Why is this medication prescribed?

Viberzi (eluxadoline) is a medication prescribed for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. IBS-D is a functional gastrointestinal disorder characterized by abdominal pain or discomfort, and altered bowel habits, primarily diarrhea.

Viberzi is a prescription medication that works by activating specific receptors in the digestive system, which helps to reduce bowel contractions and alleviate symptoms associated with IBS-D.

How should this medicine be used?

Here are general guidelines on how Viberzi should be used:

• Dosage: The usual recommended dose is 100 mg taken orally twice daily with food.
• Administration: Take Viberzi with food to reduce the risk of experiencing abdominal pain. Swallow the tablets whole with water; do not crush or chew them.
• Adherence to Prescription: Follow your healthcare provider’s prescription instructions carefully. Do not take more or less of the medication than prescribed, and do not stop taking it without consulting your healthcare provider.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
• Overdose: If you suspect an overdose or experience severe side effects, seek medical attention immediately.
• Special Considerations: Inform your healthcare provider about any other medications, supplements, or medical conditions you have, as they may affect the use of Viberzi.

It’s important to note that Viberzi is not recommended for use in individuals without a gallbladder, as it may increase the risk of pancreatitis. Additionally, some people may experience constipation as a side effect of Viberzi.

Always consult with your healthcare provider before starting or stopping any medication, and make sure to discuss any concerns or questions you may have about your treatment plan.

Other uses for this medicine

Viberzi (eluxadoline) was primarily indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. Its use for other conditions or purposes would depend on subsequent developments and approvals by regulatory authorities.

What special precautions should I follow?

Special precautions should be taken when using Viberzi, and it’s crucial to follow your healthcare provider’s advice. Here are some general precautions and considerations:

• Gallbladder Issues: Viberzi is not recommended for individuals without a gallbladder, as it may increase the risk of pancreatitis.
• Pancreatic Conditions: Inform your healthcare provider if you have a history of pancreatitis or other pancreatic disorders.
• Constipation Risk: Some individuals may experience constipation as a side effect of Viberzi. If you have a history of constipation or other gastrointestinal disorders, discuss this with your healthcare provider.
• Alcohol Consumption: Avoid excessive alcohol consumption while taking Viberzi, as it may increase the risk of pancreatitis.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Viberzi with your healthcare provider. The safety of Viberzi during pregnancy and breastfeeding is not well established.
• Liver Impairment: Viberzi may be associated with an increased risk of liver enzyme elevations. Inform your healthcare provider about any pre-existing liver conditions.
• Other Medications: Provide a complete list of all medications, including prescription and over-the-counter drugs, as well as supplements, to your healthcare provider to avoid potential interactions.
• Allergies: Inform your healthcare provider about any known allergies to medications or other substances.
• Side Effects: Be aware of potential side effects, including constipation, abdominal pain, nausea, and vomiting. If you experience severe or persistent side effects, contact your healthcare provider.

Always take Viberzi exactly as prescribed by your healthcare provider, and do not adjust the dosage without consulting them first. If you have any concerns or questions about the medication, discuss them with your healthcare provider for personalized advice based on your medical history and current health status. Additionally, since medical information can change, it’s essential to consult with a healthcare professional or check updated sources for the latest information on Viberzi.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with Viberzi. However, taking Viberzi with food is recommended to reduce the risk of abdominal pain. Follow your healthcare provider’s advice regarding your diet, especially if you have specific dietary restrictions or concerns.

What should I do if I forget a dose?

If you forget to take a dose of Viberzi, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Viberzi (eluxadoline) may cause various side effects, and it’s important to be aware of them. Common side effects may include:

• Constipation: This is one of the more common side effects of Viberzi.
• Nausea: Some individuals may experience nausea after taking Viberzi.
• Abdominal Pain: Abdominal pain or discomfort can occur, and it is recommended to take Viberzi with food to reduce the risk of abdominal pain.
• Gas: Increased gas may be a side effect.
• Vomiting: Some people may experience vomiting as a side effect.
• Upper Respiratory Tract Infection: This may include symptoms like a cough or a sore throat.
• Flatulence: Increased production of gas in the digestive system.
• Elevated Liver Enzymes: In some cases, Viberzi may be associated with increased levels of liver enzymes.

In rare cases, more serious side effects can occur. These may include:

• Pancreatitis: Inflammation of the pancreas, which can cause abdominal pain.
• Sphincter of Oddi Spasm: This is a rare but potentially serious side effect that can cause abdominal pain.

If you experience severe or persistent side effects, it’s important to contact your healthcare provider promptly. Additionally, if you have a history of pancreatitis, problems with your gallbladder, or other gastrointestinal issues, it’s crucial to inform your healthcare provider before starting Viberzi.

This is not an exhaustive list of side effects, and individual reactions may vary. Always consult with your healthcare provider for personalized advice and to discuss any concerns you may have regarding the use of Viberzi. If you experience a medical emergency or severe side effects, seek immediate medical attention.

What should I know about storage and disposal of this medication?

Storage and Disposal of Viberzi:

• Storage:
  • Store Viberzi at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep the medication in its original container, tightly closed, and away from light and moisture.
  • Do not store it in the bathroom.
• Disposal:
  • Dispose of Viberzi in accordance with local regulations and guidelines.
  • Do not flush medications down the toilet unless specifically instructed to do so.
  • Consult with your pharmacist or local waste disposal company for proper disposal methods.

In case of emergency/overdose

In case of an emergency or overdose, seek immediate medical attention or contact a poison control center. Symptoms of overdose may include severe constipation, severe abdominal pain, and other adverse reactions. Be sure to inform healthcare providers of the medication taken and the amount ingested.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Viberzi exactly as prescribed by your healthcare provider. Do not alter the dosage without consulting them.
• Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor your response to the medication and discuss any concerns or side effects.
• Inform Healthcare Providers: Inform all healthcare providers involved in your care about your use of Viberzi, including dentists and emergency medical personnel.
• Avoid Alcohol: Limit or avoid alcohol consumption while taking Viberzi, as it may increase the risk of pancreatitis.
• Interactions with Other Medications: Inform your healthcare provider about all medications, supplements, and over-the-counter drugs you are taking, as Viberzi may interact with certain substances.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Viberzi with your healthcare provider.
• Symptoms of Pancreatitis: Be aware of symptoms of pancreatitis, such as severe abdominal pain that may radiate to the back, and seek medical attention if you experience such symptoms.
• Allergic Reactions: Seek immediate medical attention if you experience signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Always consult with your healthcare provider for personalized advice and to address any specific concerns or questions you may have about the use of Viberzi. Additionally, keep in mind that information may have been updated since last update, so it’s advisable to consult with your healthcare provider or check more recent sources for any updates.