WARNING

Vivitrol is a brand name for the extended-release injectable form of naltrexone, a medication used to treat alcohol and opioid dependence. While Vivitrol can be effective in supporting recovery, it does come with certain risks and potential side effects. It’s important to note that individual responses to medications can vary, and you should consult with a healthcare professional for personalized advice. Some potential risks and side effects of Vivitrol include:

• Injection Site Reactions: Pain, swelling, or redness at the injection site is common.
• Digestive Issues: Nausea, vomiting, and stomach cramps are reported side effects.
• Liver Damage: In rare cases, naltrexone, the active ingredient in Vivitrol, may cause liver damage. Regular monitoring of liver function is typically recommended.
• Allergic Reactions: Some individuals may experience allergic reactions, such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Opioid Withdrawal: Vivitrol blocks the effects of opioids, and if someone has opioids in their system when they receive the injection, it can precipitate withdrawal symptoms.
• Depression and Suicidal Thoughts: There have been reports of mood-related side effects, including depression and suicidal thoughts, though the causal relationship is not fully understood.
• Interaction with Opioid Analgesics: Vivitrol may reduce the effectiveness of opioid pain medications, and individuals on Vivitrol may be more sensitive to the effects of opioids.

It’s crucial to discuss your medical history, current medications, and any concerns with your healthcare provider before starting Vivitrol or any other medication. They can provide more detailed information about potential risks and help you make an informed decision based on your individual health needs.

Why is this medication prescribed?

Vivitrol is prescribed to individuals who are undergoing treatment for alcohol dependence or opioid dependence. The active ingredient in Vivitrol is naltrexone, which is an opioid receptor antagonist. It works by blocking the effects of opioids and reducing the cravings for alcohol. The extended-release formulation of Vivitrol, administered by injection, provides a sustained release of naltrexone over a one-month period.

How should this medicine be used?

Here’s a general overview of how Vivitrol is typically used:

• Initiation of Treatment: Before starting Vivitrol, individuals must be opioid-free for a minimum of 7-10 days to avoid precipitating withdrawal symptoms. This period may be longer for certain opioids.
• Medical Assessment: Prior to prescribing Vivitrol, healthcare providers conduct a thorough medical assessment to ensure the individual is an appropriate candidate for the medication. This includes assessing liver function and considering potential interactions with other medications.
• Injection Administration: Vivitrol is administered by a healthcare professional as a deep intramuscular gluteal injection. The injection is typically given once a month.
• Monitoring and Follow-up: Regular monitoring of liver function may be recommended during Vivitrol treatment. Healthcare providers will also monitor for any side effects or changes in the individual’s condition.
• Psychosocial Support: Vivitrol is most effective when used as part of a comprehensive treatment program that includes psychosocial support, counseling, and other therapeutic interventions.

It’s essential for individuals considering Vivitrol to discuss their medical history, including any history of liver disease or opioid use, with their healthcare provider. Vivitrol is not a standalone solution but is intended to be used in conjunction with counseling and other support measures as part of a comprehensive approach to addiction treatment. Always follow your healthcare provider’s instructions and attend scheduled appointments for proper monitoring and support.

Other uses for this medicine

Vivitrol is primarily used for the treatment of alcohol dependence and opioid dependence. However, it’s important to note that medications, including Vivitrol, are prescribed at the discretion of healthcare professionals based on individual patient needs and circumstances. Off-label use of medications (use for conditions other than those officially approved by regulatory authorities) may occur, but it should only be done under the guidance and supervision of a qualified healthcare provider.

What special precautions should I follow?

Vivitrol is primarily indicated for the prevention of relapse to opioid dependence, following opioid detoxification, and for the treatment of alcohol dependence in conjunction with psychosocial support. Any new indications or off-label uses that may have been approved after this date would need to be verified with more recent sources.

