Why is this medication prescribed?

When treating some adults and adolescents 12 years of age or older who weigh at least 77 pounds (35 kg) for human immunodeficiency virus type 1 (HIV-1), cabotegravir and rilpivirine (Edurant) are administered in a short-term manner. When a person is 12 years of age or older and weighs at least 77 pounds (35 kg), cabotegravir is used to prevent HIV-1 infection in certain adults and adolescents for a brief period of time. Before getting the cabotegravir injection, it is used to test the body’s tolerance to the drug. It is also utilized in situations where a cabotegravir injection dose is missed.

Cabotegravir belongs to a group of drugs known as HIV integrase inhibitors. It functions by lowering blood levels of HIV. While cabotegravir does not treat HIV, it may lower your risk of contracting HIV-related diseases like cancer or serious infections as well as acquired immunodeficiency syndrome (AIDS). By taking these drugs, having safer sexual relations, and changing other aspects of your lifestyle, you may be able to reduce your risk of HIV transmission.

How should this medicine be used?

Here are general guidelines for how Cabotegravir is typically used:

• Dosage: The recommended oral dosage of cabotegravir can vary based on the specific treatment regimen and individual patient factors. Your healthcare provider will determine the appropriate dose for you.
• Administration: Take cabotegravir tablets as prescribed by your healthcare provider. It is typically taken once daily with or without food.
• Adherence: It is crucial to take the medication exactly as prescribed to ensure its effectiveness. Missing doses or not adhering to the prescribed regimen can reduce the drug’s ability to control HIV.
• Follow-Up: Regular follow-up appointments with your healthcare provider are important for monitoring your response to the medication and managing any potential side effects.

It’s crucial to communicate openly with your healthcare provider about your medical history, any other medications you are taking, and any concerns or questions you may have about cabotegravir. Always follow your healthcare provider’s instructions and attend all recommended appointments for optimal management of HIV and related conditions.

Other uses for this medicine

Cabotegravir is primarily used for the treatment of HIV-1 infection. However, research and clinical trials are ongoing to explore potential additional uses for this medication. It’s essential to consult with a healthcare professional or check more recent sources for any updates on approved uses.

What special precautions should I follow?

In terms of special precautions, individuals prescribed Cabotegravir should be aware of the following:

• HIV Testing Before Initiation: Before starting Cabotegravir, individuals should undergo testing to confirm that they are not already infected with HIV. This is important to ensure that the medication is used appropriately as part of a combination therapy for the treatment of HIV-1.
• Hypersensitivity Reactions: Patients should inform their healthcare provider of any known allergies or hypersensitivity reactions to Cabotegravir or any of its components. If signs of a hypersensitivity reaction (such as rash, fever, or other allergic symptoms) occur, medical attention should be sought.
• Pregnancy and Breastfeeding: The safety of Cabotegravir during pregnancy and breastfeeding is an important consideration. Pregnant individuals or those planning to become pregnant should discuss the risks and benefits of the medication with their healthcare provider. Additionally, breastfeeding individuals should consult their healthcare provider for guidance on the use of Cabotegravir.
• Interactions with Other Medications: Cabotegravir may interact with other medications, including over-the-counter drugs and herbal supplements. It’s crucial to inform the healthcare provider of all medications being taken to avoid potential interactions.
• Liver Function Monitoring: Cabotegravir may impact liver function, and therefore, regular monitoring of liver function through blood tests may be necessary during treatment.
• Adherence to Treatment: Adherence to the prescribed dosing schedule is critical for the effectiveness of Cabotegravir. Missing doses or deviating from the recommended schedule may lead to suboptimal control of HIV and may increase the risk of developing drug-resistant strains of the virus.

As with any medication, individuals should communicate openly with their healthcare provider, providing a comprehensive medical history and discussing any concerns or questions about Cabotegravir. The information provided here is general, and specific precautions may vary based on individual health circumstances. Always follow the guidance and recommendations of the healthcare professional managing your care.

What special dietary instructions should I follow?

As of last update, there were no specific dietary restrictions associated with Cabotegravir. However, it’s essential to maintain a healthy and balanced diet to support overall well-being. If there are updates or changes to dietary recommendations, your healthcare provider will inform you.

What should I do if I forget a dose?

If you forget to take an oral dose of Cabotegravir, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cabotegravir, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary. Additionally, some side effects may be temporary and improve over time. Common side effects of Cabotegravir include:

• Fever: Some individuals may experience fever as a side effect of Cabotegravir.
• Fatigue: Fatigue or feeling tired is another common side effect.
• Headache: Headaches are reported by some individuals taking Cabotegravir.
• Nausea: Nausea or an upset stomach can occur in some cases.
• Dizziness: Some individuals may experience dizziness.
• Abnormal Liver Function Tests: Cabotegravir may affect liver function, and as a result, periodic monitoring of liver function through blood tests is typically recommended.

It’s important to promptly report any unusual or severe side effects to your healthcare provider. Additionally, if you experience signs of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or severe rash, seek emergency medical attention.

It’s worth noting that the information provided here is based on last update, and there may have been updates or changes since then. Always consult with your healthcare provider or refer to the most recent medical information for the latest details on medication side effects.

What should I know about storage and disposal of this medication?

Storage and Disposal of Cabotegravir:

• Storage: Follow the storage instructions provided by your healthcare provider or pharmacist. In general, Cabotegravir oral tablets should be stored at room temperature away from moisture and heat.
• Disposal: Dispose of unused or expired Cabotegravir according to local regulations and guidelines. Do not flush medications down the toilet unless specifically instructed to do so. If you have any questions about how to dispose of medications, consult your healthcare provider or pharmacist.

In case of emergency/overdose

In case of emergency or a suspected overdose, seek medical attention immediately. The signs of an overdose or adverse reaction may include severe allergic reactions, difficulty breathing, or other serious symptoms. Contact your local poison control center or emergency room for guidance. Provide them with as much information as possible, including the name of the medication (Cabotegravir) and the amount ingested.

What other information should I know?

• Regular Follow-up: Attend all scheduled appointments with your healthcare provider for regular check-ups and monitoring. This is important to assess your response to Cabotegravir and to detect any potential side effects or complications.
• Adherence to Treatment: Adherence to the prescribed dosing schedule is crucial for the effectiveness of Cabotegravir. If you have any difficulty adhering to the schedule or have concerns about the medication, discuss them with your healthcare provider.
• Communication with Healthcare Provider: Inform your healthcare provider of any changes in your health status, including the development of new symptoms or the occurrence of side effects.
• Other Medications and Supplements: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as any herbal supplements you are taking. Some medications or supplements may interact with Cabotegravir.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. The risks and benefits of Cabotegravir in these situations should be carefully evaluated.
• Routine Laboratory Tests: Your healthcare provider may perform routine laboratory tests, including liver function tests, to monitor your overall health and response to Cabotegravir.

Always follow the specific instructions provided by your healthcare provider and the medication’s packaging. The information provided here is general, and individual circumstances may warrant additional considerations. If you have specific questions or concerns about Cabotegravir, consult with your healthcare provider for personalized guidance.