side effects associated with its use. It’s important to note that specific information about medications can change, and it’s always best to consult with a healthcare professional for the most up-to-date and personalized advice.

Some potential risks and side effects of Voltaren XR include:

• Gastrointestinal Issues: NSAIDs, including diclofenac, may increase the risk of gastrointestinal complications such as ulcers, bleeding, and perforation. These can be serious and potentially life-threatening.
• Cardiovascular Events: There may be an increased risk of cardiovascular events, including heart attack and stroke, particularly with long-term and high-dose use of NSAIDs.
• Renal (Kidney) Effects: NSAIDs can affect kidney function, leading to fluid retention, high blood pressure, and potential kidney problems, especially in individuals with pre-existing kidney conditions.
• Allergic Reactions: Some individuals may be allergic to diclofenac, experiencing symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing.
• Liver Problems: Rare cases of liver problems, including liver failure, have been reported with the use of diclofenac.
• Skin Reactions: Serious skin reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis, although rare, have been associated with diclofenac.
• Fluid Retention and Edema: NSAIDs can cause fluid retention, leading to edema (swelling), particularly in individuals with conditions such as heart failure or hypertension.
• Increased Blood Pressure: Diclofenac can lead to an increase in blood pressure, and regular monitoring is advisable, especially in individuals with hypertension.

It’s crucial to use Voltaren XR under the guidance of a healthcare professional, and they will consider your overall health, medical history, and potential interactions with other medications you may be taking. It’s important to promptly report any unusual or severe side effects to your healthcare provider. Additionally, NSAIDs like Voltaren XR should be used at the lowest effective dose for the shortest duration necessary to manage symptoms.

Why is this medication prescribed?

Voltaren XR, which contains diclofenac sodium, is a prescription medication commonly prescribed to manage pain and inflammation associated with certain conditions. Here are some of the common uses for which Voltaren XR may be prescribed:

• Osteoarthritis: Voltaren XR is often prescribed to relieve pain and reduce inflammation associated with osteoarthritis, a degenerative joint disease.
• Rheumatoid Arthritis: It may be used to manage pain and inflammation in individuals with rheumatoid arthritis, an autoimmune disorder affecting the joints.
• Ankylosing Spondylitis: This is a type of arthritis that primarily affects the spine. Voltaren XR may be used to alleviate symptoms such as pain and stiffness.
• Acute Gout: It can be prescribed for the management of acute gout attacks, which are caused by the deposition of uric acid crystals in the joints.
• Menstrual Pain: Voltaren XR may be used for the relief of pain associated with menstrual cramps.

How should this medicine be used?

Now, regarding how Voltaren XR should be used, it’s crucial to follow your healthcare provider’s instructions and the information provided on the prescription label. Here are general guidelines:

• Dosage: The dosage will be determined by your healthcare provider based on your specific condition, medical history, and other factors. It’s essential to take the prescribed dose and not exceed it.
• Administration: Voltaren XR is an extended-release tablet and is usually taken once daily with food to help reduce the risk of stomach upset. It’s important not to crush, chew, or break the tablet, as this can affect the extended-release properties.
• Duration of Use: Your healthcare provider will prescribe Voltaren XR for the shortest duration necessary to manage your symptoms effectively. Long-term use and high doses can increase the risk of side effects.
• Monitoring: Regular monitoring by your healthcare provider is important, especially if you are on long-term treatment. This includes checking for any signs of gastrointestinal issues, cardiovascular effects, or other potential side effects.
• Contraindications and Interactions: Inform your healthcare provider about any other medications, supplements, or medical conditions you have, as certain medications or conditions may interact with Voltaren XR or increase the risk of side effects.

Always consult with your healthcare provider if you have any questions or concerns about the use of Voltaren XR. It’s crucial to use this medication under professional guidance to ensure its effectiveness and minimize potential risks.

Other uses for this medicine

Some other conditions for which diclofenac, the active ingredient in Voltaren XR, might be used include:

• Pain Management: It can be prescribed for the relief of moderate to severe pain, such as pain following surgery or injury.
• Migraines: In some cases, diclofenac may be used to manage pain associated with migraines.
• Actinic Keratosis: Diclofenac, in the form of a topical gel, is used for the treatment of actinic keratosis, a skin condition caused by sun damage.
• Dysmenorrhea: It may be used to alleviate the pain associated with primary dysmenorrhea (menstrual cramps).

What special precautions should I follow?

As for special precautions, here are some important considerations:

• Gastrointestinal Risk: NSAIDs, including diclofenac, can increase the risk of serious gastrointestinal adverse events such as bleeding, ulceration, and perforation, which can be fatal. Individuals with a history of gastrointestinal issues should be closely monitored, and caution is advised.
• Cardiovascular Risk: There is a potential increased risk of cardiovascular events, including heart attack and stroke, associated with the use of NSAIDs. This risk may be higher in individuals with cardiovascular disease or risk factors.
• Renal Function: NSAIDs can affect renal function, and caution is needed in individuals with pre-existing kidney conditions or those at risk of renal impairment.
• Liver Function: Regular monitoring of liver function is advisable, as rare cases of liver problems, including liver failure, have been reported with diclofenac use.
• Fluid Retention and Hypertension: NSAIDs, including diclofenac, may cause fluid retention and increase blood pressure. This is particularly relevant for individuals with pre-existing conditions such as heart failure or hypertension.
• Allergic Reactions: Individuals who are allergic to diclofenac or other NSAIDs should not use Voltaren XR. Allergic reactions can be serious and may include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Use in Pregnancy and Lactation: The use of Voltaren XR should be avoided in late pregnancy, as it may harm the unborn baby. It may also pass into breast milk, so caution is advised during breastfeeding.