Regarding special precautions for Vivitrol, it’s important to consider the following:

• Allergies: Inform your healthcare provider about any allergies you may have, especially to naltrexone or any other ingredients in Vivitrol.
• Opioid Dependence: Before starting Vivitrol, individuals must be opioid-free for at least 7-10 days to prevent precipitating withdrawal symptoms.
• Liver Function: Regular monitoring of liver function may be necessary during Vivitrol treatment, as naltrexone can affect liver enzymes.
• Pregnancy and Breastfeeding: The safety of Vivitrol during pregnancy and breastfeeding is not well-established. Discuss potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant.
• Interaction with Opioid Analgesics: Vivitrol may reduce the effectiveness of opioid pain medications. Inform all healthcare providers about Vivitrol treatment before receiving any opioid-containing medications.
• Psychiatric Symptoms: Vivitrol has been associated with psychiatric side effects, including depression and suicidal thoughts. If you experience changes in mood or behavior, notify your healthcare provider.

Always follow your healthcare provider’s instructions and attend scheduled appointments for proper monitoring and support. It’s crucial to have open communication with your healthcare team about your medical history, any medications you are taking, and any concerns you may have while using Vivitrol. This information is not exhaustive, and individual circumstances may vary, so consult with your healthcare provider for personalized advice.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with Vivitrol. However, maintaining a healthy and balanced diet is generally advisable for overall well-being, especially during addiction treatment.

What should I do if I forget a dose?

If you forget a dose of Vivitrol, contact your healthcare provider as soon as possible to discuss the situation. It’s crucial to maintain the recommended dosing schedule for Vivitrol to ensure its effectiveness. Missing a dose may increase the risk of relapse, particularly in the case of opioid dependence. Do not attempt to administer a double dose to make up for a missed one without consulting your healthcare provider.

What side effects can this medication cause?

Vivitrol, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and the severity can vary from person to person. Common side effects of Vivitrol may include:

• Injection Site Reactions: Pain, swelling, or redness at the injection site is a common side effect.
• Digestive Issues: Nausea, vomiting, and stomach cramps may occur.
• Headache: Some individuals may experience headaches.
• Insomnia: Difficulty sleeping can be a side effect for some people.
• Joint and Muscle Pain: Pain in the joints and muscles may occur.
• Decreased Appetite: Some individuals may experience a decrease in appetite.
• Fatigue: Feeling tired or lethargic is a reported side effect.
• Liver Enzyme Changes: Vivitrol may lead to changes in liver enzymes. Regular monitoring of liver function may be necessary.
• Depression and Suicidal Thoughts: There have been reports of mood-related side effects, including depression and suicidal thoughts, though the causal relationship is not fully understood.
• Allergic Reactions: Allergic reactions to Vivitrol are rare but can include rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s important to seek medical attention if you experience severe or persistent side effects. Additionally, Vivitrol has specific considerations for individuals with liver problems or those taking opioid pain medications, so it’s crucial to inform your healthcare provider about your medical history and any medications you are currently taking.

This is not an exhaustive list of side effects, and individual responses may vary. Always consult with your healthcare provider for personalized advice and guidance on potential side effects associated with Vivitrol.

What should I know about storage and disposal of this medication?

Here are some important considerations regarding the storage and disposal information related to Vivitrol:

• Storage:
  • Store Vivitrol at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep it in the original carton to protect it from light.
  • Do not freeze Vivitrol.
• Disposal:
  • Dispose of used syringes and needles in a puncture-resistant container.
  • Follow local regulations for the proper disposal of medication. Your healthcare provider or pharmacist can provide guidance on how to dispose of Vivitrol safely.

In case of emergency/overdose

• In case of an emergency or overdose, seek immediate medical attention or contact your local poison control center at 1-800-222-1222.
• Symptoms of overdose may include difficulty breathing, severe dizziness, or unconsciousness.

What other information should I know?

• Inform all healthcare providers about Vivitrol treatment before receiving any opioid-containing medications, as Vivitrol may reduce the effectiveness of such medications.
• Attend regular appointments with your healthcare provider for monitoring and support during Vivitrol treatment.
• Report any new or worsening symptoms, especially changes in mood or behavior, to your healthcare provider promptly.

It’s essential to follow your healthcare provider’s instructions carefully and communicate openly about your medical history, any medications you are taking, and any concerns you may have. If you have questions about Vivitrol or its administration, consult with your healthcare team for personalized guidance.

As a reminder, information provided here is based on knowledge, and it’s advisable to consult more recent sources or your healthcare provider for any updates or changes in guidelines.