It’s crucial to inform your healthcare provider about all medications, supplements, and medical conditions you have before starting Voltaren XR. This information helps them make informed decisions about the appropriateness and safety of the medication for your specific situation. Regular check-ups and monitoring are essential during treatment with Voltaren XR. Always follow your healthcare provider’s instructions and report any unusual or severe side effects promptly.

What special dietary instructions should I follow?

• Take with Food: To reduce the risk of stomach upset, take Voltaren XR with food or milk.
• Avoid Alcohol: Alcohol can increase the risk of gastrointestinal bleeding, so it’s advisable to limit or avoid alcohol consumption while taking Voltaren XR.

What should I do if I forget a dose?

• Missed Dose: If you forget to take a dose of Voltaren XR, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Double Dosing: Do not double the dose to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects.
• Consult Your Healthcare Provider: If you are unsure about what to do or if you have missed multiple doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Voltaren XR (diclofenac sodium extended-release) can cause various side effects. It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects that are not listed here. Common side effects are usually mild, but if you experience severe or persistent symptoms, it’s crucial to contact your healthcare provider. Here are some potential side effects associated with Voltaren XR:

• Gastrointestinal Effects:
  • Stomach pain or upset
  • Nausea
  • Diarrhea
  • Indigestion
  • Constipation
• Cardiovascular Effects:
  • Increased blood pressure
  • Fluid retention
  • Swelling (edema)
• Hepatic Effects:
  • Mild liver enzyme elevations
  • Rare cases of severe liver problems (contact your healthcare provider if you experience symptoms like jaundice, dark urine, persistent nausea)
• Renal Effects:
  • Impaired kidney function
  • Fluid retention
• Central Nervous System Effects:
  • Headache
  • Dizziness
  • Nervousness
• Dermatological Effects:
  • Rash
  • Itching
  • Photosensitivity (increased sensitivity to sunlight)
  • Serious skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) – rare but serious
• Respiratory Effects:
  • Upper respiratory tract infections
  • Shortness of breath (contact your healthcare provider if you experience severe respiratory symptoms)
• Hematologic Effects:
  • Anemia
  • Increased bleeding time
• Allergic Reactions:
  • Allergic reactions, including anaphylaxis (a severe, potentially life-threatening reaction)

It’s important to seek medical attention if you experience signs of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or severe rash.

Additionally, Voltaren XR, like other nonsteroidal anti-inflammatory drugs (NSAIDs), is associated with an increased risk of serious cardiovascular events (heart attack, stroke) and gastrointestinal complications (bleeding, ulcers, perforation). The risk of these events may increase with the duration of use and with higher doses.

This list is not exhaustive, and individual responses to medications can vary. It’s crucial to report any unusual or severe side effects to your healthcare provider promptly. Your healthcare provider will weigh the benefits of the medication against the potential risks and will monitor you for any adverse effects during the course of treatment.

What should I know about storage and disposal of this medication?

Storage and Disposal of Voltaren XR:

• Storage:
  • Store Voltaren XR at room temperature, away from moisture and heat.
  • Keep it in its original packaging, and store it out of reach of children and pets.
  • Do not store in the bathroom, as moisture and humidity can affect the medication.
• Disposal:
  • Dispose of Voltaren XR according to local regulations and guidelines.
  • Do not flush medications down the toilet unless instructed to do so.
  • Check with your healthcare provider or local pharmacy for information on safe medication disposal.

In case of emergency/overdose

• Seek Immediate Medical Attention: If you suspect an overdose or experience symptoms such as severe stomach pain, vomiting, difficulty breathing, or unconsciousness, seek emergency medical attention immediately.
• Poison Control: In the United States, you can contact the Poison Control Center at 1-800-222-1222 for guidance on what to do in case of an overdose.

What other information should I know?

• Regular Monitoring: Your healthcare provider may conduct regular check-ups to monitor your response to Voltaren XR and assess for any potential side effects.
• Medical History: Inform your healthcare provider of your complete medical history, including any allergies, existing medical conditions, and a list of all medications you are taking, including prescription and over-the-counter drugs, as well as herbal supplements.
• Interactions: Discuss potential drug interactions with your healthcare provider. Certain medications may interact with Voltaren XR, affecting its effectiveness or increasing the risk of side effects.
• Avoid Alcohol: Limit or avoid alcohol while taking Voltaren XR, as it can increase the risk of gastrointestinal bleeding.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The use of Voltaren XR may need to be carefully considered in these situations.
• Sun Exposure: Use caution in exposure to sunlight and tanning beds, as Voltaren XR may increase sensitivity to sunlight. Use sunscreen and wear protective clothing.
• Follow Instructions: Take Voltaren XR exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking it without consulting your healthcare provider.
• Regular Blood Tests: Your healthcare provider may order periodic blood tests to monitor liver and kidney function, especially if you are on long-term treatment.

Always follow your healthcare provider’s advice and instructions regarding the use of Voltaren XR. If you have any concerns or questions, do not hesitate to contact your healthcare provider for clarification and guidance.